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Thermus thermophilus HB27 (tthe0)
Gene : AAS81194.1
DDBJ      :             ketol-acid reductoisomerase
Swiss-Prot:ILVC_THET8   RecName: Full=Ketol-acid reductoisomerase;         EC=1.1.1.86;AltName: Full=Acetohydroxy-acid isomeroreductase;AltName: Full=Alpha-keto-beta-hydroxylacil reductoisomerase;

Homologs  Archaea  52/68 : Bacteria  734/915 : Eukaryota  112/199 : Viruses  0/175   --->[See Alignment]
a.100.1c.127.1c.2.1d.58.56
:337 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   1->328 1np3A PDBj e-106 56.0 %
:RPS:PDB   1->44 2dwcB PDBj 2e-04 22.7 %
:RPS:PDB   53->278 2b0jA PDBj 5e-29 20.0 %
:RPS:SCOP  2->100 2a10A1  d.58.56.1 * 1e-21 19.8 %
:RPS:SCOP  72->282 1qv9A  c.127.1.1 * 2e-52 17.7 %
:HMM:SCOP  1->182 1np3A2 c.2.1.6 * 1.5e-76 67.6 %
:HMM:SCOP  183->333 1qmgA1 a.100.1.2 * 1e-65 61.1 %
:RPS:PFM   16->160 PF07991 * IlvN 2e-62 75.9 %
:RPS:PFM   183->327 PF01450 * IlvC 3e-44 61.5 %
:HMM:PFM   14->177 PF07991 * IlvN 1.8e-81 70.1 164/165  
:HMM:PFM   183->328 PF01450 * IlvC 4.1e-58 56.2 144/145  
:BLT:SWISS 1->337 ILVC_THET8 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS81194.1 GT:GENE AAS81194.1 GT:PRODUCT ketol-acid reductoisomerase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION complement(826928..827941) GB:FROM 826928 GB:TO 827941 GB:DIRECTION - GB:PRODUCT ketol-acid reductoisomerase GB:PROTEIN_ID AAS81194.1 GB:DB_XREF GI:46196779 LENGTH 337 SQ:AASEQ MKIYYEHDADLGFILGKKVAVLGFGSQGHAHALNLKDSGVDVRVGLRKGSRSWEKAEAAGLRVLPVAEAVREADVVMVLLPDEKQAQVYREEVEPNLKEGGALAFAHGFNVHFGQIKPRKDLDVWMVAPKGPGHLVRSEYQKGSGVPALVAVHQDASGSAFPTALAYAKAIGAARAGVIATTFKDETETDLFGEQAVLCGGLTRLIRAGFETLVEAGYPPEMAYFETVHEVKLIVDLIYEAGLKGMRYSISNTAEYGDYTRGDLAVPLEETKRRMREILRQIQSGEFAREWMLENQVGSPVLEANRKRWAAHPIEEVGSRLRAMMPFLKARVMEEVG GT:EXON 1|1-337:0| SW:ID ILVC_THET8 SW:DE RecName: Full=Ketol-acid reductoisomerase; EC=1.1.1.86;AltName: Full=Acetohydroxy-acid isomeroreductase;AltName: Full=Alpha-keto-beta-hydroxylacil reductoisomerase; SW:GN Name=ilvC; OrderedLocusNames=TTHA1211; SW:KW Amino-acid biosynthesis; Branched-chain amino acid biosynthesis;Complete proteome; NADP; Oxidoreductase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->337|ILVC_THET8|0.0|100.0|337/337| GO:SWS:NREP 4 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009082|"GO:branched chain family amino acid biosynthetic process"|Branched-chain amino acid biosynthesis| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| SEG 164->180|alayakaigaaragvia| BL:PDB:NREP 1 BL:PDB:REP 1->328|1np3A|e-106|56.0|327/327| RP:PDB:NREP 2 RP:PDB:REP 1->44|2dwcB|2e-04|22.7|44/409| RP:PDB:REP 53->278|2b0jA|5e-29|20.0|210/344| RP:PFM:NREP 2 RP:PFM:REP 16->160|PF07991|2e-62|75.9|145/165|IlvN| RP:PFM:REP 183->327|PF01450|3e-44|61.5|143/145|IlvC| HM:PFM:NREP 2 HM:PFM:REP 14->177|PF07991|1.8e-81|70.1|164/165|IlvN| HM:PFM:REP 