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Thermus thermophilus HB27 (tthe0)
Gene : AAS81065.1
DDBJ      :             UDP-N-acetylmuramoylalanine-D-glutamate ligase
Swiss-Prot:MURD_THET8   RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase;         EC=6.3.2.9;AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase;AltName: Full=D-glutamic acid-adding enzyme;

Homologs  Archaea  0/68 : Bacteria  654/915 : Eukaryota  6/199 : Viruses  0/175   --->[See Alignment]
c.5.1c.59.1c.72.2
:417 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->408 1eehA PDBj 8e-21 31.9 %
:RPS:PDB   40->407 1e8cB PDBj 3e-27 13.9 %
:RPS:SCOP  4->83 1e0dA1  c.5.1.1 * 2e-07 30.0 %
:RPS:SCOP  84->232 1e0dA3  c.72.2.1 * 2e-21 25.7 %
:RPS:SCOP  267->408 1e0dA2  c.59.1.1 * 7e-18 26.1 %
:HMM:SCOP  3->83 2uagA1 c.5.1.1 * 1.4e-10 37.5 %
:HMM:SCOP  84->263 2uagA3 c.72.2.1 * 9.2e-39 40.9 %
:HMM:SCOP  265->408 2uagA2 c.59.1.1 * 1.7e-30 41.9 %
:RPS:PFM   99->222 PF08245 * Mur_ligase_M 7e-12 39.5 %
:HMM:PFM   99->226 PF08245 * Mur_ligase_M 7.4e-36 43.7 126/188  
:HMM:PFM   267->331 PF02875 * Mur_ligase_C 1.7e-09 29.7 64/91  
:BLT:SWISS 1->417 MURD_THET8 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS81065.1 GT:GENE AAS81065.1 GT:PRODUCT UDP-N-acetylmuramoylalanine-D-glutamate ligase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION 701794..703047 GB:FROM 701794 GB:TO 703047 GB:DIRECTION + GB:PRODUCT UDP-N-acetylmuramoylalanine-D-glutamate ligase GB:PROTEIN_ID AAS81065.1 GB:DB_XREF GI:46196649 LENGTH 417 SQ:AASEQ MRLVYGLGRSGLGVLRFLRKRGLPARFYDDRPREEEVREALALGFQPDWNLEEAYEEVVAAPGVPLDHPHLKRLAARGAKVLGEAELAYRLSPTPIVGITGTAGKTSTTLFTAHLLRAHGLRAREGGNVDPPLVSVVDEAEVAVAELSSFQLERVHAFRPRVAVLLNLGVDHLDRHGTVEAYHAAKLNLLKNLTPEDALVYNRLDPKVRRAAEASPARLYPFTPGSTPRETNLRAALEATRAYLDLLGRPLDPGAVAEALRTLPEAPHRFQAFARKGGVVFIDDSIATRTEAVRAALEAAPAPIAWILGGEDKGADLAPLLPLLGRVRVALALGRDGPRFARALEGRTEVVVIAEKDGRTAMRKAVEEALSRLEQGSVLLAPLAASFDQFRDYKDRAQAFREAVFALGGEPWTPSSS GT:EXON 1|1-417:0| SW:ID MURD_THET8 SW:DE RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; EC=6.3.2.9;AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase;AltName: Full=D-glutamic acid-adding enzyme; SW:GN Name=murD; OrderedLocusNames=TTHA1082; SW:KW ATP-binding; Cell cycle; Cell division; Cell shape;Cell wall biogenesis/degradation; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Peptidoglycan synthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->417|MURD_THET8|0.0|100.0|417/417| GO:SWS:NREP 9 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0007049|"GO:cell cycle"|Cell cycle| GO:SWS GO:0051301|"GO:cell division"|Cell division| GO:SWS GO:0008360|"GO:regulation of cell shape"|Cell shape| GO:SWS GO:0007047|"GO:cellular cell wall organization"|Cell wall biogenesis/degradation| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0009252|"GO:peptidoglycan biosynthetic process"|Peptidoglycan synthesis| SEG 133->149|lvsvvdeaevavaelss| SEG 287->308|atrteavraaleaapapiawil| SEG 317->335|lapllpllgrvrvalalgr| BL:PDB:NREP 1 BL:PDB:REP 3->408|1eehA|8e-21|31.9|386/431| RP:PDB:NREP 1 RP:PDB:REP 40->407|1e8cB|3e-27|13.9|360/484| RP:PFM:NREP 1 RP:PFM:REP 99->222|PF08245|7e-12|39.5|124/187|Mur_ligase_M| HM:PFM:NREP 2 HM:PFM:REP 99->226|PF08245|7.4e-36|43.7|126/188|Mur_ligase_M| HM:PFM:REP 267->331|PF02875|1.7e-09|29.7|64/91|Mur_ligase_C| GO:PFM:NREP 2 GO:PFM GO:0005524|"GO:ATP binding"|PF08245|IPR013221| GO:PFM GO:0009058|"GO:biosynthetic process"|PF08245|IPR013221| RP:SCP:NREP 3 RP:SCP:REP 4->83|1e0dA1|2e-07|30.0|80/93|c.5.1.1| RP:SCP:REP 84->232|1e0dA3|2e-21|25.7|140/196|c.72.2.1| RP:SCP:REP 267->408|1e0dA2|7e-18|26.1|134/140|c.59.1.1| HM:SCP:REP 3->83|2uagA1|1.4e-10|37.5|80/93|c.5.1.1|1/1|MurCD N-terminal domain| HM:SCP:REP 84->263|2uagA3|9.2e-39|40.9|176/204|c.72.2.1|1/1|MurD-like peptide ligases, catalytic domain| HM:SCP:REP 265->408|2uagA2|1.7e-30|41.9|136/140|c.59.1.1|1/1|MurD-like peptide ligases, peptide-binding domain| OP:NHOMO 666 OP:NHOMOORG 660 OP:PATTERN -------------------------------------------------------------------- 1111--------1-------------------------------1-111--1-1-11-11--1-1--11111111111----21111-111111111--111111111-1-------111----1-1-11-2-11-----------1--111111--111111-1-1---11111111111111111111-111111111111111111111111111111211111111111111111111111111111111111--1111111----1-11-1111111111111111111111111111111111111111111111111111-1111111-1-111111111111-1-1111111111111111-11111-111111111111111111111111111111111-11111111111111111111111111111111111111------------1--1111--------11111111111111111111111111111------------------------------------1111-1111111-111--1111111111---11111111111111111111111111111111-----11111----------11-1111111111-11-11----111111111111111-1111111-111111-1111111111111-11111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111---1111111111111111111111111111111111111111-1111------------111-1111--------------------------------------1---11-111111 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------11----------2--1--2--1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 406 STR:RPRED 97.4 SQ:SECSTR ##EEEcccccHHHHHHHHTcccccTTccccccccGGccTTTTccTTcEcEETTEEEEEETTHHHHHHHHHHTTcGGGccEEEEEEccccHHHHHHHHHHHHHTTccEEEcTTccEETTcccccccccccHHHHHHHHHHHHHTTccEEEHHHTTTTTccccEEEEcccccccHHHHccHHHHHHHHHHHcccTTcccEEEEETTcHHHHHHHTTcTTcEcTTTccEEEEEEEEEEccccEEEEEEETTccHcHHHHHHHGGGccccTTcEEEccTTccEEEEEccHHHHHHHHHHHHTccccEEEEEccccccccTHHHHHHHHHHHccEEEEccccccTccHHHHHHHHHTTccTTccEEHHHHHHHHHHccTTcEEEEEccccTTccEEEETTEEEEccHHHHHHc######### DISOP:02AL 412-417| PSIPRED cEEEEEEcHHHHHHHHHHHHcccEEEEEEccccHHHHHHHHHHccccHHHccccccEEEEcccccccccHHHHHHHcccccccHHHHHHHHccccEEEEEcccccHHHHHHHHHHHHHccccEEEEccccHHHHHHcccccEEEEEcccccHHHHHcccccEEEEEcccHHHHHHcccHHHHHHHHHHHHHccccccEEEEEcccHHHHHHHHHccccEEEEccccccHHHcHHHHHHHHHHHHHHHcccccHHHHHHHHHHcccccccEEEEEccccEEEEEccccccHHHHHHHHHHccccEEEEEEcccccHHHHHHHHHHHHccEEEEEcccHHHHHHHHHHHccEEEEccHHHHHHHHHHHHHHHHHccccEEEEEcccccHHHHHHHHHHHHHHHHHHHHccccccccccc //