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Thermobifida fusca YX (tfus0)
Gene : AAZ56103.1
DDBJ      :             alanyl-tRNA synthetase
Swiss-Prot:SYA_THEFY    RecName: Full=Alanyl-tRNA synthetase;         EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase;         Short=AlaRS;

Homologs  Archaea  68/68 : Bacteria  907/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
a.203.1b.43.3d.104.1d.67.1
:889 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->468 1yfrA PDBj e-111 49.5 %
:BLT:PDB   516->693 1nyrB PDBj 2e-07 21.3 %
:RPS:PDB   4->439 2cvsA PDBj 3e-65 10.6 %
:RPS:PDB   462->709 2e1bA PDBj 3e-39 26.4 %
:RPS:PDB   683->820 3c9iF PDBj 8e-09 10.4 %
:RPS:SCOP  1->248 1riqA2  d.104.1.1 * e-111 57.8 %
:RPS:SCOP  249->470 1riqA1  a.203.1.1 * 3e-55 36.2 %
:RPS:SCOP  462->562 2e1bA1  b.43.3.6 * 4e-15 27.1 %
:RPS:SCOP  562->741 1nyqA3  d.67.1.1 * 1e-32 20.1 %
:HMM:SCOP  1->248 1riqA2 d.104.1.1 * 2.1e-92 63.0 %
:HMM:SCOP  249->472 1riqA1 a.203.1.1 * 6.5e-62 45.2 %
:HMM:SCOP  562->733 1nyrA3 d.67.1.1 * 7.5e-43 41.4 %
:RPS:PFM   5->566 PF01411 * tRNA-synt_2c e-159 54.7 %
:RPS:PFM   663->705 PF07973 * tRNA_SAD 9e-08 46.5 %
:HMM:PFM   5->565 PF01411 * tRNA-synt_2c 9.4e-204 52.8 542/551  
:HMM:PFM   663->706 PF07973 * tRNA_SAD 2.3e-17 52.3 44/44  
:HMM:PFM   816->884 PF02272 * DHHA1 1.3e-09 30.2 63/68  
:BLT:SWISS 1->889 SYA_THEFY 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ56103.1 GT:GENE AAZ56103.1 GT:PRODUCT alanyl-tRNA synthetase GT:DATABASE GIB00263CH01 GT:ORG tfus0 GB:ACCESSION GIB00263CH01 GB:LOCATION complement(2423584..2426253) GB:FROM 2423584 GB:TO 2426253 GB:DIRECTION - GB:PRODUCT alanyl-tRNA synthetase GB:PROTEIN_ID AAZ56103.1 GB:DB_XREF GI:71916201 InterPro:IPR002318 InterPro:IPR006193 LENGTH 889 SQ:AASEQ MKSAEIARRFLAFFEKNGHTVVPSASLIAEDPTLLLVNAGMVPFKPYFLGQRTPPYPRATSVQKCVRTIDIDEVGKTTRHASFFQMLGNFSFGDYFKEKAIPLAWELLTTSVADGGFGFDPERLWVTVYLDDDEAATIWREKVGLPEERIQRRGKADNFWSMGVPGPCGPCSEIYFDRGPEYGAEGGPVADEDRYLEVWNLVFMQFERGEGSGKEDYPILGELPSKNIDTGMGLERMAAILQGVDNIYETDTLGRILRRAAELTGTTYGENERADVSLRVIADHVRTATMLVADGVRPGNEKRGYVLRRILRRSIRNLRLLSGDESFHMHDLTAVAIDAMGDQYPELRADADKIHSIIDAEEKNFADTLRAGTTLFNRAVRRTKETGGTVFSGADAFQLHDTYGFPIDLTLEMAAEHGLKVDEETFHQLMQRQRETAKRDAQAKKLGNADISVYGNLLETGGPTEFLGYTDSESEARVLGIIVNGESTGAARKGDQVELVLDRTPFYAESGGQLADKGTITVDGRGVVDVEDVQKPIQGLFVHRGTVREGEVVVDDTVHAAIDTGRRASVSRSHSATHLIHSALRNTLGPSAGQAGSENQPGRLRFDFTSDKPLDATEIAQVEEEVNEVLARNIEVQYLETTLDEALRMGALAMFGEKYGNRVRVVDMTEYSRELCGGTHVAATGQLGLVKVLGESSVGSGVRRVEALVGLDALRRVSTESALVGQLSEQLKAPREELPQRIDSLVSRLRAAEKEIERLRAAQVLQAAGKLAESARDHGNSRVVTHRVEDGTTADDMRKLALDVRGRLGEDRPAVVAIAGVPSDRPVVVVAINKEAQQAGLKAGELVGVAARALGGGGGGRPDIAQGGGSDVTAIDTALRLVEQRVAGS GT:EXON 1|1-889:0| SW:ID SYA_THEFY SW:DE RecName: Full=Alanyl-tRNA synthetase; EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase; Short=AlaRS; SW:GN Name=alaS; OrderedLocusNames=Tfu_2070; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Protein biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->889|SYA_THEFY|0.0|100.0|889/889| GO:SWS:NREP 6 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| SEG 307->322|lrrilrrsirnlrlls| SEG 522->533|vdgrgvvdvedv| SEG 843->869|agelvgvaaralggggggrpdiaqggg| BL:PDB:NREP 2 BL:PDB:REP 1->468|1yfrA|e-111|49.5|438/448| BL:PDB:REP 516->693|1nyrB|2e-07|21.3|174/637| RP:PDB:NREP 3 RP:PDB:REP 4->439|2cvsA|3e-65|10.6|425/657| RP:PDB:REP 462->709|2e1bA|3e-39|26.4|212/216| RP:PDB:REP 683->820|3c9iF|8e-09|10.4|135/221| RP:PFM:NREP 2 RP:PFM:REP 5->566|PF01411|e-159|54.7|539/546|tRNA-synt_2c| RP:PFM:REP 663->705|PF07973|9e-08|46.5|43/44|tRNA_SAD| HM:PFM:NREP 3 HM:PFM:REP 5->565|PF01411|9.4e-204|52.8|542/551|tRNA-synt_2c| HM:PFM:REP 663->706|PF07973|2.3e-17|52.3|44/44|tRNA_SAD| HM:PFM:REP 816->884|PF02272|1.3e-09|30.2|63/68|DHHA1| GO:PFM:NREP 11 GO:PFM GO:0000166|"GO:nucleotide binding"|PF01411|IPR018164| GO:PFM GO:0004813|"GO:alanine-tRNA ligase activity"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF01411|IPR018164| GO:PFM GO:0005737|"GO:cytoplasm"|PF01411|IPR018164| GO:PFM GO:0006412|"GO:translation"|PF01411|IPR018164| GO:PFM GO:0006419|"GO:alanyl-tRNA aminoacylation"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF07973|IPR012947| GO:PFM GO:0005737|"GO:cytoplasm"|PF07973|IPR012947| GO:PFM GO:0006412|"GO:translation"|PF07973|IPR012947| GO:PFM GO:0016876|"GO:ligase activity, forming aminoacyl-tRNA and related compounds"|PF07973|IPR012947| GO:PFM GO:0043039|"GO:tRNA aminoacylation"|PF07973|IPR012947| RP:SCP:NREP 4 RP:SCP:REP 1->248|1riqA2|e-111|57.8|230/236|d.104.1.1| RP:SCP:REP 249->470|1riqA1|3e-55|36.2|210/212|a.203.1.1| RP:SCP:REP 462->562|2e1bA1|4e-15|27.1|85/87|b.43.3.6| RP:SCP:REP 562->741|1nyqA3|1e-32|20.1|169/179|d.67.1.1| HM:SCP:REP 1->248|1riqA2|2.1e-92|63.0|230/0|d.104.1.1|1/1|Class II aaRS and biotin synthetases| HM:SCP:REP 249->472|1riqA1|6.5e-62|45.2|221/0|a.203.1.1|1/1|Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)| HM:SCP:REP 562->733|1nyrA3|7.5e-43|41.4|169/179|d.67.1.1|1/1|ThrRS/AlaRS common domain| OP:NHOMO 1469 OP:NHOMOORG 1170 OP:PATTERN 11212121222222122121222121112221111111111111111122222121223232113111 2221211111111111111-1111111111111111111111111111111111111111111111112211-111111111111111111111111-111111111121111111111111111111111111111221111112111111111111111111112111111111111111111211121111333331132222222112211222111212211111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122211111111111111111112111121111111121111111211112111111111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1112111111111111111111111111111122221121222211112111111211112111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111112222212111111 1111241-31121111111-111112211111111111111111111111212222111111111111-2111111111111111111-12111111111111223123133732732221333242228L313222222322421223142223322233222332322222222222I2221332441232223222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 818 STR:RPRED 92.0 SQ:SECSTR cccHHHHHHHHHHHHTcccEEEEcTTcccTTcccccccccHHHHHHHHHHHHHHEcTTcTTHHHHHTcccccccccccccccEEEccEEEEcHHHHHHHHTTcEEEEcTcTTGGGccHHHHHHHHHHHHHTEEEHHHHHHHHHHHHHHHcccEEHTcTTTTTcccccccTTccccccccTTccEccccEEcHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHcccEEEEEcHHHHHHHTTccTTcHHHHHHHHHHHHHHHHHHHHHHcccTTcTTcGGGGTccTGGGGTccccccccHHHHHHHHHHHcccccccccccccTTTHHHHTTcccccccccHHHHHccEEcccEEcHHHHHHHHHTTcccHHHHHHHHHTTTcTcTTccHHHHHHTccTTcccHHHHHHHHHHHHTTccccccccEEcccccHHHHcccHTTccccEEEEEEEEEccGccccccTTccTTccEEEEEEETTEEEEEcccccccccccccccccccccTTcccccEEETTEEEEEEEEEEEEEccTTcccEEEEccGGGccccccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHTTTcEEEEccccccEEEEEEEcccccGGGGHHHHHHHHHHHHHHcccEEEEEccccccEEEEEEEEEEEHcTTccEEEEETTccEEcccccccccGGGTccEEEEEEEEEETTEEEEEEEEHTTHHHHHHHHHHHHHHHHHHHHHcccccEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH##HHHHHHHHHHHHHHHHHHHHHHHHHHH##################################################################### DISOP:02AL 1-2, 382-388, 432-447| PSIPRED ccHHHHHHHHHHHHHHcccEEEcccccccccccEEEEEccHHccccccccccccccccEEccccccccccHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccHHHEEEEEEcccHHHHHHHHHHccccHHHEEEccccccccccccccccccccEEEEEcccccccccccccccccEEEEEEEEEEEEEEcccccccccccccccccccccccccHHHHHHHHccccccHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEcHHHHHHHHHcccccHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHccccccccccEEccccEEEEEEEEccEEEcEEccccEEEEEEEccccccccccccccEEEEEEcccEEEEEEEEEEccccEEEEEEEEcccccccccEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHcccccEEcccEEccccEEEEEEccccccHHHHHHHHHHHHHHHHccccEEEEEccHHHHHHHccccccccccccEEEEEEEcccEEccccccccccccccccEEEEEEEEccccEEEEEEEEcHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEEcccccHHHHHHHHHHHHHHccccccEEEEEEEEccccEEEEEEEcHHHHcccccHHHHHHHHHHHHcccccccHHHcccccccHHHHHHHHHHHHHHHHcc //