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Thermotoga maritima MSB8 (tmar0)
Gene : AAD35642.1
DDBJ      :             carbamoyl-phosphate synthase, large subunit
Swiss-Prot:CARB_THEMA   RecName: Full=Carbamoyl-phosphate synthase large chain;         EC=6.3.5.5;AltName: Full=Carbamoyl-phosphate synthetase ammonia chain;

Homologs  Archaea  56/68 : Bacteria  841/915 : Eukaryota  191/199 : Viruses  0/175   --->[See Alignment]
a.92.1c.24.1c.30.1c.98.2d.142.1
:1099 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->1093 1bxrA PDBj 0.0 55.5 %
:RPS:PDB   1->1098 1a9xA PDBj 0.0 52.9 %
:RPS:SCOP  1->127 1a9xA3  c.30.1.1 * 2e-20 66.9 %
:RPS:SCOP  128->401 1a9xA5  d.142.1.2 * 6e-76 67.5 %
:RPS:SCOP  408->543 1a9xA1  a.92.1.1 * 1e-40 41.5 %
:RPS:SCOP  578->665 2iojA1  c.98.2.2 * 2e-14 13.8 %
:RPS:SCOP  646->878 1w93A3  d.142.1.2 * 3e-47 19.1 %
:RPS:SCOP  944->1093 1b93A  c.24.1.2 * 9e-19 15.0 %
:HMM:SCOP  4->130 1a9xA4 c.30.1.1 * 7.3e-50 62.8 %
:HMM:SCOP  128->401 1a9xA5 d.142.1.2 * 3.1e-110 55.5 %
:HMM:SCOP  395->542 1a9xA1 a.92.1.1 * 2.4e-55 54.7 %
:HMM:SCOP  543->663 1a9xA4 c.30.1.1 * 2.3e-52 61.2 %
:HMM:SCOP  661->943 1a9xA5 d.142.1.2 * 1.9e-102 57.2 %
:HMM:SCOP  944->1098 1a9xA2 c.24.1.1 * 3.3e-30 38.4 %
:RPS:PFM   6->123 PF00289 * CPSase_L_chain 9e-20 43.2 %
:RPS:PFM   128->333 PF02786 * CPSase_L_D2 9e-41 45.5 %
:RPS:PFM   414->534 PF02787 * CPSase_L_D3 1e-29 49.6 %
:RPS:PFM   545->656 PF00289 * CPSase_L_chain 2e-20 55.1 %
:RPS:PFM   661->861 PF02786 * CPSase_L_D2 3e-31 38.5 %
:RPS:PFM   972->1022 PF02142 * MGS 5e-05 41.2 %
:HMM:PFM   128->334 PF02786 * CPSase_L_D2 6.5e-73 46.6 204/211  
:HMM:PFM   661->863 PF02786 * CPSase_L_D2 1.6e-40 30.8 201/211  
:HMM:PFM   415->534 PF02787 * CPSase_L_D3 6.4e-51 56.7 120/121  
:HMM:PFM   6->123 PF00289 * CPSase_L_chain 2.4e-23 38.2 102/110  
:HMM:PFM   547->656 PF00289 * CPSase_L_chain 3.5e-24 39.6 96/110  
:HMM:PFM   965->1067 PF02142 * MGS 7.6e-18 40.9 88/95  
:BLT:SWISS 1->1099 CARB_THEMA 0.0 100.0 %
:PROS 164->178|PS00866|CPSASE_1
:PROS 697->711|PS00866|CPSASE_1
:PROS 297->304|PS00867|CPSASE_2
:PROS 826->833|PS00867|CPSASE_2
:REPEAT 2|6->390|545->932
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAD35642.1 GT:GENE AAD35642.1 GT:PRODUCT carbamoyl-phosphate synthase, large subunit GT:DATABASE GIB00025CH01 GT:ORG tmar0 GB:ACCESSION GIB00025CH01 GB:LOCATION complement(585525..588824) GB:FROM 585525 GB:TO 588824 GB:DIRECTION - GB:PRODUCT carbamoyl-phosphate synthase, large subunit GB:NOTE similar to GB:AE000782 percent identity: 78.50; identified by sequence similarity; putative GB:PROTEIN_ID AAD35642.1 GB:DB_XREF GI:4981072 LENGTH 1099 SQ:AASEQ MPKREDIKRILVIGSGPITIGQAAEFDYSGTQALKALKSAGYEVIIVNSNSATIMTDPEFSDAVYIEPLTVEFLEKIIEKERPDALLPTLGGQTALNLAVELAERGILDKYGVQLIGAKLESIKKAEDRELFKETMEKAGLEVLRSRLVNNLADALETAREFGYPVIIRPSFTLGGTGGGIAFNEEELRDIVTKGLIESPVHTVLIEESVLGWKEYELEVVRDGAGNFIVVCSIENLDPMGIHTGDSITVAPAQTLTDVEYQRMRDAAYKVIDAIGIETGGSNIQFALDPETGRMVVIEMNPRVSRSSALASKATGYPIAKVAALLAVGFTLDEIPNYITGKTMAAFEPSIDYVVVKIPRFQLEKFPGADPRLNTQMKSVGEVMAIGRTFKEALGKALRSLELDAAPKLDLEHIREHLANPTPERISYVFAAFRNGMDVEEVHELTKIDRWFLREMKACIELEEELKLKKFDVEILKKAKQWGYSDREIAEIWGVSEKEIRKMREDNRIFPVYKMVDTCAAEFEAQTPYYYSTYNGVENEAVPSDREKIMILGSGPNRIGQGIEFDYTNVHGVWSFQEEGYETIMVNSNPETVSTDYDTSDRLYFEPLTVEDVLEIVRNEKPKGVVVAFGGQTPLKIAKYLVEERVNIIGTSFESIEIAEDREKFAKLLKQIGLKCPPFGTASSVEEALRVAENLGYPVLVRPSYVLGGRAMAIVDTPQELEMYVKEAAVVSPGYPVLIDKFLEDAIELDVDVVSDGKYVWIAGLMEQIEEAGVHSGDSACVLPPVSLSEKLVEEIEETVYKLVKALKVVGVANIQLAVKDEEIYIIEANPRASRTVPFVSKAIGIPVARIAAKIMVGRNLPELLSEYFPYPTRPGVKVDKLGESEILPTPWPKMFSVKEVVIPFHKFPGTDVLLGPEMRSTGEVMGIGEDFAEAFAKAQIAAGNPLPTTGAILATVADKDKREAVPLLAHLADMGFEIYATRGTAKALQSHGVEVKVVPKVGEGRPDVIDLLEQGKISLVVITQSSDEPALVAVSHGKEPFKVEGRRTVGYMIRTTALKRKIPYLTTVESLRAAVAAIRKMKKGSIVKVRRLTDTWKM GT:EXON 1|1-1099:0| SW:ID CARB_THEMA SW:DE RecName: Full=Carbamoyl-phosphate synthase large chain; EC=6.3.5.5;AltName: Full=Carbamoyl-phosphate synthetase ammonia chain; SW:GN Name=carB; OrderedLocusNames=TM_0557; SW:KW Amino-acid biosynthesis; Arginine biosynthesis; ATP-binding;Complete proteome; Ligase; Magnesium; Manganese; Metal-binding;Nucleotide-binding; Pyrimidine biosynthesis; Repeat. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1099|CARB_THEMA|0.0|100.0|1099/1099| GO:SWS:NREP 7 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0006526|"GO:arginine biosynthetic process"|Arginine biosynthesis| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006221|"GO:pyrimidine nucleotide biosynthetic process"|Pyrimidine biosynthesis| PROS 164->178|PS00866|CPSASE_1|PDOC00676| PROS 697->711|PS00866|CPSASE_1|PDOC00676| PROS 297->304|PS00867|CPSASE_2|PDOC00676| PROS 826->833|PS00867|CPSASE_2|PDOC00676| NREPEAT 1 REPEAT 2|6->390|545->932| SEG 461->470|eleeelklkk| SEG 800->813|vyklvkalkvvgva| SEG 933->943|aeafakaqiaa| SEG 993->1005|gvevkvvpkvgeg| BL:PDB:NREP 1 BL:PDB:REP 1->1093|1bxrA|0.0|55.5|1052/1073| RP:PDB:NREP 1 RP:PDB:REP 1->1098|1a9xA|0.0|52.9|1042/1058| RP:PFM:NREP 6 RP:PFM:REP 6->123|PF00289|9e-20|43.2|102/102|CPSase_L_chain| RP:PFM:REP 128->333|PF02786|9e-41|45.5|202/207|CPSase_L_D2| RP:PFM:REP 414->534|PF02787|1e-29|49.6|121/123|CPSase_L_D3| RP:PFM:REP 545->656|PF00289|2e-20|55.1|98/102|CPSase_L_chain| RP:PFM:REP 661->861|PF02786|3e-31|38.5|200/207|CPSase_L_D2| RP:PFM:REP 972->1022|PF02142|5e-05|41.2|51/95|MGS| HM:PFM:NREP 6 HM:PFM:REP 128->334|PF02786|6.5e-73|46.6|204/211|CPSase_L_D2| HM:PFM:REP 661->863|PF02786|1.6e-40|30.8|201/211|CPSase_L_D2| HM:PFM:REP 415->534|PF02787|6.4e-51|56.7|120/121|CPSase_L_D3| HM:PFM:REP 