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Thermus thermophilus HB27 (tthe0)
Gene : AAS81822.1
DDBJ      :             alanyl-tRNA synthetase
Swiss-Prot:SYA_THET2    RecName: Full=Alanyl-tRNA synthetase;         EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase;         Short=AlaRS;

Homologs  Archaea  53/68 : Bacteria  907/915 : Eukaryota  194/199 : Viruses  0/175   --->[See Alignment]
a.203.1b.43.3d.104.1d.67.1
:882 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->439 1yfrA PDBj e-111 51.7 %
:RPS:PDB   3->444 2cvsA PDBj 2e-57 10.4 %
:RPS:PDB   464->713 2e1bA PDBj 1e-30 19.0 %
:RPS:PDB   690->823 3c9iF PDBj 1e-07 6.1 %
:RPS:SCOP  1->254 1riqA2  d.104.1.1 * 1e-99 55.0 %
:RPS:SCOP  256->471 1riqA1  a.203.1.1 * 6e-58 42.2 %
:RPS:SCOP  464->544 2e1bA1  b.43.3.6 * 1e-11 28.4 %
:RPS:SCOP  585->736 1nyqA3  d.67.1.1 * 2e-23 14.0 %
:HMM:SCOP  1->254 1riqA2 d.104.1.1 * 4.1e-87 59.3 %
:HMM:SCOP  255->474 1riqA1 a.203.1.1 * 4.3e-66 51.2 %
:HMM:SCOP  562->736 1nyrA3 d.67.1.1 * 1.4e-48 46.1 %
:RPS:PFM   5->544 PF01411 * tRNA-synt_2c e-152 52.6 %
:RPS:PFM   678->711 PF07973 * tRNA_SAD 5e-06 63.6 %
:HMM:PFM   5->566 PF01411 * tRNA-synt_2c 2.4e-216 55.3 544/551  
:HMM:PFM   663->712 PF07973 * tRNA_SAD 9.7e-19 61.4 44/44  
:HMM:PFM   840->877 PF02272 * DHHA1 7.9e-07 44.4 36/68  
:BLT:SWISS 1->882 SYA_THET2 0.0 100.0 %
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS81822.1 GT:GENE AAS81822.1 GT:PRODUCT alanyl-tRNA synthetase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION complement(1401661..1404309) GB:FROM 1401661 GB:TO 1404309 GB:DIRECTION - GB:PRODUCT alanyl-tRNA synthetase GB:PROTEIN_ID AAS81822.1 GB:DB_XREF GI:46197409 LENGTH 882 SQ:AASEQ MRTAEIREKFLSFFEGKGHLRLPSFSLIPEDDPSLLFTSAGMAPLKPYFLGAKPIFGGREWRRVTTCQECLRVGDIENVGRTSRHNTYFEMLGNFSFGDYFKKEAILWAWEFLTEHLRLDPGRLWVTVFEDDDEAYEIWRDLVGVPEERIGRFGEDENYWPGGAITHGPNGPSGPCSEIFYDRGPAYGTPDETGPNTGSGDRFVEIWNLVFTQYDRQGPIPGPGILKPLPQKNIDTGMGLYRVAAILQDVEDFYRTDTFFPIIQEVARMSGRPYEGKTSVSHRVIADHVRAVVAALSDGATFSNTGRGYVIRRLLRRALRHGYLLGLSDPFLHRLAPLVAELLGDFYPEMRENLPAVEKQIRLEEERFLETLEGGLKRLDALLSGLKPGEVLPGKEAFRLYDTYGFPLDLTVEIAAERGYGVDTEGFQKAMEEQQSRSRAAMAFEREIFKKGAQVLEELYAERGATEFLGYNALEAEAEVLALLAGDQSLLEAGPGTEVQVVLDKTPFYAEGGGQIGDFGLLEWPGGRARVETTRKTERGIFLHKARVEEGVLRVGERVRAVVDPRRRDTERNHTATHLLHAALRAVLGPHVRQAGSLVAPDRLRFDFTHPEPLKPEELERVELLVNRWIMADFPVTWRYMPLEEARKEGAMALFGEKYGEVVRVVRVEGSPLEGLESKELCGGCHVRRTGEIGAFLIRSEEAVSAGVRRIEAVTGEEAIRFARGSLNRLKALAERLEVGEAALEERLEKLLAELKEKEREVESLKARLVQAALGGGGGASLEEKGGLRWTVAELPGLDAKALRQAADDLVARGADVALVLSGGQAVLKLSPKAQGMGLEAGALFRALAEKAGGRGGGKGALAQGGGLDPRKAREALPGLLP GT:EXON 1|1-882:0| SW:ID SYA_THET2 SW:DE RecName: Full=Alanyl-tRNA synthetase; EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase; Short=AlaRS; SW:GN Name=alaS; OrderedLocusNames=TT_C1480; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Protein biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->882|SYA_THET2|0.0|100.0|882/882| GO:SWS:NREP 6 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| COIL:NAA 47 COIL:NSEG 1 COIL:REGION 728->774| SEG 217->232|qgpipgpgilkplpqk| SEG 362->376|rleeerfletleggl| SEG 473->485|aleaeaevlalla| SEG 546->569|arveegvlrvgervravvdprrrd| SEG 574->584|htathllhaal| SEG 611->625|peplkpeelervell| SEG 660->670|gevvrvvrveg| SEG 741->761|eaaleerlekllaelkekere| SEG 772->788|aalgggggasleekggl| SEG 846->867|ralaekaggrgggkgalaqggg| BL:PDB:NREP 1 BL:PDB:REP 5->439|1yfrA|e-111|51.7|412/448| RP:PDB:NREP 3 RP:PDB:REP 3->444|2cvsA|2e-57|10.4|431/657| RP:PDB:REP 464->713|2e1bA|1e-30|19.0|210/216| RP:PDB:REP 690->823|3c9iF|1e-07|6.1|131/221| RP:PFM:NREP 2 RP:PFM:REP 5->544|PF01411|e-152|52.6|519/546|tRNA-synt_2c| RP:PFM:REP 678->711|PF07973|5e-06|63.6|33/44|tRNA_SAD| HM:PFM:NREP 3 HM:PFM:REP 