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Thermotoga maritima MSB8 (tmar0)
Gene : AAD35265.1
DDBJ      :             adenosylhomocysteinase
Swiss-Prot:SAHH_THEMA   RecName: Full=Adenosylhomocysteinase;         EC=3.3.1.1;AltName: Full=S-adenosyl-L-homocysteine hydrolase;         Short=AdoHcyase;

Homologs  Archaea  67/68 : Bacteria  449/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
c.2.1c.23.12
:404 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->400 1li4A PDBj 5e-78 40.8 %
:RPS:PDB   4->404 3ce6A PDBj 1e-47 37.2 %
:RPS:SCOP  2->204 1a7aA2  c.23.12.3 * 6e-69 34.0 %
:RPS:SCOP  194->287 1hkuA1  c.2.1.4 * 2e-09 13.8 %
:RPS:SCOP  311->404 1a7aA2  c.23.12.3 * 2e-20 29.8 %
:HMM:SCOP  1->404 1a7aA2 c.23.12.3 * 2.4e-87 52.1 %
:RPS:PFM   4->400 PF05221 * AdoHcyase 1e-87 44.3 %
:HMM:PFM   3->400 PF05221 * AdoHcyase 2.7e-59 41.9 236/268  
:BLT:SWISS 1->404 SAHH_THEMA 0.0 100.0 %
:PROS 64->78|PS00738|ADOHCYASE_1
:PROS 196->212|PS00739|ADOHCYASE_2
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAD35265.1 GT:GENE AAD35265.1 GT:PRODUCT adenosylhomocysteinase GT:DATABASE GIB00025CH01 GT:ORG tmar0 GB:ACCESSION GIB00025CH01 GB:LOCATION 177762..178976 GB:FROM 177762 GB:TO 178976 GB:DIRECTION + GB:PRODUCT adenosylhomocysteinase GB:NOTE similar to GP:2738603 percent identity: 99.75; identified by sequence similarity; putative GB:PROTEIN_ID AAD35265.1 GB:DB_XREF GI:4980667 LENGTH 404 SQ:AASEQ MNTGEMKINWVSRYMPLLNKIAEEYSREKPLSGFTVGMSIHLEAKTAYLAITLSKLGAKVVITGSNPLSTQDDVAEALRSKGITVYARRTHDESIYRENLMKVLDERPDFIIDDGGDLTVISHTEREEVLENLKGVSEETTTGVRRLKALEETGKLRVPVIAVNDSKMKYLFDNRYGTGQSTWDAIMRNTNLLVAGKNVVVAGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPMKEAVKIADFVITASGNTDVLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEIAVEKFEARPNVTGYTLENGKTVFLLAEGRLVNLAAGDGHPVEIMDLSFALQIFAVLYLLENHRKMSPKVYMLPDEIDERVARMKLDSLGVKIDELTEKQRRYLRSWQ GT:EXON 1|1-404:0| SW:ID SAHH_THEMA SW:DE RecName: Full=Adenosylhomocysteinase; EC=3.3.1.1;AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase; SW:GN Name=ahcY; OrderedLocusNames=TM_0172; SW:KW Complete proteome; Cytoplasm; Hydrolase; NAD; One-carbon metabolism. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->404|SAHH_THEMA|0.0|100.0|404/404| GO:SWS:NREP 3 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0006730|"GO:one-carbon metabolic process"|One-carbon metabolism| PROS 64->78|PS00738|ADOHCYASE_1|PDOC00603| PROS 196->212|PS00739|ADOHCYASE_2|PDOC00603| TM:NTM 1 TM:REGION 337->359| SEG 208->221|grgialraaglgar| BL:PDB:NREP 1 BL:PDB:REP 4->400|1li4A|5e-78|40.8|397/430| RP:PDB:NREP 1 RP:PDB:REP 4->404|3ce6A|1e-47|37.2|401/486| RP:PFM:NREP 1 RP:PFM:REP 4->400|PF05221|1e-87|44.3|397/421|AdoHcyase| HM:PFM:NREP 1 HM:PFM:REP 3->400|PF05221|2.7e-59|41.9|236/268|AdoHcyase| GO:PFM:NREP 2 GO:PFM GO:0004013|"GO:adenosylhomocysteinase activity"|PF05221|IPR000043| GO:PFM GO:0006730|"GO:one-carbon metabolic process"|PF05221|IPR000043| RP:SCP:NREP 3 RP:SCP:REP 2->204|1a7aA2|6e-69|34.0|203/268|c.23.12.3| RP:SCP:REP 194->287|1hkuA1|2e-09|13.8|94/193|c.2.1.4| RP:SCP:REP 311->404|1a7aA2|2e-20|29.8|94/268|c.23.12.3| HM:SCP:REP 1->404|1a7aA2|2.4e-87|52.1|242/269|c.23.12.3|1/1|Formate/glycerate dehydrogenase catalytic domain-like| OP:NHOMO 990 OP:NHOMOORG 711 OP:PATTERN 11111111111111111111111211111111111111111111111111111111111111111-11 11112-111111-111111-11111-11111111111111122211--111-111-11--211-2121111----111--11211111111--1-----1-111111111---------------1111111111111111111111111111111111111111111111111111111111-----11-1---------------------------------------11------------------------------------------------------------------------------------------1--------------1---------1--1--11111111-211---11--1111111-1111111111111111111111111111-11111111111-2111111222111111113111111111111111111111111-----------------------------1111111111111111111111111111111111111111111111111111111111111111-------1111111111-111111111111111111111111111-------------------------1111-111-1-----------------11------1121-------------------------------------------111---------------------1------------------------2111111221112-----------------111111111111111111111-1111111------------------------11111111111111111-111111------------------------------------1-11111111111 1111211-411-1111111111111111111111111111121111111111111111111111111111111111111111111111-12111111111111112-13159578553233433673B2CU3144C3333423463333243262323326A33222422411421111I1111131621211221111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 402 STR:RPRED 99.5 SQ:SECSTR ##HHHHHHHHHHHHcHHHHHHHHHHTTTcTTTTcEEEEEccccHHHHHHHHHHHHTTcEEEEEcccTTcccHHcccccccccccEEccTTccHHHHHHHHHHHHTccccEEEEcccHHHHHHHHHHHHHHHHcccEEEccHHHHHHHHHHHHTTcccccEEEcTTcHHHHTTHHHHHHHHHHHHHHHHHHccccTTcEEEEEcccHHHHHHHHHHHHTTcEEEEEcccHHHHHHHHHTTcEEccHHHHGGGccEEEEcccccccccHHHHHHccTTcEEEEccccGGGccHHHHHHTTcEEEEETTEEEEEcTTTccEEEEEGGGccHHHHHcccccHHHHHHHHHHHHHHHHHHHHTGGGccccEEcccHHHHHHHHHHHHHHHTcccccccHHHHHHHTccT DISOP:02AL 1-3| PSIPRED ccHHHHHHHHHHHHcHHHHHHHHHHHHcccccccEEEEEEcccHHHHHHHHHHHHHccEEEEEEcccccccHHHHHHHHHcccEEEccccccHHHHHHHHHHHHcccccEEEEcHHHHHHHHHHccHHHHHHcEEEEccccHHHHHHHHHHHcccEEEEEEEcccccHHHcccccHHHHHHHHHHHHHHcccEEEccEEEEEcccHHHHHHHHHHHHcccEEEEEEcccccHHHHHHcccEEccHHHHHHHccEEEEccccccHHHHHHHHHcccccEEEEEccccHHHHHHHHHHHcccEEEccccccEEEEccccEEEEEEccEEEEEEEcccccEEEEHHHHHHHHHHHHHHHccccccccccEEccHHHHHHHHHHHHHHcccEEEcccHHHHHHHHccc //