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Thermus thermophilus HB27 (tthe0)
Gene : AAS80409.1
DDBJ      :             imidazoleglycerol-phosphate dehydratase
Swiss-Prot:HIS7_THET2   RecName: Full=Imidazoleglycerol-phosphate dehydratase;         Short=IGPD;         EC=4.2.1.19;

Homologs  Archaea  55/68 : Bacteria  713/915 : Eukaryota  117/199 : Viruses  0/175   --->[See Alignment]
d.14.1
:194 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   2->180 2f1dA PDBj 3e-39 44.6 %
:RPS:PDB   8->183 2ae8A PDBj 6e-36 36.4 %
:RPS:SCOP  1->84 1rhyA1  d.14.1.9 * 1e-25 44.9 %
:RPS:SCOP  87->182 1rhyA2  d.14.1.9 * 4e-16 33.0 %
:HMM:SCOP  1->86 2f1dA1 d.14.1.9 * 7.8e-31 57.0 %
:HMM:SCOP  87->182 1rhyA2 d.14.1.9 * 7.3e-27 46.2 %
:RPS:PFM   31->176 PF00475 * IGPD 6e-33 52.1 %
:HMM:PFM   31->176 PF00475 * IGPD 2.6e-57 54.9 144/145  
:BLT:SWISS 1->194 HIS7_THET2 e-111 100.0 %
:PROS 61->74|PS00954|IGP_DEHYDRATASE_1
:PROS 158->170|PS00955|IGP_DEHYDRATASE_2

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS80409.1 GT:GENE AAS80409.1 GT:PRODUCT imidazoleglycerol-phosphate dehydratase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION 54550..55134 GB:FROM 54550 GB:TO 55134 GB:DIRECTION + GB:PRODUCT imidazoleglycerol-phosphate dehydratase GB:PROTEIN_ID AAS80409.1 GB:DB_XREF GI:46195991 LENGTH 194 SQ:AASEQ MREATVERATAETWVRLRLGLDGPTGGKVDTGLPFLDHMLLQLQRHGRFLLEVEARGDLEVDVHHLVEDVGIALGMALKEALGDGVGLERYAEAFAPMDETLVLCVLDLSGRPHLEFRPEAWPVVGEAGGVNHYHLREFLRGLVNHGRLTLHLRLLSGREAHHVVEASFKALARALHKATRRTGEGVPSTKGVL GT:EXON 1|1-194:0| SW:ID HIS7_THET2 SW:DE RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD; EC=4.2.1.19; SW:GN Name=hisB; OrderedLocusNames=TT_C0061; SW:KW Amino-acid biosynthesis; Complete proteome; Cytoplasm;Histidine biosynthesis; Lyase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->194|HIS7_THET2|e-111|100.0|194/194| GO:SWS:NREP 4 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0000105|"GO:histidine biosynthetic process"|Histidine biosynthesis| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| PROS 61->74|PS00954|IGP_DEHYDRATASE_1|PDOC00738| PROS 158->170|PS00955|IGP_DEHYDRATASE_2|PDOC00738| BL:PDB:NREP 1 BL:PDB:REP 2->180|2f1dA|3e-39|44.6|177/183| RP:PDB:NREP 1 RP:PDB:REP 8->183|2ae8A|6e-36|36.4|165/166| RP:PFM:NREP 1 RP:PFM:REP 31->176|PF00475|6e-33|52.1|144/145|IGPD| HM:PFM:NREP 1 HM:PFM:REP 31->176|PF00475|2.6e-57|54.9|144/145|IGPD| GO:PFM:NREP 2 GO:PFM GO:0000105|"GO:histidine biosynthetic process"|PF00475|IPR000807| GO:PFM GO:0004424|"GO:imidazoleglycerol-phosphate dehydratase activity"|PF00475|IPR000807| RP:SCP:NREP 2 RP:SCP:REP 1->84|1rhyA1|1e-25|44.9|78/86|d.14.1.9| RP:SCP:REP 87->182|1rhyA2|4e-16|33.0|94/94|d.14.1.9| HM:SCP:REP 1->86|2f1dA1|7.8e-31|57.0|86/0|d.14.1.9|1/2|Ribosomal protein S5 domain 2-like| HM:SCP:REP 87->182|1rhyA2|7.3e-27|46.2|91/0|d.14.1.9|2/2|Ribosomal protein S5 domain 2-like| OP:NHOMO 913 OP:NHOMOORG 885 OP:PATTERN ---1--1111111111-1111111111111111111111111111111211111-1-111-1----11 1111111111111111111-11111111111111111111121111111111111111--111111111111111111--11111111111111-----1-111111111---------------111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111-1----11-1---11--11----1-111-------111------------------------1----1----11-1111111-1-1111111---1-1--1111111111111111111--11111111-----111111111111111111111111111111111111-1111111111111111111111111111111111111111111-----------------------------11111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111-1111111111111111111111111111-1-------11111111111111111111111111111111111111--111111111111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111-1-----111111111111111-1111---1111111111111111111111111111111--------111111111111111111111111111111111111111--------------------------------------1--1-111111 ------1-----221-111111112111111-1111-1111111111111111111111111111111111111-111--11111111-12111111111111111-11-------------------------------------------------1----2-1-------1-1111D111-111131312112111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 182 STR:RPRED 93.8 SQ:SECSTR #cEcEEEEEEEccEEEEEEEcccccccEEEcccHHHHHHHHHHHHHHccEEEEEEEccHTTcHHHHHHHHHHHHHHHHHHHHHHccccccEEEEEEEETTEEEEEEEEcccccEEEEEccccccccEETTEETTHHHHHHHHHHHHTTcEEEEEEEEcccHHHHHHHHHHHHHHHHHHHTccc########### PSIPRED cEEEEEEEEcccEEEEEEEEEcccEEEEEEccccHHHHHHHHHHHHccccEEEEEEEEEEEEccccHHHHHHHHHHHHHHHHcccccccEEEEEEEEHHHHEEEEEEEccccEEEEEEccccccccccccccHHHHHHHHHHHHHHcccEEEEEEEccccHHHHHHHHHHHHHHHHHHHccccccccccccccc //