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Thermus thermophilus HB27 (tthe0)
Gene : AAS81502.1
DDBJ      :             serine hydroxymethyltransferase
Swiss-Prot:GLYA_THET2   RecName: Full=Serine hydroxymethyltransferase;         Short=Serine methylase;         Short=SHMT;         EC=2.1.2.1;

Homologs  Archaea  61/68 : Bacteria  896/915 : Eukaryota  191/199 : Viruses  1/175   --->[See Alignment]
c.67.1
:423 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   22->423 2dkjA PDBj 0.0 99.5 %
:RPS:PDB   13->423 1cj0A PDBj 3e-78 50.2 %
:RPS:SCOP  13->423 1bj4A  c.67.1.4 * e-152 49.5 %
:HMM:SCOP  13->423 2a7vA1 c.67.1.4 * 1.3e-179 64.4 %
:RPS:PFM   24->397 PF00464 * SHMT e-160 74.1 %
:HMM:PFM   23->397 PF00464 * SHMT 6.3e-176 63.9 374/399  
:BLT:SWISS 17->423 GLYA_THET2 0.0 100.0 %
:PROS 234->250|PS00096|SHMT

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS81502.1 GT:GENE AAS81502.1 GT:PRODUCT serine hydroxymethyltransferase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION 1126306..1127577 GB:FROM 1126306 GB:TO 1127577 GB:DIRECTION + GB:PRODUCT serine hydroxymethyltransferase GB:PROTEIN_ID AAS81502.1 GB:DB_XREF GI:46197088 LENGTH 423 SQ:AASEQ MRLLPHAAILPGYNRPMVSTLKRDEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEAIDRVESLAIERAKALFGAAWANVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHLTHGSRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFWDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLILSNDPELGKRIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSRLVVENAKRLAEALARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAIPFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRALLEGPSEALREEVRRLALAHPMP GT:EXON 1|1-423:0| SW:ID GLYA_THET2 SW:DE RecName: Full=Serine hydroxymethyltransferase; Short=Serine methylase; Short=SHMT; EC=2.1.2.1; SW:GN Name=glyA; OrderedLocusNames=TT_C1160; SW:KW Complete proteome; Cytoplasm; One-carbon metabolism;Pyridoxal phosphate; Transferase. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 17->423|GLYA_THET2|0.0|100.0|407/407| GO:SWS:NREP 3 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006730|"GO:one-carbon metabolic process"|One-carbon metabolism| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 234->250|PS00096|SHMT|PDOC00090| BL:PDB:NREP 1 BL:PDB:REP 22->423|2dkjA|0.0|99.5|402/402| RP:PDB:NREP 1 RP:PDB:REP 13->423|1cj0A|3e-78|50.2|410/464| RP:PFM:NREP 1 RP:PFM:REP 24->397|PF00464|e-160|74.1|374/378|SHMT| HM:PFM:NREP 1 HM:PFM:REP 23->397|PF00464|6.3e-176|63.9|374/399|SHMT| GO:PFM:NREP 3 GO:PFM GO:0004372|"GO:glycine hydroxymethyltransferase activity"|PF00464|IPR001085| GO:PFM GO:0006544|"GO:glycine metabolic process"|PF00464|IPR001085| GO:PFM GO:0006563|"GO:L-serine metabolic process"|PF00464|IPR001085| RP:SCP:NREP 1 RP:SCP:REP 13->423|1bj4A|e-152|49.5|410/470|c.67.1.4| HM:SCP:REP 13->423|2a7vA1|1.3e-179|64.4|410/0|c.67.1.4|1/1|PLP-dependent transferases|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s3333275DB2943342223 -----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 423 STR:RPRED 100.0 SQ:SECSTR cHHHHHTTcGGGTcccccccHHHcHHHHHHHHHHHHHHHHcEEccTTcccccHHHHHHTTcGGGGcccccccccccccccTTHHHHHHHHHHHHHHHTTccTEEcccccHHHHHHHHHHHHccTTcEEEEEcTTTTccGGGcccccHHHHHcEEEEEcccTTTccccHHHHHHHHHHHcccEEEEccccccccccHHHHHHHHHHHTcEEEEEcTTTHHHHHHTccccGGGTccEEEEEccccccccccEEEEEEcccHHHHHHHHHTTTTcccccHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHTTTcEETTccccccEEEEEGGGGTccHHHHHHHHHHTTEEcEEEccTTccccTTcccEEEEEcHHHHTTTccHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHcccc DISOP:02AL 1-4| PSIPRED ccccccccccHHHHHHHHHHHHccHHHHHHHHHHHHHHHHccEEccccccccHHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHHHHHHHHcccEEEEEcccHHHHHHHHHHHHcccccEEEEccccccccHHHHHHHHHHHHHEEEEEcccccccccccHHHHHHHHHHHccEEEEEccccccccccHHHHHHHHHHcccEEEEEcHHHHHHHcccccccccccccEEEEcccccccccccEEEEcccHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEccccccccEEEEEEccccccHHHHHHHHHHcccEEcccccccccccccccccEEEccHHHHHccccHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHcccc //