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Streptococcus pneumoniae G54 (spne4)
Gene : uvrC
DDBJ      :uvrC         excinuclease ABC, C subunit
Swiss-Prot:UVRC_STRP4   RecName: Full=UvrABC system protein C;         Short=Protein uvrC;AltName: Full=Excinuclease ABC subunit C;

Homologs  Archaea  27/68 : Bacteria  884/915 : Eukaryota  6/199 : Viruses  0/175   --->[See Alignment]
a.2.9a.60.2d.15.2d.198.1d.226.1
:615 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->97 1yd6D PDBj 3e-28 57.3 %
:BLT:PDB   192->225 2nmvA PDBj 3e-04 41.2 %
:BLT:PDB   280->380 2eenA PDBj 6e-04 38.6 %
:BLT:PDB   368->523 3c65A PDBj 3e-44 59.2 %
:BLT:PDB   536->584 1kftA PDBj 2e-06 40.8 %
:RPS:PDB   12->64 3egaA PDBj 8e-09 11.3 %
:RPS:PDB   101->189 3brgC PDBj 5e-07 17.0 %
:RPS:PDB   186->231 1e52A PDBj 1e-06 34.8 %
:RPS:PDB   230->384 1ds0A PDBj 4e-18 16.8 %
:RPS:PDB   368->523 3c65A PDBj 9e-52 61.9 %
:RPS:PDB   536->596 2a1jA PDBj 8e-10 21.3 %
:RPS:SCOP  16->96 1ln0A  d.226.1.1 * 3e-14 14.8 %
:RPS:SCOP  197->291 1oeyJ  d.15.2.2 * 7e-20 13.2 %
:RPS:SCOP  406->518 1xkpB1  d.198.1.1 * 6e-28 14.2 %
:RPS:SCOP  522->603 1z00B1  a.60.2.5 * 2e-15 17.1 %
:HMM:SCOP  14->97 1mk0A_ d.226.1.1 * 2.4e-23 50.0 %
:HMM:SCOP  181->236 1e52A_ a.2.9.1 * 2e-12 41.1 %
:HMM:SCOP  503->609 1dgsA1 a.60.2.2 * 5.1e-20 34.6 %
:RPS:PFM   16->69 PF01541 * GIY-YIG 4e-09 40.7 %
:RPS:PFM   369->523 PF08459 * UvrC_HhH_N 5e-40 51.9 %
:HMM:PFM   371->523 PF08459 * UvrC_HhH_N 1.1e-59 53.9 152/155  
:HMM:PFM   16->90 PF01541 * GIY-YIG 1.5e-13 34.7 75/80  
:HMM:PFM   197->228 PF02151 * UVR 2.1e-10 43.8 32/36  
:HMM:PFM   538->578 PF01367 * 5_3_exonuc 6.4e-05 25.0 40/101  
:BLT:SWISS 1->615 UVRC_STRP4 0.0 100.0 %
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56685.1 GT:GENE uvrC GT:PRODUCT excinuclease ABC, C subunit GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 547324..549171 GB:FROM 547324 GB:TO 549171 GB:DIRECTION + GB:GENE uvrC GB:PRODUCT excinuclease ABC, C subunit GB:NOTE identified by match to protein family HMM PF01541; match to protein family HMM PF02151; match to protein family HMM PF08459; match to protein family HMM TIGR00194 GB:PROTEIN_ID ACF56685.1 GB:DB_XREF GI:194358237 GB:GENE:GENE uvrC LENGTH 615 SQ:AASEQ MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCFYYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEASVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP GT:EXON 1|1-615:0| SW:ID UVRC_STRP4 SW:DE RecName: Full=UvrABC system protein C; Short=Protein uvrC;AltName: Full=Excinuclease ABC subunit C; SW:GN Name=uvrC; OrderedLocusNames=SPG_0561; SW:KW Complete proteome; Cytoplasm; DNA damage; DNA excision; DNA repair;Excision nuclease; SOS response. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->615|UVRC_STRP4|0.0|100.0|615/615| GO:SWS:NREP 6 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA excision| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0004518|"GO:nuclease activity"|Excision nuclease| GO:SWS GO:0009432|"GO:SOS response"|SOS response| COIL:NAA 26 COIL:NSEG 1 COIL:REGION 346->371| SEG 71->86|nieallleinlikenk| BL:PDB:NREP 5 BL:PDB:REP 2->97|1yd6D|3e-28|57.3|96/96| BL:PDB:REP 192->225|2nmvA|3e-04|41.2|34/620| BL:PDB:REP 280->380|2eenA|6e-04|38.6|83/177| BL:PDB:REP 368->523|3c65A|3e-44|59.2|147/149| BL:PDB:REP 536->584|1kftA|2e-06|40.8|49/56| RP:PDB:NREP 6 RP:PDB:REP 12->64|3egaA|8e-09|11.3|53/214| RP:PDB:REP 101->189|3brgC|5e-07|17.0|88/414| RP:PDB:REP 186->231|1e52A|1e-06|34.8|46/56| RP:PDB:REP 230->384|1ds0A|4e-18|16.8|149/323| RP:PDB:REP 