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Thermotoga maritima MSB8 (tmar0)
Gene : AAD36833.1
DDBJ      :             1-deoxyxylulose-5-phosphate synthase
Swiss-Prot:DXS_THEMA    RecName: Full=1-deoxy-D-xylulose-5-phosphate synthase;         EC=2.2.1.7;AltName: Full=1-deoxyxylulose-5-phosphate synthase;         Short=DXP synthase;         Short=DXPS;

Homologs  Archaea  43/68 : Bacteria  804/915 : Eukaryota  119/199 : Viruses  0/175   --->[See Alignment]
c.23.10c.36.1c.48.1
:608 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->596 2o1xB PDBj e-112 42.8 %
:RPS:PDB   3->605 1ay0A PDBj 3e-72 17.9 %
:RPS:SCOP  4->257 1um9A  c.36.1.11 * 3e-25 10.9 %
:RPS:SCOP  241->456 2apjA1  c.23.10.7 * 3e-41 9.9 %
:RPS:SCOP  478->599 1dtwB2  c.48.1.2 * 1e-16 19.5 %
:HMM:SCOP  4->361 1w85A_ c.36.1.11 * 4.1e-68 33.4 %
:HMM:SCOP  279->461 1qgdA1 c.36.1.6 * 3.3e-57 41.3 %
:HMM:SCOP  471->601 1ik6A2 c.48.1.2 * 5.4e-24 31.2 %
:RPS:PFM   96->172 PF02775 * TPP_enzyme_C 1e-04 40.8 %
:RPS:PFM   306->459 PF02779 * Transket_pyr 7e-19 37.6 %
:RPS:PFM   481->591 PF02780 * Transketolase_C 3e-11 37.0 %
:HMM:PFM   298->460 PF02779 * Transket_pyr 1.2e-40 30.2 162/178  
:HMM:PFM   479->589 PF02780 * Transketolase_C 1.5e-26 32.7 110/124  
:HMM:PFM   97->169 PF02775 * TPP_enzyme_C 1.4e-09 28.4 67/150  
:BLT:SWISS 1->608 DXS_THEMA 0.0 100.0 %
:PROS 22->41|PS00801|TRANSKETOLASE_1
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAD36833.1 GT:GENE AAD36833.1 GT:PRODUCT 1-deoxyxylulose-5-phosphate synthase GT:DATABASE GIB00025CH01 GT:ORG tmar0 GB:ACCESSION GIB00025CH01 GB:LOCATION 1745882..1747708 GB:FROM 1745882 GB:TO 1747708 GB:DIRECTION + GB:PRODUCT 1-deoxyxylulose-5-phosphate synthase GB:NOTE similar to GB:U00096 SP:P77488 PID:1773104 PID:1786622 percent identity: 65.49; identified by sequence similarity; putative GB:PROTEIN_ID AAD36833.1 GB:DB_XREF GI:4982348 LENGTH 608 SQ:AASEQ MLLDEIKRMSYDELKRLAEDIRKRITEVVLKNGGHLASNLGTIELTLALYRVFDPREDAIIWDTGHQAYTHKILTGRDDLFHTIRTFGGLSGFVTRRESPLDWFGTGHAGTSIAAGLGFEKAFELLGEKRHVVVVIGDGALTSGMALEALNQLKNLNSKMKIILNDNGMSISPNVGGLAYHLSKLRTSPIYLKGKKVLKKVLEKTEIGFEVEEEMKYLRDSLKGMIQGTNFFESLGLKYFGPFDGHNIELLEKVFKRIRDYDYSSVVHVVTKKGKGFTAAEENPTKYHSASPSGKPKMLSYSELLGHTLSRVAREDKKIVAITAAMADGTGLSIFQKEHPDRFFDLGITEQTCVTFGAALGLHGMKPVVAIYSTFLQRAYDQIIHDVALQNAPVLFAIDRSGVVGEDGPTHHGLFDINYLLPVPNMKIISPSSPEEFVNSLYTVLKHLDGPVAIRYPKESFYGEVESLLENMKEIDLGWKILKRGREAAIIATGTILNEVLKIPLDVTVVNALTVKPLDTAVLKEIARDHDLIITVEEAMKIGGFGSFVAQRLQEMGWQGKIVNLGVEDLFVPHGGRKELLSMLGLDSEGLTKTVLTYIKARSREGKV GT:EXON 1|1-608:0| SW:ID DXS_THEMA SW:DE RecName: Full=1-deoxy-D-xylulose-5-phosphate synthase; EC=2.2.1.7;AltName: Full=1-deoxyxylulose-5-phosphate synthase; Short=DXP synthase; Short=DXPS; SW:GN Name=dxs; OrderedLocusNames=TM_1770; SW:KW Complete proteome; Isoprene biosynthesis; Thiamine biosynthesis;Thiamine pyrophosphate; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->608|DXS_THEMA|0.0|100.0|608/608| GO:SWS:NREP 3 GO:SWS GO:0008299|"GO:isoprenoid biosynthetic process"|Isoprene biosynthesis| GO:SWS GO:0009228|"GO:thiamin biosynthetic process"|Thiamine biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 22->41|PS00801|TRANSKETOLASE_1|PDOC00635| SEG 192->204|lkgkkvlkkvlek| BL:PDB:NREP 1 BL:PDB:REP 5->596|2o1xB|e-112|42.8|545/579| RP:PDB:NREP 1 RP:PDB:REP 3->605|1ay0A|3e-72|17.9|581/678| RP:PFM:NREP 3 RP:PFM:REP 96->172|PF02775|1e-04|40.8|71/139|TPP_enzyme_C| RP:PFM:REP 306->459|PF02779|7e-19|37.6|149/172|Transket_pyr| RP:PFM:REP 481->591|PF02780|3e-11|37.0|108/122|Transketolase_C| HM:PFM:NREP 3 HM:PFM:REP 298->460|PF02779|1.2e-40|30.2|162/178|Transket_pyr| HM:PFM:REP 479->589|PF02780|1.5e-26|32.7|110/124|Transketolase_C| HM:PFM:REP 97->169|PF02775|1.4e-09|28.4|67/150|TPP_enzyme_C| GO:PFM:NREP 4 GO:PFM GO:0003824|"GO:catalytic activity"|PF02775|IPR011766| GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF02775|IPR011766| GO:PFM GO:0003824|"GO:catalytic activity"|PF02780|IPR005476| GO:PFM GO:0008152|"GO:metabolic process"|PF02780|IPR005476| RP:SCP:NREP 3 RP:SCP:REP 4->257|1um9A|3e-25|10.9|238/331|c.36.1.11| RP:SCP:REP 241->456|2apjA1|3e-41|9.9|203/244|c.23.10.7| RP:SCP:REP 478->599|1dtwB2|1e-16|19.5|118/138|c.48.1.2| HM:SCP:REP 4->361|1w85A_|4.1e-68|33.4|305/0|c.36.1.11|1/1|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 279->461|1qgdA1|3.3e-57|41.3|179/195|c.36.1.6|1/1|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 471->601|1ik6A2|5.4e-24|31.2|128/135|c.48.1.2|1/1|TK C-terminal domain-like| OP:NHOMO 1637 OP:NHOMOORG 966 OP:PATTERN 22-1--1111111111-112111-2111-1-1---11111111-----------11-111-122--11 112361111111-121122-2111232122211111336312232123111163512211323242533211111111322221113222231111112233343334-5111111111111111221222222322331-111122211112221111111112133321212112111111211112213111111111111111111222211111111-21122211121--------------------2-----21-211111--1----2211111-11-111111111111111111111111-1-11111222121224333323343513332222113--3242222222232224312133131111112112113332121211311111111112-33333533221-2331233232331411122222332112222222223312222--1---------1----111---------11121222121422122222223322222212113121111111211112121221111111121111111111211122231111131111444343324223211131112111111111111111111111111121111121114222222222211122111--31111--11121222311111111111-111111111111111111333321111322222222222222211111111112212222222221111-----11111111111122111111111122222111112122221122211221221111111111-11111111122122222222211111111122223344--------211-----------1------1------2322223232122 12--11--411---111-1----1-11111111---1111-11111--111111111-11111-----------------------11----1------------1--21-2--1212-2123133252AV3-33412113125--21123114-112211-11-1-311---412221I2221265C8153-1----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 608 STR:RPRED 100.0 SQ:SECSTR ccccHHHHHHHHHHHHHHHHHHHHHHHHHHHTccccHHHHHHHHHHHHHHHTccTTccEEEEccGGGHHHHHHHTTccccHHTTTcTTccccccccTTcTTcccccccTTHHHHHHHHHHHHHHHHcccccEEEEEcHHHHHcHHHHHHHHHHHHTTcTTEEEEEEccEETTEEGGTccccHHHHHHHHTcEEEEEccTTTcHHHHHHHHTTcTTccEEEEEEccTTTTcTTTTcGGGTcccccHHHHHHHHHHTTccTTccccccHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHTHHTTTcTTEEEEEcccHHHHTcccccEETTccEEEccccHHHHHHHHHHHHHHcTTcEEEEEHHHHGGGHHHHHHHHHHTcccEEEEEcccGGGcTTcTTcccccHHHHHTcccccEEEccccHHHHHHHHHHHHHcccccEEEEccccccEEcccTTccHHHHTTccEEEccccccEEEEEcTTHHHHHHHHTccEEEEEcccHHHHHTccHHHHHHTTccEEEEccccccGGGGGTccEEEHHHcTccccEEEEccccccccccHHHHHHHHTccHHHHHHHHHHHHHHHTTcHHH DISOP:02AL 603-608| PSIPRED cccHHHHcccHHHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHcccccccEEEEEcccHHHHHHHHHccHHHHHHHHHcccccccccccccccEEEccccHHHHHHHHHHHHHHHHHHccccEEEEEEEccccccHHHHHHHHHHHHHcccEEEEEEcccEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHccccHHHHcccccccccccccHHHHHHHHHHHHHccccEEEEEEEHHHccccHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHcccEEEEEccccccccccHHHHcccccEEEcccHHHHHHHHHHHHHHccccEEEHHHHHHHHHHHHHHHHHHHHccccEEEEEccccEEccccHHHccccHHHHHHHHcccEEEEEccHHHHHHHHHHHHHcccccEEEEEcccccccccccccccccccccccEEEEccccEEEEEEHHHHHHHHHHcccEEEEEccccccccHHHHHHHHHHcccEEEEccccccccHHHHHHHHHHHccccccEEEEEEcccccccccHHHHHHHHcccHHHHHHHHHHHHHcccccccc //