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Thermobifida fusca YX (tfus0)
Gene : AAZ54649.1
DDBJ      :             acetolactate synthase, large subunit
Swiss-Prot:             

Homologs  Archaea  56/68 : Bacteria  764/915 : Eukaryota  178/199 : Viruses  0/175   --->[See Alignment]
c.31.1c.36.1c.92.2
:589 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->574 3ea4A PDBj e-129 45.8 %
:RPS:PDB   6->555 1bfdA PDBj e-117 22.4 %
:RPS:SCOP  2->534 1fp4B  c.92.2.3 * 3e-75 9.1 %
:HMM:SCOP  1->186 1ybhA2 c.36.1.5 * 2.7e-61 47.5 %
:HMM:SCOP  186->362 1jscA1 c.31.1.3 * 4.5e-67 59.6 %
:HMM:SCOP  370->589 2djiA3 c.36.1.9 * 5.4e-66 41.3 %
:RPS:PFM   5->165 PF02776 * TPP_enzyme_N 3e-34 45.3 %
:RPS:PFM   197->327 PF00205 * TPP_enzyme_M 3e-37 61.8 %
:RPS:PFM   407->552 PF02775 * TPP_enzyme_C 5e-24 45.9 %
:HMM:PFM   5->171 PF02776 * TPP_enzyme_N 1.2e-58 46.1 167/172  
:HMM:PFM   394->552 PF02775 * TPP_enzyme_C 2.5e-50 42.3 149/150  
:HMM:PFM   195->330 PF00205 * TPP_enzyme_M 4.2e-49 55.1 136/137  
:BLT:SWISS 3->589 ILVB_MYCTU 0.0 68.6 %
:PROS 431->450|PS00187|TPP_ENZYMES
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ54649.1 GT:GENE AAZ54649.1 GT:PRODUCT acetolactate synthase, large subunit GT:DATABASE GIB00263CH01 GT:ORG tfus0 GB:ACCESSION GIB00263CH01 GB:LOCATION 707643..709412 GB:FROM 707643 GB:TO 709412 GB:DIRECTION + GB:PRODUCT acetolactate synthase, large subunit GB:PROTEIN_ID AAZ54649.1 GB:DB_XREF GI:71914747 InterPro:IPR000399 InterPro:IPR004407 LENGTH 589 SQ:AASEQ MTEQMTGAQSLIRALEHVGVDVVFGIPGGAILPAYDPLYDSTKVRHILMRHEQGAGHAAEGYAYATGRPGVCIATSGPGATNLVTPLADAYMDSVPVVAITGQVASPAIGTDAFQEADICGITMPITKHNFLVRDPSKIASTIAEAFHIASTGRPGPVLVDIAKDALQAQTRFEWPQRPELPGYRPVTKPHGKQVREAARLIAEAKRPVLYVGGGVFKSGASKELRVLAELTGIPVVTTLMALGTFPSSHPQNLGMPGMHGTVAAVGALQRADLIVALGARFDDRVTGKLSSFAPHATIVHADIDPAEISKNRYADVPIVGDCREVIADLIVAVRADQAAGRQGDYTAWWEQLNRMRETYPLGYTEPEDGSLAPQYVIKRIGQIVGPDATYVAGVGQHQMWAAQFIDHQRPGSFVNSGGAGTMGFAIPAALGAKVGDPDRVIWAIDGDGCFQMTNQELATCAIEGIPIKVAVINNGNLGMVRQWQTLFYDGRYSNTNLHTAPTPEDGKVRIPDFVRLAEAYGCVGLRCDRAEDVDATIEKAMAINDVPVVIDFTVHHDAMVWPMVPAGVSNDDIQYARDMAPEWDDEEE GT:EXON 1|1-589:0| BL:SWS:NREP 1 BL:SWS:REP 3->589|ILVB_MYCTU|0.0|68.6|580/618| PROS 431->450|PS00187|TPP_ENZYMES|PDOC00166| SEG 51->65|heqgaghaaegyaya| BL:PDB:NREP 1 BL:PDB:REP 7->574|3ea4A|e-129|45.8|559/581| RP:PDB:NREP 1 RP:PDB:REP 6->555|1bfdA|e-117|22.4|518/523| RP:PFM:NREP 3 RP:PFM:REP 5->165|PF02776|3e-34|45.3|161/170|TPP_enzyme_N| RP:PFM:REP 197->327|PF00205|3e-37|61.8|131/138|TPP_enzyme_M| RP:PFM:REP 407->552|PF02775|5e-24|45.9|135/139|TPP_enzyme_C| HM:PFM:NREP 3 HM:PFM:REP 5->171|PF02776|1.2e-58|46.1|167/172|TPP_enzyme_N| HM:PFM:REP 394->552|PF02775|2.5e-50|42.3|149/150|TPP_enzyme_C| HM:PFM:REP 195->330|PF00205|4.2e-49|55.1|136/137|TPP_enzyme_M| GO:PFM:NREP 5 GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF02776|IPR012001| GO:PFM GO:0000287|"GO:magnesium ion binding"|PF00205|IPR012000| GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF00205|IPR012000| GO:PFM GO:0003824|"GO:catalytic activity"|PF02775|IPR011766| GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF02775|IPR011766| RP:SCP:NREP 1 RP:SCP:REP 2->534|1fp4B|3e-75|9.1|496/522|c.92.2.3| HM:SCP:REP 1->186|1ybhA2|2.7e-61|47.5|183/0|c.36.1.5|1/2|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 186->362|1jscA1|4.5e-67|59.6|171/0|c.31.1.3|1/1|DHS-like NAD/FAD-binding domain| HM:SCP:REP 370->589|2djiA3|5.4e-66|41.3|208/0|c.36.1.9|2/2|Thiamin diphosphate-binding fold (THDP-binding)| OP:NHOMO 3168 OP:NHOMOORG 998 OP:PATTERN 11-1--4554455554-31221143--21121243222222221312213343211-----2321-11 3361932233323254644-44336C444445354554EE2224323-232196754311535355A98621222111-211711111223112--111-1111142211---------------21111111111222331111734524432211113221222333721111111211111211111-134555553471455435334434545235242-4444432524434344444444424434122145112-27622553331343231111---22222222222222-------------211222111122135-------5-42133111-112--2122165222121221112--1-112222-11-123CB92148357633333332316-66755939672-544346A775896413168942356675555555543322332-----------------------------3334226D98899AAA985555AADE888847A7H789723654333227255B73333111311111111112422-922212222233512213112442222352621111111111-1-------1111211322231312222332422322222322233-1-311111111155554555666576766-6646767656666665664767753347466556667658564965666651-75555554655511---1---222232762222222-22213222222221312342988849454588633332----1---313253333322222332222222211111111331132------------------------111----------11--1-111222 ----22--1-----153313333765722222222224142442332223234811321322211313-1333312222321112123-11132111111111222-16-42322221-1112-11-516G2-22311111-13212112111321113364162111122234121118111235125123223111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 588 STR:RPRED 99.8 SQ:SECSTR #TccEcHHHHHHHHHHHTTccEEEEcccGGGHHHHTTccTTcTcEEEEcccHHHHHHHHHHHHHHHTccEEEEEEHHHHHHHTHHHHHHHHHHTccEEEEEEEccHHHHTTTcTccTTGGGTTTTcccEEEccccGGGHHHHHHHHHHHHHccccccEEEEEEGGGTTccccGGGGGGTTcccccccccccHHHHHHHHHHHHHccccEEEEcHHHHHHTcHHHHHHHHHHHTccEEccccccccccTTcTTEEEEcccGcHHHHHHHHTTccEEEEEcccTTcccccccccccTTcEEEEEEccHHHHHHcccccEEEEccHHHHHHHHHHHccTTccccccHHHHHcccccccccccccccccccccccccHHHHHHHHHHHccTTcEEEEEcGGGHHHHHHHcccccTTcEEEcTTTcccccHHHHHHHHHHHcTTccEEEEEEHHHHTTTGGGHHHHHHHTcccEEEEEEccccHHHHHHHHHTTccccccccccccccGGGTTcccccHHHHHHHTTcEEEEEccHHHHHHHHHHHHHGccccEEEEEEcccccccTTTTcTTccGGGccccccHHHHccHHHH DISOP:02AL 1-3, 583-589| PSIPRED ccccccHHHHHHHHHHHccccEEEEcccccHHHHHHHHHHccccEEEEEccHHHHHHHHHHHHHHcccEEEEEEcccHHHHHHHHHHHHHHHccccEEEEEccccHHHccccccccccHHHHHHHHHEEEEEEccHHHHHHHHHHHHHHHHcccccEEEEEEccHHHccccccccccccccccccccccccHHHHHHHHHHHHHccccEEEEccccccHHHHHHHHHHHHHccccEEEcHHcccccccccccccccccccccHHHHHHHHcccEEEEEcccccccccccccccccccEEEEEEccHHccccEEcccccEEEcHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHccccccccccccccHHHHHHHHHHHcccccEEEEcccHHHHHHHHHHccccccEEEEccccccHHHHHHHHHHHHHHccccEEEEEEEcHHHHccHHHHHHHHHccccEEEEEEEcccccHHHHHHHHHcccccccccccccccccccccccccHHHHHHHccccEEEEccHHHHHHHHHHHHHcccccEEEEEEEcccccccccccccccHHHHHccHHHHHHHHHccc //