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Thermotoga maritima MSB8 (tmar0)
Gene : AAD36118.1
DDBJ      :             histidinol dehydrogenase
Swiss-Prot:HISX_THEMA   RecName: Full=Histidinol dehydrogenase;         Short=HDH;         EC=1.1.1.23;

Homologs  Archaea  55/68 : Bacteria  713/915 : Eukaryota  120/199 : Viruses  0/175   --->[See Alignment]
c.82.1
:428 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   14->424 1kaeA PDBj 8e-64 36.6 %
:RPS:PDB   4->97 3dmqA PDBj 4e-06 15.9 %
:RPS:PDB   169->326 2bvcA PDBj 5e-24 11.6 %
:RPS:SCOP  10->428 1k75A  c.82.1.2 * 3e-41 35.5 %
:HMM:SCOP  7->430 1k75A_ c.82.1.2 * 9.3e-73 27.1 %
:RPS:PFM   23->424 PF00815 * Histidinol_dh e-105 50.0 %
:HMM:PFM   15->425 PF00815 * Histidinol_dh 1.8e-143 48.3 406/413  
:BLT:SWISS 1->428 HISX_THEMA 0.0 100.0 %
:PROS 225->257|PS00611|HISOL_DEHYDROGENASE
:TM
:COIL

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAD36118.1 GT:GENE AAD36118.1 GT:PRODUCT histidinol dehydrogenase GT:DATABASE GIB00025CH01 GT:ORG tmar0 GB:ACCESSION GIB00025CH01 GB:LOCATION complement(1056429..1057715) GB:FROM 1056429 GB:TO 1057715 GB:DIRECTION - GB:PRODUCT histidinol dehydrogenase GB:NOTE similar to GB:AL009126 percent identity: 68.52; identified by sequence similarity; putative GB:PROTEIN_ID AAD36118.1 GB:DB_XREF GI:4981582 LENGTH 428 SQ:AASEQ MILMNNPGDKEVLRLLKQRMESVSQVEETVKEIIRRVKEEGDRALEEFLKRFEKHPVGIENLRVTEKEISEAQVEEEFVETIKIVIEDLKEFHRRQEERSFFFTTKGGSFLGEMVVPLESVGIYVPGGKVPYFSTLLMCAVPAIVAGVERIAVTTPPNENGGISPYILKTCEILGLKEIYRMGGAHAVAALTYGTETVKPVDKIVGPGGVFVTLAKKHVYGDVGIDSIAGPSEIAIVTDGSADLDLIAADFLSQAEHDENAMSVVITTSKEVFEKLPQVIERHLEALPEERRKTARISTENFGTIILTDSLKRAFEISNLIAPEHLEVLVENPFEPLGHIKNAGSVFLGKYTCESVGDYGAGPNHVLPTFRSARFSSGLRVSDFTKKIFITHLSEEDFRRKSELYSKMARWEGFEAHARAIDVRREKL GT:EXON 1|1-428:0| SW:ID HISX_THEMA SW:DE RecName: Full=Histidinol dehydrogenase; Short=HDH; EC=1.1.1.23; SW:GN Name=hisD; OrderedLocusNames=TM_1041; SW:KW Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis;Metal-binding; NAD; Oxidoreductase; Zinc. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->428|HISX_THEMA|0.0|100.0|428/428| GO:SWS:NREP 5 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0000105|"GO:histidine biosynthetic process"|Histidine biosynthesis| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| PROS 225->257|PS00611|HISOL_DEHYDROGENASE|PDOC00534| COIL:NAA 27 COIL:NSEG 1 COIL:REGION 13->39| TM:NTM 2 TM:REGION 107->129| TM:REGION 132->154| BL:PDB:NREP 1 BL:PDB:REP 14->424|1kaeA|8e-64|36.6|399/427| RP:PDB:NREP 2 RP:PDB:REP 4->97|3dmqA|4e-06|15.9|82/938| RP:PDB:REP 169->326|2bvcA|5e-24|11.6|147/475| RP:PFM:NREP 1 RP:PFM:REP 23->424|PF00815|e-105|50.0|398/412|Histidinol_dh| HM:PFM:NREP 1 HM:PFM:REP 15->425|PF00815|1.8e-143|48.3|406/413|Histidinol_dh| GO:PFM:NREP 4 GO:PFM GO:0000105|"GO:histidine biosynthetic process"|PF00815|IPR012131| GO:PFM GO:0004399|"GO:histidinol dehydrogenase activity"|PF00815|IPR012131| GO:PFM GO:0008270|"GO:zinc ion binding"|PF00815|IPR012131| GO:PFM GO:0051287|"GO:NAD or NADH binding"|PF00815|IPR012131| RP:SCP:NREP 1 RP:SCP:REP 10->428|1k75A|3e-41|35.5|408/431|c.82.1.2| HM:SCP:REP 7->430|1k75A_|9.3e-73|27.1|417/0|c.82.1.2|1/1|ALDH-like| OP:NHOMO 989 OP:NHOMOORG 888 OP:PATTERN ---1--1111111111-1111111111111111111111111111111111111-1-111-1----11 1111111111211111111-11111311111111111122111121111111112111--111111211111111111--11111111111111-----1-111111111---------------111111111111111111111222122211111111111211221111111111111111111111111111111111111111211111111111111111111111-11111111111111111-1----11-1---11--11----1-111-------111------------------------1----1----11-1111111-1-1111111---1-1--1111111112111111111--11111111-----111111111111111111111112111111211231-2111123212421111133321223131111111111111111-----------------------------21211111111122121111111112111111112122111111111111111121111111111111111111111-1211111111111-1111111111111111111111111111-1-------11111111111112111111111111111111111111--111111111111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111-1-----111111111111111-1111---1-11111111111111111121111111111--------111111111121111111111111111111111111111--------------------------------------1--1-111111 ------1-----11111212221232122111111111111111111111122232111111111111-1111111111111111111-11111111111111111-15-------------------------------------------------1----------------111181111121332231121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 420 STR:RPRED 98.1 SQ:SECSTR ###ccGGGTTTTHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHcccccGGHHHHHTTcccccTTEEHTHHHHHHHHHHHHHHHHHHHTccccEEEEEETTEEEEEEEEEccEEEEEccccccccTHHHHH#HHHHHHHTccEEEEEEcTTccHHHHHHHHcGGGccHHHHHHHHHHHHHHHHHHHHHcccTTHHHHccTTccccccccEEETcTccEEEccccccTEccccccccHHHHHHHHHHHHHHHHHTTccccccccccGGGccHHHHHTcccccHHHHccHHHHHHHHEEcccTHHHccHHHHGGGcccHHHEEEEEEcHHHGcccccccccccTTccccccHHHHTcHHHHHHHHTGGGTcTTccEEEEcHHHTTccccHHHHHHHHHHHHHHHHHTTcHHHHHHHHHH#### DISOP:02AL 1-7, 14-24| PSIPRED ccccccccHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHcccccEEEEcccEEEEEEEEEEccEEEEcccccccHHHHHHHHHHHHEEEcccEEEEEEcccccccccHHHHHHHHHHHHHHHHHHccHHHHHHHHHcccccccccEEEccccHHHHHHHHHHccccccccccccccEEEEEcccccHHHHHHHHHHHHHcccccEEEEEEccHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHcccEEEEEccHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHEEEEEcccccHHHHHHcccccccccccccHHccccccHHHHccEEEEEEEcHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHc //