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Thermotoga maritima MSB8 (tmar0)
Gene : AAD35194.1
DDBJ      :             DNA ligase
Swiss-Prot:DNLJ_THEMA   RecName: Full=DNA ligase;         EC=6.5.1.2;AltName: Full=Polydeoxyribonucleotide synthase [NAD+];

Homologs  Archaea  6/68 : Bacteria  899/915 : Eukaryota  61/199 : Viruses  2/175   --->[See Alignment]
a.60.2b.40.4c.15.1d.142.2
:688 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   23->668 1dgtB PDBj e-130 43.3 %
:RPS:PDB   23->668 1dgtB PDBj 0.0 46.2 %
:RPS:SCOP  23->319 1b04A  d.142.2.2 * 1e-79 53.2 %
:RPS:SCOP  318->403 1dgsA2  b.40.4.6 * 5e-16 57.0 %
:RPS:SCOP  406->588 1dgsA1  a.60.2.2 * 9e-36 41.9 %
:RPS:SCOP  593->669 1l7bA  c.15.1.2 * 5e-17 52.6 %
:HMM:SCOP  6->319 1b04A_ d.142.2.2 * 6.1e-122 57.4 %
:HMM:SCOP  318->403 1dgsA2 b.40.4.6 * 3.7e-30 60.5 %
:HMM:SCOP  404->588 1dgsA1 a.60.2.2 * 7.4e-59 54.1 %
:HMM:SCOP  588->677 1l7bA_ c.15.1.2 * 7.9e-20 38.2 %
:RPS:PFM   24->319 PF01653 * DNA_ligase_aden 3e-91 57.1 %
:RPS:PFM   321->396 PF03120 * DNA_ligase_OB 3e-19 59.2 %
:RPS:PFM   597->664 PF00533 * BRCT 5e-10 49.3 %
:HMM:PFM   9->319 PF01653 * DNA_ligase_aden 8.3e-128 55.3 311/315  
:HMM:PFM   322->401 PF03120 * DNA_ligase_OB 4.9e-37 63.8 80/82  
:HMM:PFM   593->664 PF00533 * BRCT 2.8e-18 40.8 71/78  
:HMM:PFM   536->565 PF00633 * HHH 4.9e-09 46.7 30/30  
:HMM:PFM   408->435 PF03119 * DNA_ligase_ZBD 2.7e-10 51.9 27/28  
:HMM:PFM   518->543 PF01367 * 5_3_exonuc 0.00044 38.5 26/101  
:BLT:SWISS 1->688 DNLJ_THEMA 0.0 100.0 %
:PROS 120->149|PS01055|DNA_LIGASE_N1
:PROS 332->347|PS01056|DNA_LIGASE_N2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAD35194.1 GT:GENE AAD35194.1 GT:PRODUCT DNA ligase GT:DATABASE GIB00025CH01 GT:ORG tmar0 GB:ACCESSION GIB00025CH01 GB:LOCATION complement(103127..105193) GB:FROM 103127 GB:TO 105193 GB:DIRECTION - GB:PRODUCT DNA ligase GB:NOTE similar to GB:AE000657 percent identity: 68.80; identified by sequence similarity; putative GB:PROTEIN_ID AAD35194.1 GB:DB_XREF GI:4980590 LENGTH 688 SQ:AASEQ MSERKIPKEVIEEVERLREEIEYHNYRYYVLNDPVITDEEYDRLMRRLIELERMYPELVTPDSPTQRVGGKVLEGFKTVKHSVPMLSLDNTYNEEEILEFDRRVKKALQEAEVEYVAELKIDGVSIALRYENGRFVLGATRGDGIEGEDVSENVKTVRSIPLRLRKPVTIEVRGEIYMPVDEFKRLNDEREEEGLPPFANPRNAAAGTLRQLNTALVAARRLDSFIYYVVHPENYGLKTQWEALQFLKELGFKVNPHSRLCKNIQEVIDYWKEWKERKRELDYWVDGVVVKVNRFDFQRILGETSKAPRWAIAFKFPAEQARTRVLDVTIQVGRTGVLTPVAELEPVQLAGTIVKRASLHNFEYIREKDIRIGDYVFVEKAGGIIPQIVKSIPELRTGNEKEIKPPDKCPVCGGKVGKLNPDEVAIRCLNPHCPAKLKRALRTLVSREALDIEGLGEKLIDRLVDAGLIKDIADIFYLTPFDLAQLGPGIGQRTIAKILQEIEEAKKRPLHKLITGLGIPMVGQKTAKILAEHFKSLEAIADASYETLKDIPGIGPEIAKSIVEYFRNPKTREIIEKLKKAGVKLEEKVVKLDILRGLTFAVTGTLKNFTREEIIEFLEKLGAKVVNSVSRNTDYLIVGENPGSKYERAKMLKVKMMSEEEFLEFVRKRAELKGYNFDEIMRSWKEWS