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Thermobifida fusca YX (tfus0)
Gene : AAZ54787.1
DDBJ      :             4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
Swiss-Prot:ISPG_THEFY   RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase;         EC=1.17.7.1;AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase;

Homologs  Archaea  0/68 : Bacteria  736/915 : Eukaryota  25/199 : Viruses  0/175   --->[See Alignment]
c.1.21d.134.1
:385 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   221->319 1xzfA PDBj 6e-04 26.8 %
:RPS:PDB   24->319 3e59B PDBj 3e-41 15.7 %
:RPS:PDB   333->377 3ecpA PDBj 8e-04 13.3 %
:RPS:SCOP  18->265 1q7mA1  c.1.21.2 * 5e-22 8.4 %
:RPS:SCOP  270->366 1aopA4  d.134.1.1 * 2e-08 20.8 %
:HMM:SCOP  23->217 1q7zA1 c.1.21.2 * 6.9e-10 25.6 %
:HMM:SCOP  272->360 1aopA4 d.134.1.1 * 2.9e-10 34.1 %
:RPS:PFM   21->360 PF04551 * GcpE 4e-88 52.4 %
:HMM:PFM   21->361 PF04551 * GcpE 5.2e-137 55.2 339/359  
:BLT:SWISS 1->385 ISPG_THEFY 0.0 100.0 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ54787.1 GT:GENE AAZ54787.1 GT:PRODUCT 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase GT:DATABASE GIB00263CH01 GT:ORG tfus0 GB:ACCESSION GIB00263CH01 GB:LOCATION 883104..884261 GB:FROM 883104 GB:TO 884261 GB:DIRECTION + GB:PRODUCT 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase GB:PROTEIN_ID AAZ54787.1 GB:DB_XREF GI:71914885 InterPro:IPR004588 LENGTH 385 SQ:AASEQ MSVDLGMPVAPPQPLAPRRKTRQVMVGNVPVGGDAPISVQSMTTTVTADINATLQQIAELTAAGCQIVRVAVPSADDAEALPIIAKKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIKKFDDKVGEIAKAASEAGIPIRIGVNAGSLDKRLLAKYGKATAEALVESALWECSLFEEHGFHDIKISVKHHDPVVMIRAYRMLAERCDYPLHLGVTEAGPAFQGTIKSAVAFGALLAEGIGDTIRVSLSAPPAEEVKVGIQILESLGLRQRGLEIVSCPSCGRAQVDVYTLANRVTAGLEGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPESQIVETLIEEALRIAEEMRAEGVPSGQPSVDVAG GT:EXON 1|1-385:0| SW:ID ISPG_THEFY SW:DE RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; EC=1.17.7.1;AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; SW:GN Name=ispG; OrderedLocusNames=Tfu_0749; SW:KW 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Isoprene biosynthesis;Metal-binding; Oxidoreductase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->385|ISPG_THEFY|0.0|100.0|385/385| GO:SWS:NREP 6 GO:SWS GO:0051539|"GO:4 iron, 4 sulfur cluster binding"|4Fe-4S| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0008299|"GO:isoprenoid biosynthetic process"|Isoprene biosynthesis| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| BL:PDB:NREP 1 BL:PDB:REP 221->319|1xzfA|6e-04|26.8|97/197| RP:PDB:NREP 2 RP:PDB:REP 24->319|3e59B|3e-41|15.7|281/305| RP:PDB:REP 333->377|3ecpA|8e-04|13.3|45/458| RP:PFM:NREP 1 RP:PFM:REP 21->360|PF04551|4e-88|52.4|334/353|GcpE| HM:PFM:NREP 1 HM:PFM:REP 21->361|PF04551|5.2e-137|55.2|339/359|GcpE| GO:PFM:NREP 3 GO:PFM GO:0016114|"GO:terpenoid biosynthetic process"|PF04551|IPR004588| GO:PFM GO:0046429|"GO:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"|PF04551|IPR004588| GO:PFM GO:0055114|"GO:oxidation reduction"|PF04551|IPR004588| RP:SCP:NREP 2 RP:SCP:REP 18->265|1q7mA1|5e-22|8.4|239/259|c.1.21.2| RP:SCP:REP 270->366|1aopA4|2e-08|20.8|96/145|d.134.1.1| HM:SCP:REP 23->217|1q7zA1|6.9e-10|25.6|180/0|c.1.21.2|1/1|Dihydropteroate synthetase-like| HM:SCP:REP 272->360|1aopA4|2.9e-10|34.1|88/145|d.134.1.1|1/1|Sulfite reductase hemoprotein (SiRHP), domains 2 and 4| OP:NHOMO 788 OP:NHOMOORG 761 OP:PATTERN -------------------------------------------------------------------- 111121111111-111111-1111211111111111111111111111111111111111111111122111111111111111111111111111---------1111111111111111111111111111111-----111-11111111111111111111111111111111111111111111111111111111111111111111111111111-11-111--111-----------------------------------------------------------------------------------------1111111111111111111111111111111111111111111111111-111111111111111111111111111111111111-11111111111-11111111111111111111111111111111111111111111111111111---------------111111111111111111111111111111111111111111111111111111111111111111111111111211111-111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111--11111--11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111-111---------1111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111--------11------------1------1------1111111111111 11------1---------------------------------------------------------------------------------------------------3-------------------------------------------------1---------------11111F111113122-2111----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 375 STR:RPRED 97.4 SQ:SECSTR ##EEEEHHHTcGHHHHHHHHHHHHHHHHHHHHHTTccccccHHHHHHHHHHHHHHHHHHHHHHTEEEcccccccccTTTcccccccHHHHHHHHHHHHHHHHHHTTcTTcEEEEEEccHHHHHHGGGGTccHHHHHHHHHHHHHHHHHTTcTTEEEEcGGGcGGGGGGcHHHHHHHHHHHHcccHHHHHHHHTTcHHHHHHHHHHHHHHHHHccTTccccHHHHHHHHHHHHHHHHHHHHHcTTcEEEEcccccTTccEEEccccTTccccccGGGcEEEEETTEEEEEcHHHHHHTTcHHccHHHHHTTTcEEEEETTTTcGGGccEEEEEEEETTEETTccccHHHHHHHHHHHHHHHHHHHHHHHHHHTTcccc######## DISOP:02AL 1-7, 370-378, 384-385| PSIPRED ccccccccccccccccccccccEEEEEEEEEcccccEEEEEEcccccccHHHHHHHHHHHHHHcccEEEEEcccHHHHHHHHHHHHcccccEEEEEcccHHHHHHHHHHHccEEEcccccccHHHHHHHHHHHHHHHccccEEEEcccccHHHHHHHHHccccHHHHHHHHHHHHHHHHHccccEEEEEEEEccHHHHHHHHHHHHHHccccEEEEEEccccccccHHHHHHHHHHHHHHccccEEEEEEccccHHHHHHHHHHHHHHcccccccEEEEccccccccccHHHHHHHHHHHHcccccccEEEEEEEEEccccccccccEEEEcccccEEEEEccEEEEEccHHHHHHHHHHHHHHHHHHHHHccccccccEEEEcc //