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Thermus thermophilus HB27 (tthe0)
Gene : AAS80516.1
DDBJ      :             malate dehydrogenase
Swiss-Prot:MDH_THETH    RecName: Full=Malate dehydrogenase;         EC=1.1.1.37;

Homologs  Archaea  5/68 : Bacteria  266/915 : Eukaryota  132/199 : Viruses  0/175   --->[See Alignment]
c.2.1d.162.1
:327 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->327 1y7tA PDBj e-172 100.0 %
:RPS:PDB   1->327 1bmdA PDBj 3e-35 92.4 %
:RPS:SCOP  6->155 1b8pA1  c.2.1.5 * 5e-07 71.3 %
:RPS:SCOP  157->324 1b8pA2  d.162.1.1 * 1e-33 41.9 %
:HMM:SCOP  2->155 1b8pA1 c.2.1.5 * 6.9e-50 45.5 %
:HMM:SCOP  156->324 5mdhA2 d.162.1.1 * 1.1e-59 50.3 %
:RPS:PFM   6->142 PF00056 * Ldh_1_N 1e-15 43.8 %
:RPS:PFM   156->320 PF02866 * Ldh_1_C 1e-12 33.5 %
:HMM:PFM   156->323 PF02866 * Ldh_1_C 5.4e-49 33.9 165/174  
:HMM:PFM   5->153 PF00056 * Ldh_1_N 8e-44 38.3 141/142  
:BLT:SWISS 1->327 MDH_THETH e-171 100.0 %
:PROS 155->167|PS00068|MDH
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS80516.1 GT:GENE AAS80516.1 GT:PRODUCT malate dehydrogenase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION complement(149072..150055) GB:FROM 149072 GB:TO 150055 GB:DIRECTION - GB:PRODUCT malate dehydrogenase GB:PROTEIN_ID AAS80516.1 GB:DB_XREF GI:46196098 LENGTH 327 SQ:AASEQ MKAPVRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVILQLLEIPQAMKALEGVVMELEDCAFPLLAGLEATDDPKVAFKDADYALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEVAKKDVKVLVVGNPANTNALIAYKNAPGLNPRNFTAMTRLDHNRAKAQLAKKTGTGVDRIRRMTVWGNHSSTMFPDLFHAEVDGRPALELVDMEWYEKVFIPTVAQRGAAIIQARGASSAASAANAAIEHIRDWALGTPEGDWVSMAVPSQGEYGIPEGIVYSFPVTAKDGAYRVVEGLEINEFARKRMEITAQELLDEMEQVKALGLI GT:EXON 1|1-327:0| SW:ID MDH_THETH SW:DE RecName: Full=Malate dehydrogenase; EC=1.1.1.37; SW:GN Name=mdh; SW:KW 3D-structure; Direct protein sequencing; NAD; Oxidoreductase;Tricarboxylic acid cycle. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->327|MDH_THETH|e-171|100.0|327/327| GO:SWS:NREP 3 GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| GO:SWS GO:0006099|"GO:tricarboxylic acid cycle"|Tricarboxylic acid cycle| PROS 155->167|PS00068|MDH|PDOC00066| SEG 223->246|aqrgaaiiqargassaasaanaai| BL:PDB:NREP 1 BL:PDB:REP 1->327|1y7tA|e-172|100.0|327/327| RP:PDB:NREP 1 RP:PDB:REP 1->327|1bmdA|3e-35|92.4|327/327| RP:PFM:NREP 2 RP:PFM:REP 6->142|PF00056|1e-15|43.8|128/141|Ldh_1_N| RP:PFM:REP 156->320|PF02866|1e-12|33.5|161/169|Ldh_1_C| HM:PFM:NREP 2 HM:PFM:REP 156->323|PF02866|5.4e-49|33.9|165/174|Ldh_1_C| HM:PFM:REP 5->153|PF00056|8e-44|38.3|141/142|Ldh_1_N| GO:PFM:NREP 4 GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00056|IPR001236| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00056|IPR001236| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF02866|IPR001236| GO:PFM GO:0055114|"GO:oxidation reduction"|PF02866|IPR001236| RP:SCP:NREP 2 RP:SCP:REP 6->155|1b8pA1|5e-07|71.3|150/156|c.2.1.5| RP:SCP:REP 157->324|1b8pA2|1e-33|41.9|167/171|d.162.1.1| HM:SCP:REP 2->155|1b8pA1|6.9e-50|45.5|154/156|c.2.1.5|1/1|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 156->324|5mdhA2|1.1e-59|50.3|169/0|d.162.1.1|1/1|LDH C-terminal domain-like| OP:NHOMO 700 OP:NHOMOORG 403 OP:PATTERN ---------------------------------1-11----------------1-------1------ 1--11111111111-1111-11111-1111111---1111-11--1-11---1--11---1-111111111-----------1-----1111-111------1-------111111111111111-1------1------------1-1-111--------------1---------------11111------------------------------------------------------------111-1--------111------------------------------------------------------------------------------------------------1--------------11111-----111111--1211-----------------------1-----111-----23-1-1-------11--------1-----1---------1111-------------1-111-----111112111111111111111111-212111111111111111111211111----11-------1111111---1----------1111111--11111--1--------------------1------1----11--11----------------------1111--------------------------------------------------------------------------------------------1111111111111--111---1--------1111111111-1-------------------------------------1---11111111111111--1-111111-----------------------------------------------11 ----332-5211---11----11111111----2---------2121111111122-2-1-1-1-11-1-11--------1-----1-----1------1--11---1-34443252213212232231BF2-336222241223222222212123231-433212121813322224*4323586FC-64-13111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 327 STR:RPRED 100.0 SQ:SECSTR ccccEEEEEETTTcHHHHHHHHHHHTTTHHHTTcccEEEEEccGGGHHHHHHHHHHHHHHHcTTTcccEEEEccGGGGTTccEEEEcccccccTTccHHHHHHHHHHHHHHHHHHHHTHTccccEEEEccccHHHHHHHHHHTccccGGGEEEccHHHHHHHHHHHHHHHTTccTTTEEccEEEEcccccEEEcGGGcEETTccHHHccccHHHHHHHHHHHHTHHHHHHHHTTTccccHHHHHHHHHHHHHHHTcTcccEEEEEEEEEcGGGccEEEEEEEEEEEETTEEEEEccccccHHHHHHHHHHHHHHHHHHHHTcccTcc DISOP:02AL 1-3| PSIPRED cccccEEEEEccccHHHHHHHHHHHccccccccccEEEEEEEccccccHHHHHHHHHHcccccccccEEEccccHHHHccccEEEEEccccccccccHHHHHHHHHHHHHHHHHHHHHHcccccEEEEEcccHHHHHHHHHHHcccccccEEEEccHHHHHHHHHHHHHHHcccHHHcEEEEEEccccccEEEEEEEEEEccEEHHHHccHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHccccccEEEEEEEEcccccccccEEEEEEEEcccccEEEcccccccHHHHHHHHHHHHHHHHHHHHHHHcccc //