6->123|PF00289|2.4e-23|38.2|102/110|CPSase_L_chain| HM:PFM:REP 547->656|PF00289|3.5e-24|39.6|96/110|CPSase_L_chain| HM:PFM:REP 965->1067|PF02142|7.6e-18|40.9|88/95|MGS| GO:PFM:NREP 12 GO:PFM GO:0003824|"GO:catalytic activity"|PF00289|IPR005481| GO:PFM GO:0008152|"GO:metabolic process"|PF00289|IPR005481| GO:PFM GO:0003824|"GO:catalytic activity"|PF02786|IPR005479| GO:PFM GO:0005524|"GO:ATP binding"|PF02786|IPR005479| GO:PFM GO:0008152|"GO:metabolic process"|PF02786|IPR005479| GO:PFM GO:0004086|"GO:carbamoyl-phosphate synthase activity"|PF02787|IPR005480| GO:PFM GO:0006807|"GO:nitrogen compound metabolic process"|PF02787|IPR005480| GO:PFM GO:0003824|"GO:catalytic activity"|PF00289|IPR005481| GO:PFM GO:0008152|"GO:metabolic process"|PF00289|IPR005481| GO:PFM GO:0003824|"GO:catalytic activity"|PF02786|IPR005479| GO:PFM GO:0005524|"GO:ATP binding"|PF02786|IPR005479| GO:PFM GO:0008152|"GO:metabolic process"|PF02786|IPR005479| RP:SCP:NREP 6 RP:SCP:REP 1->127|1a9xA3|2e-20|66.9|127/127|c.30.1.1| RP:SCP:REP 128->401|1a9xA5|6e-76|67.5|274/275|d.142.1.2| RP:SCP:REP 408->543|1a9xA1|1e-40|41.5|135/153|a.92.1.1| RP:SCP:REP 578->665|2iojA1|2e-14|13.8|87/120|c.98.2.2| RP:SCP:REP 646->878|1w93A3|3e-47|19.1|228/267|d.142.1.2| RP:SCP:REP 944->1093|1b93A|9e-19|15.0|133/148|c.24.1.2| HM:SCP:REP 4->130|1a9xA4|7.3e-50|62.8|121/0|c.30.1.1|1/2|PreATP-grasp domain| HM:SCP:REP 128->401|1a9xA5|3.1e-110|55.5|274/0|d.142.1.2|1/2|Glutathione synthetase ATP-binding domain-like| HM:SCP:REP 395->542|1a9xA1|2.4e-55|54.7|148/153|a.92.1.1|1/1|Carbamoyl phosphate synthetase, large subunit connection domain| HM:SCP:REP 543->663|1a9xA4|2.3e-52|61.2|121/0|c.30.1.1|2/2|PreATP-grasp domain| HM:SCP:REP 661->943|1a9xA5|1.9e-102|57.2|271/0|d.142.1.2|2/2|Glutathione synthetase ATP-binding domain-like| HM:SCP:REP 944->1098|1a9xA2|3.3e-30|38.4|138/0|c.24.1.1|1/1|Methylglyoxal synthase-like| OP:NHOMO 2245 OP:NHOMOORG 1088 OP:PATTERN ---1-2221111111211111111111111112233342222222222122222-1-----111--22 1111421122213121111-1111111111111111122212111121211331221122111122211111111111113215445422341211-1122124221222---------------33233333323222222221122122221122121112121122212122222122121112222235433333333333333344555333353525343333325122222222222222232243121111232324322221142312223331111111111111111111111111111111122222222123-23111223122224332222222-12212233244321211112-12122211122222332222323334444444444445-22222221433234433353344422432442444444411111111111112231112222211--11111111111112222122122233311112111111111111111112111222121112221133222111122212212111111113221312121111111111312332122222113223212111112222222221123211111212111111211111111121111111111-112111111111211111111111111-11111111111111111111111122211111111111111111111111111111111111111111111111222211321---1-11----1--122322112113133333334233323443222222222111111111112111112111111111111121222222----------1---------------------------1--11111132 12--115-311-12434443332333444433322233333333333333222233232222233223333343332-4233333333-33243242222221444-223B433234232223253261Ec4-6351222212311221252132423249A22321B13E31614132q4441171472222263243 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1095 STR:RPRED 99.6 SQ:SECSTR ccccccccEEEEEccccccTTccTHHHHHHHHHHHHHHHHTcEEEEEcccTTcGGGcGGGccEEEcccccHHHHHHHHHHHcccEEEccccHHHHHHHHHHHHHTTHHHHHTcEEccccHHHHHHHHcHHHHHHHHHHTTcccccEEEEccHHHHHHHHHHHcccEEEEETTccTTTTcEEEccHHHHHHHHHHHHHHcTTccEEEEEccTTcEEEEEEEEEcTTccEEEEEEEEEcccTTccGGGccEEEccccccHHHHHHHHHHHHHHHHHHTcccEEEEEEEEEcTTTccEEEEEEEccccHHHHHHHHHHcccHHHHHHHHHTTccGGGcccTTTTTcccccccccccEEEEEEEccGGGcTTccccccccccccEEEEEEEccHHHHHHHHHHHccccTTcTTHHHHHHHHHHTccTTHHHHHHHHHHTTccHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHTGGHHHHHHHHHTTccHHHHHHHTTccHHHHHHHHHHTTcccEEEEccccTTccccccEEEEEEccccccccccccccEEEEEccccccTTccHHHHHHHHHHHHHHHHTTcEEEEEcccTTccTTcTTcccEEEcccccHHHHHHHHHHHcccEEEccccTHHHHTTHHHHHHTTcccccccHHHHHHHHcHHHHHHHHHHHTcccccEEEcccHHHHHHHHHHHcccEEEEccEEEEccHHHHHHHHHHccEEEHHHHHHcTTcccEEEcccTTcEEEEEEEEEccccEEEEEEEEEcccTTccGGGccEEEccccccHHHHHHHHHHHHHHHHHTTccEEEEEEEEEccccEEEEEEEccccTTHHHHHHHHcccHHHHHHHHHTTccHHHHEEccccccccccEEEEEEEEETcccccccccEEEEEEEcGGGGcTTccccccccccccEEEEEEEccHHHHHHHHHHHTTcccccccEEEEEccGGGGTTHHHHHHHHHHTTcEEEEcHHHHHHHHTTTcccEEcccTTTccccHHHHHHHTcccEEEEccccHHH##EEccccH#TcccHHHHHHTHHHHHHHHHTTcEEEccHHHHHHHHHHHTccTTEEETccccHHHHHH# DISOP:02AL 1-4| PSIPRED ccccccccEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEcccHHHHHcccccccEEEEEcccHHHHHHHHHHHcccEEEEEcccccccHHHHHHHHHHHHHHcccEEEcccHHHHHHHHcHHHHHHHHHHcccccccccccccHHHHHHHHHHccccEEEEEcccccccccEEEccHHHHHHHHHHHHHHcccccEEEEEEccccEEEEEEEEEEccccEEEEccHHHccccccccccEEEEEccccccHHHHHHHHHHHHHHHHHccccEEcEEEEEEEEccccEEEEEEEccccccHHHHHHHHHcccHHHHHHHHHcccccccccccccccccEEEccccccccccccEEEcccccccccccccccccEEEEEEEcccHHHHHHHHHHHHHHcccccccHHHHHHHHcccccHHHHHHHHHHHccccHHHHHHHHcccHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHccccHHHHHHHHcccHHHHHHHHHHcccEEEEEEEccccccccccccEEEEEEcccccccccccccEEEEEcccccEEcccccHHHHHHHHHHHHHHcccEEEEEEccccccccHHHHccEEEEEcccHHHHHHHHHHHcccEEEEEcccccHHHHHHHHHHcccEEEcccHHHHHHHHcHHHHHHHHHHcccccccccccccHHHHHHHHHHccccEEEEEccccccccEEEEccHHHHHHHHHHHHHHcccccEEEEEEccccEEEEEEEEEEcccEEEEEcccccccccccEEEEEEEEccccccHHHHHHHHHHHHHHHHHcccEEEEEEEEEEEcccEEEEEEEcccccHHHHHHHHHcccHHHHHHHHHccccccHHHHHccccccccEEEEEEcccccccccccccEEEEEccccccccccccccEEcccEEccEEEEEEEccHHHHHHHHHHHcccccccccEEEEEEEcccHHHHHHHHHHHHHcccEEEEEHHHHHHHHHccccEEEEEccccccHHHHHHHHcccEEEEEEcccccccHHHHHHcccccccccccccccHHHHHHHHHccccEEEcHHHHHHHHHHHHHHccccccEEEEHHHHHcc //