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Streptococcus pneumoniae G54 (spne4)
Gene : uvrA
DDBJ      :uvrA         excinuclease ABC, A subunit
Swiss-Prot:UVRA_STRR6   RecName: Full=UvrABC system protein A;         Short=UvrA protein;AltName: Full=Excinuclease ABC subunit A;

Homologs  Archaea  29/68 : Bacteria  892/915 : Eukaryota  6/199 : Viruses  0/175   --->[See Alignment]
c.37.1e.11.1
:943 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->943 2r6fB PDBj 0.0 67.5 %
:RPS:PDB   2->364 1bjtA PDBj 7e-75 11.8 %
:RPS:PDB   481->895 3dt2A PDBj 1e-28 9.9 %
:RPS:SCOP  1->383 1bgwA  e.11.1.1 * 6e-71 13.6 %
:RPS:SCOP  482->585,624->652 1l7vC  c.37.1.12 * 1e-14 35.1 %
:RPS:SCOP  594->652 1q3hA  c.37.1.12 * 9e-06 23.4 %
:RPS:SCOP  638->904 1f2t.1  c.37.1.12 * 3e-22 21.5 %
:HMM:SCOP  5->571 1ii8.1 c.37.1.12 * 5.6e-53 23.1 %
:HMM:SCOP  497->661 1t9hA2 c.37.1.8 * 2.5e-06 28.6 %
:HMM:SCOP  612->915 1f2t.1 c.37.1.12 * 7.5e-54 24.7 %
:HMM:PFM   446->517 PF00005 * ABC_tran 8.4e-09 38.7 62/118  
:HMM:PFM   648->861 PF00005 * ABC_tran 2.2e-15 28.7 115/118  
:HMM:PFM   620->669 PF03193 * DUF258 7.7e-06 31.2 48/161  
:HMM:PFM   915->929 PF12399 * BCA_ABC_TP_C 0.00095 46.7 15/23  
:BLT:SWISS 1->943 UVRA_STRR6 0.0 99.8 %
:PROS 489->503|PS00211|ABC_TRANSPORTER_1
:PROS 830->844|PS00211|ABC_TRANSPORTER_1
:REPEAT 2|403->597|761->939
:REPEAT 2|5->115|614->717
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56502.1 GT:GENE uvrA GT:PRODUCT excinuclease ABC, A subunit GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 176262..179093 GB:FROM 176262 GB:TO 179093 GB:DIRECTION + GB:GENE uvrA GB:PRODUCT excinuclease ABC, A subunit GB:NOTE identified by match to protein family HMM PF00005; match to protein family HMM TIGR00630 GB:PROTEIN_ID ACF56502.1 GB:DB_XREF GI:194358054 GB:GENE:GENE uvrA LENGTH 943 SQ:AASEQ MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKKGQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNLQNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE GT:EXON 1|1-943:0| SW:ID UVRA_STRR6 SW:DE RecName: Full=UvrABC system protein A; Short=UvrA protein;AltName: Full=Excinuclease ABC subunit A; SW:GN Name=uvrA; OrderedLocusNames=spr0171; SW:KW ATP-binding; Complete proteome; Cytoplasm; DNA damage; DNA excision;DNA repair; DNA-binding; Excision nuclease; Metal-binding;Nucleotide-binding; Repeat; SOS response; Zinc; Zinc-finger. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->943|UVRA_STRR6|0.0|99.8|943/943| GO:SWS:NREP 10 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA excision| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0004518|"GO:nuclease activity"|Excision nuclease| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0009432|"GO:SOS response"|SOS response| PROS 489->503|PS00211|ABC_TRANSPORTER_1|PDOC00185| PROS 830->844|PS00211|ABC_TRANSPORTER_1|PDOC00185| NREPEAT 2 REPEAT 2|403->597|761->939| REPEAT 2|5->115|614->717| SEG 905->923|gpeggvgggtiivtgtpee| BL:PDB:NREP 1 BL:PDB:REP 3->943|2r6fB|0.0|67.5|855/864| RP:PDB:NREP 2 RP:PDB:REP 2->364|1bjtA|7e-75|11.8|355/679| RP:PDB:REP 481->895|3dt2A|1e-28|9.9|406/621| HM:PFM:NREP 4 HM:PFM:REP 446->517|PF00005|8.4e-09|38.7|62/118|ABC_tran| HM:PFM:REP 648->861|PF00005|2.2e-15|28.7|115/118|ABC_tran| HM:PFM:REP 620->669|PF03193|7.7e-06|31.2|48/161|DUF258| HM:PFM:REP 915->929|PF12399|0.00095|46.7|15/23|BCA_ABC_TP_C| RP:SCP:NREP 4 RP:SCP:REP 1->383|1bgwA|6e-71|13.6|361/679|e.11.1.1| RP:SCP:REP 482->585,624->652|1l7vC|1e-14|35.1|126/231|c.37.1.12| RP:SCP:REP 594->652|1q3hA|9e-06|23.4|57/265|c.37.1.12| RP:SCP:REP 