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Thermus thermophilus HB27 (tthe0)
Gene : AAS80595.1
DDBJ      :             carbamoyl-phosphate synthase large chain
Swiss-Prot:CARB_THET2   RecName: Full=Carbamoyl-phosphate synthase large chain;         EC=6.3.5.5;AltName: Full=Carbamoyl-phosphate synthetase ammonia chain;

Homologs  Archaea  56/68 : Bacteria  827/915 : Eukaryota  190/199 : Viruses  0/175   --->[See Alignment]
a.92.1c.24.1c.30.1d.142.1f.6.1
:1028 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->995 1bxrA PDBj 0.0 57.0 %
:RPS:PDB   1->1024 1ce8A PDBj 0.0 53.6 %
:RPS:SCOP  1->127 1a9xA3  c.30.1.1 * 4e-19 63.0 %
:RPS:SCOP  128->408 1a9xA5  d.142.1.2 * 1e-66 67.9 %
:RPS:SCOP  495->700 1lkfA  f.6.1.1 * 7e-52 12.7 %
:RPS:SCOP  673->932 1a9xA6  d.142.1.2 * 1e-54 52.7 %
:RPS:SCOP  981->1021 1b93A  c.24.1.2 * 1e-04 17.1 %
:HMM:SCOP  4->130 1a9xA4 c.30.1.1 * 2e-48 60.3 %
:HMM:SCOP  128->408 1a9xA5 d.142.1.2 * 4.2e-106 54.4 %
:HMM:SCOP  402->551 1a9xA1 a.92.1.1 * 4.6e-53 54.0 %
:HMM:SCOP  551->671 1a9xA4 c.30.1.1 * 1.9e-54 69.4 %
:HMM:SCOP  669->932 1a9xA5 d.142.1.2 * 5.4e-93 55.1 %
:RPS:PFM   6->123 PF00289 * CPSase_L_chain 5e-20 45.8 %
:RPS:PFM   128->333 PF02786 * CPSase_L_D2 7e-32 42.6 %
:RPS:PFM   421->543 PF02787 * CPSase_L_D3 7e-30 55.0 %
:RPS:PFM   556->664 PF00289 * CPSase_L_chain 2e-23 62.1 %
:RPS:PFM   669->870 PF02786 * CPSase_L_D2 3e-27 38.8 %
:HMM:PFM   128->334 PF02786 * CPSase_L_D2 6.8e-70 41.7 204/211  
:HMM:PFM   669->872 PF02786 * CPSase_L_D2 2.5e-34 28.7 202/211  
:HMM:PFM   7->123 PF00289 * CPSase_L_chain 1.3e-22 38.6 101/110  
:HMM:PFM   555->664 PF00289 * CPSase_L_chain 9.1e-27 45.8 96/110  
:HMM:PFM   428->543 PF02787 * CPSase_L_D3 7.7e-44 57.4 115/121  
:BLT:SWISS 1->1028 CARB_THET2 0.0 100.0 %
:PROS 164->178|PS00866|CPSASE_1
:PROS 705->719|PS00866|CPSASE_1
:PROS 297->304|PS00867|CPSASE_2
:PROS 835->842|PS00867|CPSASE_2
:REPEAT 2|9->485|556->1021

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS80595.1 GT:GENE AAS80595.1 GT:PRODUCT carbamoyl-phosphate synthase large chain GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION complement(233223..236309) GB:FROM 233223 GB:TO 236309 GB:DIRECTION - GB:PRODUCT carbamoyl-phosphate synthase large chain GB:PROTEIN_ID AAS80595.1 GB:DB_XREF GI:46196177 LENGTH 1028 SQ:AASEQ MPPRRDLKKILIIGSGPITIGQAAEFDYSGTQAVKALRGAGYRVVLVNSNPATIMTDPELAERTYIEPLDLEHLEGILAREAPDALLPTLGGQTGLNLAMALYEEGILQKYGVELIGAKAEAIRKGEDREAFQEAMRRIDLEVPRGQLVGSVEEGLHFAREVGFPVVVRPSFTLGGTGGGIAHDEAELVEVLSRGLTLSPVHTALVEESVLGWKEFELEVMRDHADTVVIITSIENVDPMGVHTGDSITVAPAQTLSDVEYQRMRDAAKAIIREIGVETGGSNIQFAVDPKTGRQVVIEMNPRVSRSSALASKATGFPIAKIAALLAVGYRLDELPNDITRKTPASFEPTIDYVVVKIPRFAFEKFRPLRNTLGELKDELTTQMKSVGEVMAIGRTFKEALMKALRGLERDVRALAGVRTEELEKKLYPNPDRVYAVMELLRRGMPVEELYQATRIDPWFLHQMKEIVEAEEWLKTHPPKDREDWRFYKGLGLTDRRIGELLGKGEKEVRAERKALGVVPVYKTVDTCAAEFEAYTPYHYSTYELEDEVWPSQKPKVVILGSGPIRIGQGVEFDYATVHAVWALKEAGFETIMVNSNPETVSTDYDTADRLYFEPLTLEDVLNIVEHEKPIGVIATLGGQTPLKLAKGLEEAGVRLLGTPFSAIHQAEDREAFHALCQRLGIPQPEGRVAQSPEEALRLAPEVGFPLLVRPSYVLGGRAMQVVRDEGELKRYLEEVYAPLEERPSILLDRFLEGAIELDVDALSDGQEVMVAGIMEHVERAGVHSGDSATLLPPVHVPEEALKKVRDYTRRLALTLGVRGLLNVQYAVVGEEVYVLEANPRASRTVPFVSKAIGVPLAKLAALIAVGKTLKELGVRDLDPVPPYYAAKEVVIPWIKFPGVIPELGPEMRSTGESMGIDQDPYLAYYKAELGAGQRLPLSGQVRFIGEGLEDLKALYQEAGFALTEGQDYDLLISLVPDPELRRAVERGLPFITTREGAWWSLKAILRARESGLRVQSLQDWHQKAPRG GT:EXON 1|1-1028:0| SW:ID CARB_THET2 SW:DE RecName: Full=Carbamoyl-phosphate synthase large chain; EC=6.3.5.5;AltName: Full=Carbamoyl-phosphate synthetase ammonia chain; SW:GN Name=carB; OrderedLocusNames=TT_C0247; SW:KW Amino-acid biosynthesis; Arginine biosynthesis; ATP-binding;Complete proteome; Ligase; Magnesium; Manganese; Metal-binding;Nucleotide-binding; Pyrimidine biosynthesis; Repeat. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1028|CARB_THET2|0.0|100.0|1028/1028| GO:SWS:NREP 7 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0006526|"GO:arginine biosynthetic process"|Arginine biosynthesis| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006221|"GO:pyrimidine nucleotide biosynthetic process"|Pyrimidine biosynthesis| PROS 164->178|PS00866|CPSASE_1|PDOC00676| PROS 705->719|PS00866|CPSASE_1|PDOC00676| PROS 297->304|PS00867|CPSASE_2|PDOC00676| PROS 835->842|PS00867|CPSASE_2|PDOC00676| NREPEAT 1 REPEAT 2|9->485|556->1021| BL:PDB:NREP 1 BL:PDB:REP 1->995|1bxrA|0.0|57.0|982/1073| RP:PDB:NREP 1 RP:PDB:REP 1->1024|1ce8A|0.0|53.6|998/1058| RP:PFM:NREP 5 RP:PFM:REP 6->123|PF00289|5e-20|45.8|102/102|CPSase_L_chain| RP:PFM:REP 128->333|PF02786|7e-32|42.6|202/207|CPSase_L_D2| RP:PFM:REP 421->543|PF02787|7e-30|55.0|120/123|CPSase_L_D3| RP:PFM:REP 556->664|PF00289|2e-23|62.1|95/102|CPSase_L_chain| RP:PFM:REP 669->870|PF02786|3e-27|38.8|200/207|CPSase_L_D2| HM:PFM:NREP 5 HM:PFM:REP 128->334|PF02786|6.8e-70|41.7|204/211|CPSase_L_D2| HM:PFM:REP 669->872|PF02786|2.5e-34|28.7|202/211|CPSase_L_D2| HM:PFM:REP 7->123|PF00289|1.3e-22|38.6|101/110|CPSase_L_chain| HM:PFM:REP 555->664|PF00289|9.1e-27|45.8|96/110|CPSase_L_chain| HM:PFM:REP 428->543|PF02787|7.7e-44|57.4|115/121|CPSase_L_D3| GO:PFM:NREP 