5->566|PF01411|2.4e-216|55.3|544/551|tRNA-synt_2c| HM:PFM:REP 663->712|PF07973|9.7e-19|61.4|44/44|tRNA_SAD| HM:PFM:REP 840->877|PF02272|7.9e-07|44.4|36/68|DHHA1| GO:PFM:NREP 11 GO:PFM GO:0000166|"GO:nucleotide binding"|PF01411|IPR018164| GO:PFM GO:0004813|"GO:alanine-tRNA ligase activity"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF01411|IPR018164| GO:PFM GO:0005737|"GO:cytoplasm"|PF01411|IPR018164| GO:PFM GO:0006412|"GO:translation"|PF01411|IPR018164| GO:PFM GO:0006419|"GO:alanyl-tRNA aminoacylation"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF07973|IPR012947| GO:PFM GO:0005737|"GO:cytoplasm"|PF07973|IPR012947| GO:PFM GO:0006412|"GO:translation"|PF07973|IPR012947| GO:PFM GO:0016876|"GO:ligase activity, forming aminoacyl-tRNA and related compounds"|PF07973|IPR012947| GO:PFM GO:0043039|"GO:tRNA aminoacylation"|PF07973|IPR012947| RP:SCP:NREP 4 RP:SCP:REP 1->254|1riqA2|1e-99|55.0|231/236|d.104.1.1| RP:SCP:REP 256->471|1riqA1|6e-58|42.2|204/212|a.203.1.1| RP:SCP:REP 464->544|2e1bA1|1e-11|28.4|67/87|b.43.3.6| RP:SCP:REP 585->736|1nyqA3|2e-23|14.0|150/179|d.67.1.1| HM:SCP:REP 1->254|1riqA2|4.1e-87|59.3|231/0|d.104.1.1|1/1|Class II aaRS and biotin synthetases| HM:SCP:REP 255->474|1riqA1|4.3e-66|51.2|217/0|a.203.1.1|1/1|Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)| HM:SCP:REP 562->736|1nyrA3|1.4e-48|46.1|167/179|d.67.1.1|1/1|ThrRS/AlaRS common domain| OP:NHOMO 1299 OP:NHOMOORG 1154 OP:PATTERN ---1-111-1-1--111111111111111111--11111111111-1-1-111111111111111-1- 1111111111111111111-1111111111111111111111111111111111111111111111112211-111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111 1111241-311-1111111-111111111111111111111111111111111111111111111111-2111111111111111111-12111111111111222123133332612221222242223D212222222221221222122223322122222232322322122222I2221222331212223222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 818 STR:RPRED 92.7 SQ:SECSTR ##HHHHHHHHHHHHHTcccEEEEcTTcccTTccccccccccHHHHHHHHHHHHHHHcccEcTTcTTHHHHHTcccccccccccccccEEEccEEEEcHHHHHHHHTTcEEEEGGGccHHHHHHHHHHHHHTEEEHHHHHHHHHHHHHHHcccEEHTcTTTTTccccHHHTccccTTccccccccTTcGGGEEccccccccHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHcccEEEEEcHHHHHHHTTccTTcHHHHHHHHHHHHHHHHHHHHcccTTcTTcGGGGTccTGGGGTccccccccHHHHHHHHHHHcccccccccccccTTHHHHTTcccHccccccccEEcccEEcHHHHHHHHHTTcccHHHHHHHHHTTTccTTcTTccHHHHHHTccTTcccHHHHHHHHHHHHTTccccccccEEcccccHHHHHHHHcccEEEEEEEEEccGGTccccccccTTccTTccEEEEccccccEEEEEEEEEEcccccccccccccccTTcccccEEEEETTTTEEEEEEEccTTcccEEEEccGGGccccccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHTTccEEEEccccccEEEEEEEccccGGGGHHHHHHHTHHHHHHHcccEEEEEccccEEEEETTccccTTTcTccccEEEEEEEEEEccccEEcccccccccGGGTccEEEEEEEEEETTEEEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH###HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH########################################################### DISOP:02AL 1-2, 381-390, 433-448| PSIPRED ccHHHHHHHHHHHHHHcccEEcccccccccccccEEEEEccHHccccEEccccccccccccccccccccccccccHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHcEEEEEEcccHHHHHHHHHHHcccHHHEEEcccccccccccccccccccccccccEEEEEccccccccccccccccccccEEEEEEcccEEEcccccccccccccccccccccccccHHHHHHHHcccccHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHccHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHccccHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHcccHHHHHccHHHHHHHHHccccccccccEEEEccEEEEEEEEcccEEEEEccccEEEEEEcccccccccccccccEEEEEEcccEEEEEEEEEccccEEEEEEEEcccccccccEEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHccccEEEccEEccccEEEEEEccccccHHHHHHHHHHHHHHHHccccEEEEEEcHHHHHHcccHHHcccccccEEEEEEEcccccccccccccccccccccccccccEEEEEEEEEccccEEEEEEcHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEcccccHHHHHHHHHHHHHHcccEEEEEccccEEEEEEEccccccccHHHHHHHHHHHccccccccHHHcccccccHHHHHHHHHHHcc //