183->328|PF01450|4.1e-58|56.2|144/145|IlvC| GO:PFM:NREP 6 GO:PFM GO:0004455|"GO:ketol-acid reductoisomerase activity"|PF07991|IPR013116| GO:PFM GO:0008652|"GO:cellular amino acid biosynthetic process"|PF07991|IPR013116| GO:PFM GO:0055114|"GO:oxidation reduction"|PF07991|IPR013116| GO:PFM GO:0004455|"GO:ketol-acid reductoisomerase activity"|PF01450|IPR000506| GO:PFM GO:0009082|"GO:branched chain family amino acid biosynthetic process"|PF01450|IPR000506| GO:PFM GO:0055114|"GO:oxidation reduction"|PF01450|IPR000506| RP:SCP:NREP 2 RP:SCP:REP 2->100|2a10A1|1e-21|19.8|86/104|d.58.56.1| RP:SCP:REP 72->282|1qv9A|2e-52|17.7|186/282|c.127.1.1| HM:SCP:REP 1->182|1np3A2|1.5e-76|67.6|182/0|c.2.1.6|1/1|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 183->333|1qmgA1|1e-65|61.1|149/288|a.100.1.2|1/1|6-phosphogluconate dehydrogenase C-terminal domain-like| OP:NHOMO 969 OP:NHOMOORG 898 OP:PATTERN ---1--1122222231-11111111--11111111111111111121111111111-----1--1-11 1111111111111111111-1111111111111111111111111111111111111111112111112112111222-11-111111111111---11--111111111---------------11111111111111111111111111111111111111111111111111111111111111111-11122222222122222211111122211111--1111111111111111111111111111---------------------1-111-------11111111111111-------------111111111-11-11-------1-111221---1-1--111111111111-111111--1-11111111111111111111111111111111111-11111111111-111111111111111121111111111111111111111111111---------------------------11111111111111111122211111222212111111111111111111111111111111111111111111111-1111111111111-1111111111111-1121111111111111111111111111111111111-1111111111111111111111-1-111111111111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111-----------11111111111-11111111111111111111111111111111111111-1-1111-111111111111111111111111111111111111111--------------------------------------1--1-111121 --------------1111111111111-111111111111111-1111111111111-1111111111-11111111-1111111111-24211211111111212--1----------------------------------------------------------------1-1111B1111122231111111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 336 STR:RPRED 99.7 SQ:SECSTR THHHHHHHHHHcccTTcEEEEEcTcHHHHHHHHcGGGGcTTcccccccccHHcccGGGGTcEEEccHHHHTTccEEEEccTTcTTHHHHHHHHGGGccTTcEEEEccccHHHHHHHHHHTTcTTcEEEEcccccHTTHHHHHHHTcTTTcccEEEEEccccHHHHHHHHHHHHHHEEEccHccEEEEEHHHHHHHHcTTHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHcGGGHHHHccGGGGGGTGGGGccGGGTTHHHHHHHHHHHHHHHcTTccEEEEEEccccTTcccccccHHHHHHHHHHHHHcccccEccccccHHH# PSIPRED cEEEEEcccccccccccEEEEEcccccHHHHHHHHHHcccEEEEEEEcccccHHHHHHcccEEccHHHHHHcccEEEEEccHHHHHHHccHHHHHHcccccEEEEccccEEEEcEEEcccccEEEEEccccccHHHHHHHHHccccEEEEEEEEcccccHHHHHHHHHHHcccccHHHHHccHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHccccHHHHHcccHHHHHHHHHHHHHHHcccHHHHHHHHHHHcccHHHHHHHHHHHccHHHHHHHHHHHHHHHHcHHHHHHcc //