12 GO:PFM GO:0003824|"GO:catalytic activity"|PF00289|IPR005481| GO:PFM GO:0008152|"GO:metabolic process"|PF00289|IPR005481| GO:PFM GO:0003824|"GO:catalytic activity"|PF02786|IPR005479| GO:PFM GO:0005524|"GO:ATP binding"|PF02786|IPR005479| GO:PFM GO:0008152|"GO:metabolic process"|PF02786|IPR005479| GO:PFM GO:0004086|"GO:carbamoyl-phosphate synthase activity"|PF02787|IPR005480| GO:PFM GO:0006807|"GO:nitrogen compound metabolic process"|PF02787|IPR005480| GO:PFM GO:0003824|"GO:catalytic activity"|PF00289|IPR005481| GO:PFM GO:0008152|"GO:metabolic process"|PF00289|IPR005481| GO:PFM GO:0003824|"GO:catalytic activity"|PF02786|IPR005479| GO:PFM GO:0005524|"GO:ATP binding"|PF02786|IPR005479| GO:PFM GO:0008152|"GO:metabolic process"|PF02786|IPR005479| RP:SCP:NREP 5 RP:SCP:REP 1->127|1a9xA3|4e-19|63.0|127/127|c.30.1.1| RP:SCP:REP 128->408|1a9xA5|1e-66|67.9|274/275|d.142.1.2| RP:SCP:REP 495->700|1lkfA|7e-52|12.7|173/292|f.6.1.1| RP:SCP:REP 673->932|1a9xA6|1e-54|52.7|243/244|d.142.1.2| RP:SCP:REP 981->1021|1b93A|1e-04|17.1|41/148|c.24.1.2| HM:SCP:REP 4->130|1a9xA4|2e-48|60.3|121/0|c.30.1.1|1/2|PreATP-grasp domain| HM:SCP:REP 128->408|1a9xA5|4.2e-106|54.4|274/0|d.142.1.2|1/2|Glutathione synthetase ATP-binding domain-like| HM:SCP:REP 402->551|1a9xA1|4.6e-53|54.0|150/153|a.92.1.1|1/1|Carbamoyl phosphate synthetase, large subunit connection domain| HM:SCP:REP 551->671|1a9xA4|1.9e-54|69.4|121/0|c.30.1.1|2/2|PreATP-grasp domain| HM:SCP:REP 669->932|1a9xA5|5.4e-93|55.1|263/0|d.142.1.2|2/2|Glutathione synthetase ATP-binding domain-like| OP:NHOMO 1765 OP:NHOMOORG 1073 OP:PATTERN ---1-2221111111111111111111111112242241111211211131223-1-----111--21 2121221122211321122-2211112222212111243213221121112222311111221221111121111222112115334422241211-1111112111111---------------22222223222111222221111111111111111112111111112111211121111111122113322222222322222234443322254513332111113112222222222222222222121111232323222111132211112221111111111111111111111111111111111111111122-211112221111243322122-2--2112333132211211112-12121111122222211111112212222222222222-11211121211213321141112311122222212222111111111111112121112211111---------------1111111111243311111111111122111111111111111112212222221131111111111112111111113113212111111211111211211123323112231111111111111111111212211111123111111211111111111111111111-111111111121211111111111111-11111111111111111121111111111111111111111111111111111111111111111111111111333311322---1-11----1--111111111112122221333322233223122221222212211111111111111111111111111111111111--------1-1---------------------------1--11111132 12--223-311-11222334332222322223222222223222223322232232332222232223222332232-3223333322-2322324222222-444-22273322332222222432416J2-3221222212211321222122222237513211211A31613111K2211131442122353223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1024 STR:RPRED 99.6 SQ:SECSTR ccccccccEEEEEccccccTTccTHHHHHHHHHHHHHHHTTcEEEEEccccccGGGcGGGccEEEcccccHHHHHHHHHHHcccEEEccccHHHHHHHHHHHHHTTHHHHHTcEEccccHHHHHHHHcHHHHHHHHHHTTcccccEEEEccHHHHHHHHHHHcccEEEEETTccTTTTcEEEccHHHHHHHHHHHHHHcTTccEEEEEccTTcEEEEEEEEEcTTccEEEEEEEEEcccTTccTTcccEEEccccccHHHHHHHHHHHHHHHHHHTcccEEEEEEEEEETTTTEEEEEEEEccccHHHHHHHHHHcccHHHHHHHHHTTccGGGcccGGGTccccccccccccEEEEEEEccGGGcTEEcccccTccccccccccccEEEEEEEccHHHHHHHHHHHccccccTTcTTHHHHHHHHHcccTTHHHHHHHHHHTTccHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHTGGcHHHHHHHHHTTccHHHHHHHTTccHHHHHHHHHHTTcccEEEEccccTTcccccccEEEEEccccccccccccccEEEEccccccTTccHHHHHHHHHHHHHHHHTTcEEEEEcccTTccTTcGGGccEEEcccccHHHHHHHHHHHcccEEEccccTHHHHHHHHHHHHTTcccccccHHHHHHHHcHHHHHHHHHHHTcccccEEEcccHHHHHHHHHHHcccEEEEcccEEEccHHHHHHHHHHccEEEcHHHHHcTHHHccEEEEccTTcEEEEEEEEEccccEEEEEEEEEEEETTccGGGccEEEccccccHHHHHHHHHHHHHHHHHHTccEEEEEEEEEccccEEEEEEEccccTTHHHHHHHHTccHHHHHHHHHTTccHHHHTcccTccccccEEEEEEEcGGGGcTTccccccccccccEEEEEEEccHHHHHHHHHHHTTcccccccEEEEcHHHHHHHHTTTcccEEcGccccHHHHHHHHHHHHHHHHHHHTTcEEEccHHHHHHHHHHTTccTTTcccEEcHHHHHHT#### DISOP:02AL 1-4, 1023-1028| PSIPRED ccccccccEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEccccHHHcccHHHccEEEEEEccHHHHHHHHHHHcccEEEEEcccccccHHHHHHHHHHHHHHcccEEEcccHHHHHHHccHHHHHHHHHHcccccccccccccHHHHHHHHHHccccEEEEccccccccccEEEEcHHHHHHHHHHHHHHcccccEEEEEEcccccEEEEEEEEEccccEEEEEccccccccccccccEEEEEccccccHHHHHHHHHHHHHHHHHcccEEccEEEEEEEEcccccEEEEEEEccccccHHHHHHHHcccHHHHHHHHHccccccccccccccccccEEEEcccccccccccccccccccccccccccccccccccccEEEEEEEcccHHHHHHHHHHHHcccccccccccHHHHHHHHccccHHHHHHHHHHHccccHHHHHHHHcccHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHccccHHHHHHHHcccHHHHHHHHHHcccEEEEEEEcccccccccccccEEEEEcccccccccccccEEEEccccEEEccHHHHHHHHHHHHHHHHHcccEEEEEEccccccccHHHHccEEEEEcccHHHHHHHHHHHcccEEEEccccccHHHHHHHHHHcccccccccHHHHHHHHcHHHHHHHHHHcccccccccccccHHHHHHHHHHccccEEEEEccccccccEEEEccHHHHHHHHHHHHHHccccccEEEEEEccccEEEEEEEEEEccEEEEEEEEcccccccccccccEEEEccccccHHHHHHHHHHHHHHHHHcccEEEEEEEEEEEcccEEEEEEEcccccHHHHHHHHHcccHHHHHHHHHccccccccccccccccccEEEEccccccccccccccccccccEEEccEEEEEEccHHHHHHHHHHHcccccccccEEEEEEEcHHHHHHHHHHcccEEEEccHHHHHHHcccHHHHHHHHHccccEEEcHHHHHHHHHHHHHHcccccEEEEHHHHHHccccc //