638->904|1f2t.1|3e-22|21.5|242/288|c.37.1.12| HM:SCP:REP 5->571|1ii8.1|5.6e-53|23.1|338/370|c.37.1.12|1/2|P-loop containing nucleoside triphosphate hydrolases| HM:SCP:REP 497->661|1t9hA2|2.5e-06|28.6|91/0|c.37.1.8|2/2|P-loop containing nucleoside triphosphate hydrolases| HM:SCP:REP 612->915|1f2t.1|7.5e-54|24.7|287/0|c.37.1.12|2/2|P-loop containing nucleoside triphosphate hydrolases| OP:NHOMO 1316 OP:NHOMOORG 927 OP:PATTERN ----------------1---1---11111111111---1111121112-2111-------------11 2341433222222211111-12111311111124443233122232132222333213112232322244422224221122111111222223222--2222324242311111111111111222222222322222221113111111111111111111111111111111111111112121111111122222221121122122111112211122113222222231111111111111133224223133112223322332112221111111211111222222222221111111111111111111111113221333234212135111111311111111133311111111111111423111111111113121111111111111111111-222221121111111112112211111112211111111212222221112111111111111--11111111111111111111211112222222222322222324322221222323221122222322232222211111111111111111122121211111111111111112211111114412111111111111111-11111111111111211112121111111111111111112--12222------11121111111111111-11-1111111111111111111111111111111111111111111111111-111111111111--1112222111111112111211111-111111112211121111111222212222111111111111111111111111111132222221111111111111111111111111211111-1-11111111111111111111211111111223 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1--------1----------1--1-----1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 943 STR:RPRED 100.0 SQ:SECSTR cHHHHcccTTTcccHHHHHHHHHHHHHTccccEEHHHHHHHHHHHTcccccccHHHHHHHHHcccTTccccccEEEEccccccTTTTcTEEEETcccGGGcEEEEcTTHHHHccGGGGGGccTcEEEEccccHHHHHHHHHHHHTTccccccccccTTcccEEEEHEETTEEEEEcEEEEEETTEEEEEEccTTccHHHHHHHHHHHHcccTTccccccEEEEcccccccEEEEccHHHHHHHHHHcHHHHTTcEEEEEcTTEEEEcTTccEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTccccTTccHHHHHHHHHHTTccEEcTTccEEcccccTTcccTTTcccHHHHTccGGGHHHcccEEEETTTEEEEEcHHHHHHHHHHccTTGGGcccccccGGEEGGGccccTTcHHHHHHHHHHHccHHHHHHHHHHHHHHHHcccEEEEEEcHHHHHHHHTccccccEEEccGGGHHHHHHHcccGGGcTTccHHHHHHHHHTTccccHHHHHHccHHHHHHHHcHHHHHHHHHHHTccTcccccccccccccEEHHHEEEEccccccccccTTHHHHHHHTcHHHHHHHHHHcccEEEEEEEEcccccHccccccEEEEEEccHHHcHHHHHHHHHHcTTccccGGGcEEEEEGGTEEEEEccccHHHHcTTTHHHHTHHHHHHHHHHTcEEEccEEEEccEEEcTTccEEEEEEEccTTccHHHHHTcccccTTcEEEEEEcccEEEEEccccEEEEEcTTccTTTcHHHHHHTTcccEEEccEETTccccccTTccEEcTTccEEcTTcccccccTTcTTcEEEEEGGGcTTccTTTTcTTcEEEEEEEccccccEEEcccHHHHHHHHHHHHcccccGGGcccEEEcccHHHHHTcTTcHHHHHHHHHHHHH DISOP:02AL 1-2,92-95,389-390,941-944| PSIPRED cccEEEEEccccccccccEEEEccccEEEEEcccccccHHHHHHHHHHHHHHHHHHHccHHHHHHccccccccccEEcccccEEEEEEcccccccccccccHHHHHHHHHHHHHHHccccccccccccccccHHHHHHHHHccccccEEEEEEEEEccccccHHHHHHHHHHcccEEEEEccEEEEccccccccccccccEEEEEEEEEEccccHHHHHHHHHHHHHHcccEEEEEEccccEEEEEEccccccccEEccccccccccccccccccccccccEEEEEccHHHccccccccHHHcccccccccccHHHHHHHHHHHHHccccccccHHHccHHHHHHHHccccccEEEEEEEcccccEEEEEEEEccHHHHHHHHHHccccHHHHHHHHHHHccccccccccccccHHHcEEEEccEEcHHHHHHHcccHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHHHHHccccEEEEEccccccccHHHHHHHHHHHHHHHHcccEEEEEEccHHHHHHccEEEEEcccccccccEEEEcccHHHHHHcccHHHHHHHccccccccccccccccccEEEEccccccccccEEEEEccccEEEEEEEccccHHHHHHHHHHHHHHHHHcccccccccccccccccccccEEEEccccccccccccccHHHcccHHHHHHHcccHHHHHcccccHHEEccccccccccccccEEEEEcccccccEEEEccccccccccccEEEEEEEEccHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHcccccccccccHHHccHHHHHHHHHHHHHHHccccccEEEEEcccccccHHHHHHHHHHHHHHHHcccEEEEEEEcHHHHHHccEEEEccccccccccEEEEEccHHHHHHcccHHHHHHHHHHHccc //