368->523|3c65A|9e-52|61.9|147/149| RP:PDB:REP 536->596|2a1jA|8e-10|21.3|61/62| RP:PFM:NREP 2 RP:PFM:REP 16->69|PF01541|4e-09|40.7|54/80|GIY-YIG| RP:PFM:REP 369->523|PF08459|5e-40|51.9|154/156|UvrC_HhH_N| HM:PFM:NREP 4 HM:PFM:REP 371->523|PF08459|1.1e-59|53.9|152/155|UvrC_HhH_N| HM:PFM:REP 16->90|PF01541|1.5e-13|34.7|75/80|GIY-YIG| HM:PFM:REP 197->228|PF02151|2.1e-10|43.8|32/36|UVR| HM:PFM:REP 538->578|PF01367|6.4e-05|25.0|40/101|5_3_exonuc| GO:PFM:NREP 6 GO:PFM GO:0004518|"GO:nuclease activity"|PF01541|IPR000305| GO:PFM GO:0005622|"GO:intracellular"|PF01541|IPR000305| GO:PFM GO:0006281|"GO:DNA repair"|PF01541|IPR000305| GO:PFM GO:0003677|"GO:DNA binding"|PF08459|IPR001162| GO:PFM GO:0004518|"GO:nuclease activity"|PF08459|IPR001162| GO:PFM GO:0006289|"GO:nucleotide-excision repair"|PF08459|IPR001162| RP:SCP:NREP 4 RP:SCP:REP 16->96|1ln0A|3e-14|14.8|81/92|d.226.1.1| RP:SCP:REP 197->291|1oeyJ|7e-20|13.2|91/105|d.15.2.2| RP:SCP:REP 406->518|1xkpB1|6e-28|14.2|106/121|d.198.1.1| RP:SCP:REP 522->603|1z00B1|2e-15|17.1|82/83|a.60.2.5| HM:SCP:REP 14->97|1mk0A_|2.4e-23|50.0|84/97|d.226.1.1|1/1|GIY-YIG endonuclease| HM:SCP:REP 181->236|1e52A_|2e-12|41.1|56/56|a.2.9.1|1/1|C-terminal UvrC-binding domain of UvrB| HM:SCP:REP 503->609|1dgsA1|5.1e-20|34.6|107/181|a.60.2.2|1/1|RuvA domain 2-like| OP:NHOMO 970 OP:NHOMOORG 917 OP:PATTERN ------------------------11111111111---1111111111-1111-------------11 1111111111111121211-12112111111111112222211222121111111111111221112111211111111111211111111111112--1111111112111111111111111111111111121111111111211111111111111111111211111111111111111111111111111111111111111111111111111111112222221111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111222222222212111221111211111111122111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111-111111111111111111111---------1122111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--11111111111111111111111111-111111111111111111111111111111111111111111111111111111211111111111111111-1111111111111111111111-1-11111111111111111111111111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3--1-1---------1--1-----1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 603 STR:RPRED 98.0 SQ:SECSTR ccHHHccEEEEcccccccEEEEcTTccEEcccccTTcccccccTTccccTTcEEEccccEEEEEcEEEEccccccccEEEcccTTTTccccccccccEE#HHHHcccEEEEEEEEcEEEcccTTccccccEEEEEcTHHHHHHHHHHHTTccHHHHcEEEEEEcccc#ccccEEEcEEEcTTccccTTccccccHHHHHHHHHHHHHHHHHTEcGGGcEEEcccHHHHHHHHHHcccccccccccEEEEEEccTTcHHHHHHHHHTTccTTcEEEEEEcccccHHHHHHHHHHHHHHcccEEHHEEEEccccHHHHHHHHHHTTcEEGGGccTTTHHHHHHHHHHHHHHHTTcccHHHHHHTTccccEEcccTTcccccEEEEEEEEEccccEEEEEEEEEcTTccEEEEEEcccEEGGGHHHHHHHHHHHHHHHHHHTcTTTccccccEEEEEEEccccccHHHHHHHHHHHHHHHHHTTcccTTcEEEEEEEEcccEEEccccEEEccccEEEEEEEccccEEEEEEEEEEEEEcccTTTHHHHHHHHHHHHHHHTTccTTccccccccHHHHHHHHHHHHHHHHHHTTcccccccccccHHH########## DISOP:02AL 1-2,327-327,329-330,353-363,529-542,604-616| PSIPRED ccHHHHHHHHHccccccEEEEEcccccEEEEEEcHHHHHHHHHHHcccccHHHHHHHHHcccEEEEEEccHHHHHHHHHHHHHHHcccccEEccccccccEEEEccccccEEEEEEcccccccEEEcccccHHHHHHHHHHHHHHHccccccccccccccHHHcccccccccccccHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccEEccccccEEEEEEEEEccEEEEEEEEEEccEEccccccEEcccccHHHHHHHHHHHHHHccccccccEEEccccccHHHHHHHHccEEEEcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccEEEEEEEccccccccEEEEEEEEcccccHHHccEEEEcccccccHHHHHHHHHHHHHHHHHHcccccccEEEEEccHHHHHHHHHHHHHHccccccEEEEEccccccccEEEEcccccEEEcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHcccHHHHHHccHHHHHHccccHHHHHHHHHHHcccccHHHHHHHHcccccccccccccc //