GT:EXON 1|1-688:0| SW:ID DNLJ_THEMA SW:DE RecName: Full=DNA ligase; EC=6.5.1.2;AltName: Full=Polydeoxyribonucleotide synthase [NAD+]; SW:GN Name=ligA; OrderedLocusNames=TM_0100; SW:KW Complete proteome; DNA damage; DNA repair; DNA replication; Ligase;Magnesium; Manganese; Metal-binding; NAD; Zinc. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->688|DNLJ_THEMA|0.0|100.0|688/688| GO:SWS:NREP 5 GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0006260|"GO:DNA replication"|DNA replication| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| PROS 120->149|PS01055|DNA_LIGASE_N1|PDOC00809| PROS 332->347|PS01056|DNA_LIGASE_N2|PDOC00809| SEG 9->22|evieeverlreeie| SEG 43->54|rlmrrlielerm| BL:PDB:NREP 1 BL:PDB:REP 23->668|1dgtB|e-130|43.3|637/660| RP:PDB:NREP 1 RP:PDB:REP 23->668|1dgtB|0.0|46.2|637/660| RP:PFM:NREP 3 RP:PFM:REP 24->319|PF01653|3e-91|57.1|296/314|DNA_ligase_aden| RP:PFM:REP 321->396|PF03120|3e-19|59.2|76/82|DNA_ligase_OB| RP:PFM:REP 597->664|PF00533|5e-10|49.3|67/76|BRCT| HM:PFM:NREP 6 HM:PFM:REP 9->319|PF01653|8.3e-128|55.3|311/315|DNA_ligase_aden| HM:PFM:REP 322->401|PF03120|4.9e-37|63.8|80/82|DNA_ligase_OB| HM:PFM:REP 593->664|PF00533|2.8e-18|40.8|71/78|BRCT| HM:PFM:REP 536->565|PF00633|4.9e-09|46.7|30/30|HHH| HM:PFM:REP 408->435|PF03119|2.7e-10|51.9|27/28|DNA_ligase_ZBD| HM:PFM:REP 518->543|PF01367|0.00044|38.5|26/101|5_3_exonuc| GO:PFM:NREP 5 GO:PFM GO:0003911|"GO:DNA ligase (NAD+) activity"|PF01653|IPR013839| GO:PFM GO:0003911|"GO:DNA ligase (NAD+) activity"|PF03120|IPR004150| GO:PFM GO:0006260|"GO:DNA replication"|PF03120|IPR004150| GO:PFM GO:0006281|"GO:DNA repair"|PF03120|IPR004150| GO:PFM GO:0005622|"GO:intracellular"|PF00533|IPR001357| RP:SCP:NREP 4 RP:SCP:REP 23->319|1b04A|1e-79|53.2|293/310|d.142.2.2| RP:SCP:REP 318->403|1dgsA2|5e-16|57.0|86/86|b.40.4.6| RP:SCP:REP 406->588|1dgsA1|9e-36|41.9|179/181|a.60.2.2| RP:SCP:REP 593->669|1l7bA|5e-17|52.6|76/92|c.15.1.2| HM:SCP:REP 6->319|1b04A_|6.1e-122|57.4|312/312|d.142.2.2|1/1|DNA ligase/mRNA capping enzyme, catalytic domain| HM:SCP:REP 318->403|1dgsA2|3.7e-30|60.5|86/86|b.40.4.6|1/1|Nucleic acid-binding proteins| HM:SCP:REP 404->588|1dgsA1|7.4e-59|54.1|181/181|a.60.2.2|1/1|RuvA domain 2-like| HM:SCP:REP 588->677|1l7bA_|7.9e-20|38.2|89/92|c.15.1.2|1/1|BRCT domain| OP:NHOMO 1094 OP:NHOMOORG 968 OP:PATTERN ------------------------1--11111------------------------------------ 1111111111111111-11-11111111111111112111111111111111121111111111211122111111111111111111111111111--1111111111111111111111111111111121111111111111111211121111111111111111111111---1211-21111--111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121222222112111111111111111111111111111111111111111111111111111111111111111111111111-11112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111211112111111112111111111111111111-11111-1111122221222222222222-222222222222222222122222221222222222221212211-1222211222222222222111111111111111121111111111111111111111111121111122222222222121111111111111111111111111111111111111111111111111111111111111111-11111111111111211111111111111121 -111111-------------------------------------------------------1----------------------------1-1111111----------1----1-1---11-12---------2--11--1-1111-1---2-21-124211111-111--11-1114111--212--1-11----- ----------------------------------------------------------------------------------------------------------------------------------------------------------------2---------1---- STR:NPRED 665 STR:RPRED 96.7 SQ:SECSTR ######################HHHHHHHTTccccccTTHHHHHHHHHHHHHHHcGGGccTTcGGGccTTcccccccEEEcccccccccEEccHHHHHHHHHTTcccHcccccEEEEEEEcccEEEEEEEETTEEEEEEEcccccEEEccHHHHTTcTTcccccccccEEEEEEEEEccHHHHHHHHHHHHTTTccccccHHHHHHHHHccccTHHHHccccEEEEEEEccccccccccHHHHHHHHHHHTccccccEEEEEHHHHHHHHHHHHHHTGGGccccccEEEEEEccGGGTTTccccccccccEEEEEccccEEEEEccEEEEEEcTTccEEEEEEEEEEEccccEEEEEEccccTTTTTTTccTTcEEEEEcTTccccEEEEEcTTcccccccccccccccTTTcccccccEEEccccccccTTcTTcHHHHHHHHccTTccccTTccHHHHHHHHTTTccccTTTTcccccHHHHTTccccccHHHHHHHHHHHTGGGccHHHHHHHHTcTTccTTHHHHHHHHHccHHHHHTccHHHHcccccccHHHHHHHHHHHHcHHHHHHHHHHHTTTcccccccccccTTcccccccccccccccTTHHHHcccccccccccccccccccccccTTTcccccccTTTccccccccccTTTTTccccGGGGEEcccHHHHHTH# DISOP:02AL 1-6, 669-678, 686-688| PSIPRED cccccccHHHHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHccccccccccccccccHHHccccccccccccccHHHcccHHHHHHHHHHHHHHHccccccEEEEEccccEEEEEEEEccEEEEEEEcccccccccHHHHHHHHHHHHHHcccccEEEEEEEEEEcHHHHHHHHHHHHHHcccccccHHHHHHHHHHHccccHHHHcccEEEEEEEccccccccccHHHHHHHHHHcccccccccEEEccHHHHHHHHHHHHHHcccccccccEEEEEEccHHHHHHHccccccccEEEEEEccccEEEEEEEEEEEEEEccEEEEEEEEEEEEEEccEEEEEEEcccHHHHHHcccccccEEEEEEccccccEEccccccccccccccccccccccccccEEEEcccccEEEEEcccccHHHHHHHHHHHHcccccccccccHHHHHHHHHccccccHHHHHcccHHHHHHHcccHHHHHHHHHHHHHHHHHcccHHHHHHHcccccccHHHHHHHHHHHccHHHHHHccHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccccEEEEEEccccccHHHHHHHHHHcccEEEEcccccccEEEEccccccHHHHHHHcccEEEcHHHHHHHHHHccccccccHHHHHHHHHccc //