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Thermus thermophilus HB27 (tthe0)
Gene : AAS80590.1
DDBJ      :             biotin synthase
Swiss-Prot:BIOB_THET2   RecName: Full=Biotin synthase;         EC=2.8.1.6;AltName: Full=Biotin synthetase;

Homologs  Archaea  13/68 : Bacteria  665/915 : Eukaryota  112/199 : Viruses  0/175   --->[See Alignment]
c.1.28
:329 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   61->325 1r30B PDBj 1e-40 36.0 %
:RPS:PDB   40->296 1alaA PDBj 3e-22 9.1 %
:RPS:SCOP  41->325 1r30A  c.1.28.1 * 1e-65 33.5 %
:HMM:SCOP  13->325 1r30A_ c.1.28.1 * 2.3e-76 41.7 %
:RPS:PFM   230->321 PF06968 * BATS 5e-07 37.1 %
:HMM:PFM   230->322 PF06968 * BATS 7.4e-20 42.7 89/92  
:HMM:PFM   61->218 PF04055 * Radical_SAM 1.2e-18 25.7 152/166  
:BLT:SWISS 1->329 BIOB_THET2 e-154 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS80590.1 GT:GENE AAS80590.1 GT:PRODUCT biotin synthase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION 228534..229523 GB:FROM 228534 GB:TO 229523 GB:DIRECTION + GB:PRODUCT biotin synthase GB:PROTEIN_ID AAS80590.1 GB:DB_XREF GI:46196172 LENGTH 329 SQ:AASEQ MAWPDLDPPRLAERPLSLQEALFVLEAPPEALPALAEAAIRVKEYFFGRRLKLVRLLNVKSGFCPEDCAYCAQSARSQAAIARYPLLSLEEILERAEEAQRLSARRFCLVAALRGPTPKVLERLGEAAQAIKARFPLELCASLGLLEEGMAEALKAAGFDYYNHNLNTAPSLYPRIATTHTYQDRLWTLKRAREAGLKLCSGVILGMGEGPKEVYEMALALRELGVESLPVNFLLPIPGTPLGDGRTVAGLTPERALKALILFRLLNPKAELRASAGRERYLGPYEPLAFRMVNSIFLQGYLTQPGSPWERDRALWESLGLDVEEGACG GT:EXON 1|1-329:0| SW:ID BIOB_THET2 SW:DE RecName: Full=Biotin synthase; EC=2.8.1.6;AltName: Full=Biotin synthetase; SW:GN Name=bioB; OrderedLocusNames=TT_C0242; SW:KW 2Fe-2S; 4Fe-4S; Biotin biosynthesis; Complete proteome; Iron;Iron-sulfur; Metal-binding; S-adenosyl-L-methionine; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->329|BIOB_THET2|e-154|100.0|329/329| GO:SWS:NREP 6 GO:SWS GO:0051537|"GO:2 iron, 2 sulfur cluster binding"|2Fe-2S| GO:SWS GO:0051539|"GO:4 iron, 4 sulfur cluster binding"|4Fe-4S| GO:SWS GO:0009102|"GO:biotin biosynthetic process"|Biotin biosynthesis| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| SEG 25->39|leappealpalaeaa| SEG 49->60|rrlklvrllnvk| SEG 72->83|aqsarsqaaiar| SEG 143->158|lglleegmaealkaag| BL:PDB:NREP 1 BL:PDB:REP 61->325|1r30B|1e-40|36.0|261/313| RP:PDB:NREP 1 RP:PDB:REP 40->296|1alaA|3e-22|9.1|253/316| RP:PFM:NREP 1 RP:PFM:REP 230->321|PF06968|5e-07|37.1|89/93|BATS| HM:PFM:NREP 2 HM:PFM:REP 230->322|PF06968|7.4e-20|42.7|89/92|BATS| HM:PFM:REP 61->218|PF04055|1.2e-18|25.7|152/166|Radical_SAM| GO:PFM:NREP 2 GO:PFM GO:0051186|"GO:cofactor metabolic process"|PF06968|IPR010722| GO:PFM GO:0051536|"GO:iron-sulfur cluster binding"|PF06968|IPR010722| RP:SCP:NREP 1 RP:SCP:REP 41->325|1r30A|1e-65|33.5|281/314|c.1.28.1| HM:SCP:REP 13->325|1r30A_|2.3e-76|41.7|307/312|c.1.28.1|1/1|Radical SAM enzymes| OP:NHOMO 818 OP:NHOMOORG 790 OP:PATTERN ------------------------1--1---1---11111111-----------------------11 ----212111111111111-111111111111111121111121---1----111111--1111111111-------------11111111--111----1111111121-------1-11111-111111111-1----------11111111-1111111111111111111111111111---11---111111111111111111-111111111111---------111111111111111111111---------------------------1111----------------------------------------11-111111111111-111111--11---1111--111---1----1-111111111-----111111111111111111111111-11111111-3111111--1-----11111--21-11--111111111111111--1111111111--------1-----------11111111111111112111111111111111111111-11111111111211-11111111-1121111111111-1-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--111111-11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--------------------------------------------111-1 ------------1111111111111-11111-111111111111111111111111-11111111-11---1111111111111-111-12111111111111111-11----------------------------------------------------------------1-111181111121231111121122 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 288 STR:RPRED 87.5 SQ:SECSTR #######################################ccccTTccHHHHHHHHHHHHccccccHHHHHHHccHHHHHHHHHHHHHHHcccHHHHHHHHccHHHHHHHHHHHccTTTHHHHHHHHHHccccccTHHHHHHHHHHccHHHHHHHHHHHHHHHcccHHccHHHHHHHHHHHTccccccccccHHHHHHHHHHHHHHHHTTTcHHHHHHHHHHccHHHHHHHHHHHHHHHcccGGGTTcGcccccccHHHHHHHHHHHHHHcHHHHHHHHHHHHHccccccHHHHHHHccccccccccHHHHHHHHHHHHTTcccccHH## DISOP:02AL 329-330| PSIPRED ccHHHHHHHHHccccccHHHHHHHHHccHHHHHHHHHHHHHHHHHHcccEEEEEEEEEEEccccccccccccccccccccccccccccHHHHHHHHHHHHHccccEEEEEcccccccHHHHHHHHHHHHHHHHHcccEEEEEcccccHHHHHHHHHccccEEEEEHHHHHHHHHHHcccccHHHHHHHHHHHHHccccEEEEEEEcccccHHHHHHHHHHHHHccccEEEEEEEEcccccccccccccccccHHHHHHHHHHHHHHccccccEEEccHHHHccHHHHHHHHHccEEEEccccccccccHHHHHHHHHHcccccHHcccc //