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Thermus thermophilus HB27 (tthe0)
Gene : AAS81324.1
DDBJ      :             endonuclease V
Swiss-Prot:NFI_THET8    RecName: Full=Endonuclease V;         EC=3.1.21.7;AltName: Full=Deoxyinosine 3'endonuclease;AltName: Full=Deoxyribonuclease V;         Short=DNase V;

Homologs  Archaea  45/68 : Bacteria  181/915 : Eukaryota  62/199 : Viruses  0/175   --->[See Alignment]
:226 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   13->223 2w35A PDBj 9e-30 37.6 %
:RPS:PDB   113->161 3c65A PDBj 7e-05 20.4 %
:RPS:PFM   35->216 PF04493 * Endonuclease_5 7e-23 42.5 %
:HMM:PFM   19->217 PF04493 * Endonuclease_5 1.4e-51 41.1 197/206  
:BLT:SWISS 13->226 NFI_THET8 e-106 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS81324.1 GT:GENE AAS81324.1 GT:PRODUCT endonuclease V GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION 965652..966332 GB:FROM 965652 GB:TO 966332 GB:DIRECTION + GB:PRODUCT endonuclease V GB:PROTEIN_ID AAS81324.1 GB:DB_XREF GI:46196909 LENGTH 226 SQ:AASEQ MRPPPFPKPAHPEEALALQRALAKKVRLAGSLEGVRRIAALDASHKRGRPLVAVALLYDLEKGPLHVATALLPEEALFPYVPGLLSFREAPAYLEALAALPEAPEALLVDGQGVAHPRGLGIASHLGVHLDLPSVGVAKRLLYGRPEAPLPEEKGAAVRLLAPDGRPLGYVYRSRTGVKPLYVSPGHRVGLEEALRFVRRLPTRFRLPEPLRLAHLEAGRALKALD GT:EXON 1|1-226:0| SW:ID NFI_THET8 SW:DE RecName: Full=Endonuclease V; EC=3.1.21.7;AltName: Full=Deoxyinosine 3'endonuclease;AltName: Full=Deoxyribonuclease V; Short=DNase V; SW:GN Name=nfi; OrderedLocusNames=TTHA1347; SW:KW Complete proteome; Cytoplasm; DNA damage; DNA repair; Endonuclease;Hydrolase; Magnesium; Nuclease. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 13->226|NFI_THET8|e-106|100.0|214/226| GO:SWS:NREP 6 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0004519|"GO:endonuclease activity"|Endonuclease| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0004518|"GO:nuclease activity"|Nuclease| SEG 3->12|pppfpkpahp| SEG 89->108|eapaylealaalpeapeall| BL:PDB:NREP 1 BL:PDB:REP 13->223|2w35A|9e-30|37.6|205/223| RP:PDB:NREP 1 RP:PDB:REP 113->161|3c65A|7e-05|20.4|49/149| RP:PFM:NREP 1 RP:PFM:REP 35->216|PF04493|7e-23|42.5|181/195|Endonuclease_5| HM:PFM:NREP 1 HM:PFM:REP 19->217|PF04493|1.4e-51|41.1|197/206|Endonuclease_5| GO:PFM:NREP 2 GO:PFM GO:0004519|"GO:endonuclease activity"|PF04493|IPR007581| GO:PFM GO:0006281|"GO:DNA repair"|PF04493|IPR007581| OP:NHOMO 320 OP:NHOMOORG 288 OP:PATTERN 111111111111111-1111111111111111--------------1-1----11-1111111111-- ----1-------------------------------1------1----------------21--1111111-----------111111-----------------2-11---------------1-----------1111111111211111-----------1--1111----------------1111---1--------------------11---------------1----------------------------------------------------------------------------------------------12---------------------------1--------------1---------------------------------------1111111----------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------11-----1-11--------------------------------2---------------------------11-1------11111111111111111-1111111111111111111111-11111111111111111111111111111-111111111111-------------1--1--------------------------1---------1----1---------------------------11111111111111----------------------------------------------1111111111--- ----1-1---1---1-----------------------------------------------------------------------11---------------111-1-221311--1-1-11-32-21291-2231---2-112-1---1--21111-11-1211-------11--1-------1111-21--11111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 211 STR:RPRED 93.4 SQ:SECSTR ############HHHHHHHHHHGGGcccccccccccEEEEEEEEEEETTEEEEEEEEEETETTTTTEEEEEEEEEccccccTTcHHHHHHHHHHHHHTTccccccEEEEccccHHHHHHHHHHHHHTccccccEEEccccEETTTTEEccccTTcHHHHHHEETTEEEEEEEcccTTcccEEEEEcccccHHHHHHHHHccTTcccccHHHHHHHHHHHHHHc### DISOP:02AL 1-3| PSIPRED cccccccccccHHHHHHHHHHHHHHcEEccccccccEEEEEEEEEEccccEEEEEEEEEEccccEEEEEEEEEEEEEccccccHHHHHHHHHHHHHHHHHcccccEEEEcccEEEccccccHHHHHHHHHcccEEEEEcccccccccccccccccccEEEEEcccEEEEEEEEccccccEEEEEccccccHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHcc //