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Thermus thermophilus HB27 (tthe0)
Gene : AAS81956.1
DDBJ      :             1-deoxy-D-xylulose 5-phosphate synthase
Swiss-Prot:DXS_THET2    RecName: Full=1-deoxy-D-xylulose-5-phosphate synthase;         EC=2.2.1.7;AltName: Full=1-deoxyxylulose-5-phosphate synthase;         Short=DXP synthase;         Short=DXPS;

Homologs  Archaea  41/68 : Bacteria  821/915 : Eukaryota  125/199 : Viruses  0/175   --->[See Alignment]
c.23.10c.36.1c.48.1
:615 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->610 2o1xB PDBj 0.0 62.7 %
:RPS:PDB   34->606 2e6kA PDBj 4e-58 19.9 %
:RPS:SCOP  36->250 1um9A  c.36.1.11 * 4e-13 10.9 %
:RPS:SCOP  244->465 2apjA1  c.23.10.7 * 2e-37 13.6 %
:RPS:SCOP  480->606 1dtwB2  c.48.1.2 * 2e-17 22.8 %
:HMM:SCOP  2->371 1w85A_ c.36.1.11 * 5.3e-77 39.3 %
:HMM:SCOP  283->474 1qgdA1 c.36.1.6 * 8.6e-62 44.9 %
:HMM:SCOP  480->606 1ni4B2 c.48.1.2 * 2.7e-25 42.4 %
:RPS:PFM   34->280 PF00456 * Transketolase_N 8e-08 31.9 %
:RPS:PFM   311->474 PF02779 * Transket_pyr 2e-21 40.3 %
:RPS:PFM   488->577 PF02780 * Transketolase_C 6e-10 41.1 %
:HMM:PFM   308->471 PF02779 * Transket_pyr 9.6e-43 32.5 163/178  
:HMM:PFM   484->599 PF02780 * Transketolase_C 3e-25 35.7 115/124  
:HMM:PFM   237->295 PF00456 * Transketolase_N 0.00017 35.7 56/333  
:HMM:PFM   111->175 PF02775 * TPP_enzyme_C 3.4e-06 32.2 59/150  
:HMM:PFM   10->37 PF06698 * DUF1192 0.00096 39.3 28/59  
:BLT:SWISS 1->615 DXS_THET2 0.0 100.0 %
:PROS 415->431|PS00802|TRANSKETOLASE_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS81956.1 GT:GENE AAS81956.1 GT:PRODUCT 1-deoxy-D-xylulose 5-phosphate synthase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION complement(1530086..1531933) GB:FROM 1530086 GB:TO 1531933 GB:DIRECTION - GB:PRODUCT 1-deoxy-D-xylulose 5-phosphate synthase GB:PROTEIN_ID AAS81956.1 GB:DB_XREF GI:46197543 LENGTH 615 SQ:AASEQ MILDKVNSPEDLKRLSLEELLLLAEEIRSEIIRVTAQNGGHLASSLGAVELVLALHRVFDSPRDRILFDVGHQAYAHKLVTGRKDRFHTLRKEGGISGFTKVSESPHDAITAGHASTSLANALGMVLARDLMGEDYHVVAVIGDGALTGGMALAALNKIGELQKRMLIVLNDNEMSISENVGALNKYFKELQIRKWVQDAEKLGKNILERISPQLFGLVDRAKEAAKLLLHQENPFYAWGIRYVGPVDGHDLKGLVHILEHLKALDGPTLLHVVTKKGKGYKVAEADPIYWHGPPGFDPKKPEKVSKGYTWSQAFGDAVTELAHMEPRLFVLTPAMREGSGLVRYSLEHPERYLDVGICEDVAVTTAAGLALRGMKPIVAIYSTFLQRAYDQVIHDVAIENLPVVFAIDRAGIVGADGATHHGVFDIAYLRTVPNLQIAAPKDALELRAMLKKALEVGGPVAIRYPRDNVERAPEGVWPEIAWGKWEVLKEGTEAYILAFGKTLKYALEAAGDDPRVGVVNARFLKPLDREMLRALSRYKLLTVEDHQRMGGFGSAVLEALNEMGLKPEVQVLGLPDRFFEHGAIPSLHRQAGIDAEGIRKALAAMGVAVVHERA GT:EXON 1|1-615:0| SW:ID DXS_THET2 SW:DE RecName: Full=1-deoxy-D-xylulose-5-phosphate synthase; EC=2.2.1.7;AltName: Full=1-deoxyxylulose-5-phosphate synthase; Short=DXP synthase; Short=DXPS; SW:GN Name=dxs; OrderedLocusNames=TT_C1614; SW:KW Complete proteome; Isoprene biosynthesis; Thiamine biosynthesis;Thiamine pyrophosphate; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->615|DXS_THET2|0.0|100.0|615/615| GO:SWS:NREP 3 GO:SWS GO:0008299|"GO:isoprenoid biosynthetic process"|Isoprene biosynthesis| GO:SWS GO:0009228|"GO:thiamin biosynthetic process"|Thiamine biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 415->431|PS00802|TRANSKETOLASE_2|PDOC00635| SEG 14->33|rlsleellllaeeirseiir| SEG 143->156|gdgaltggmalaal| BL:PDB:NREP 1 BL:PDB:REP 2->610|2o1xB|0.0|62.7|568/579| RP:PDB:NREP 1 RP:PDB:REP 34->606|2e6kA|4e-58|19.9|547/632| RP:PFM:NREP 3 RP:PFM:REP 34->280|PF00456|8e-08|31.9|204/275|Transketolase_N| RP:PFM:REP 311->474|PF02779|2e-21|40.3|159/172|Transket_pyr| RP:PFM:REP 488->577|PF02780|6e-10|41.1|90/122|Transketolase_C| HM:PFM:NREP 5 HM:PFM:REP 308->471|PF02779|9.6e-43|32.5|163/178|Transket_pyr| HM:PFM:REP 484->599|PF02780|3e-25|35.7|115/124|Transketolase_C| HM:PFM:REP 237->295|PF00456|0.00017|35.7|56/333|Transketolase_N| HM:PFM:REP 111->175|PF02775|3.4e-06|32.2|59/150|TPP_enzyme_C| HM:PFM:REP 10->37|PF06698|0.00096|39.3|28/59|DUF1192| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF02780|IPR005476| GO:PFM GO:0008152|"GO:metabolic process"|PF02780|IPR005476| RP:SCP:NREP 3 RP:SCP:REP 36->250|1um9A|4e-13|10.9|202/331|c.36.1.11| RP:SCP:REP 244->465|2apjA1|2e-37|13.6|206/244|c.23.10.7| RP:SCP:REP 480->606|1dtwB2|2e-17|22.8|123/138|c.48.1.2| HM:SCP:REP 2->371|1w85A_|5.3e-77|39.3|313/0|c.36.1.11|1/1|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 283->474|1qgdA1|8.6e-62|44.9|187/195|c.36.1.6|1/1|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 480->606|1ni4B2|2.7e-25|42.4|125/138|c.48.1.2|1/1|TK C-terminal domain-like| OP:NHOMO 1873 OP:NHOMOORG 987 OP:PATTERN 11-1--1111111111-122111---11-1-1---11111111-----------11-111-122--11 113361111111-122233-31113332333222223373334523432212655223113232527554211111114222311122222311111-1234452435171211112212222212212222224222212111223331224222211221122143333212112111121111112212222222222222222222333222222432231122311331111111111111111-----2-----21-211221--1----2212221122-11111111111111111111111111-11111222221224222222243514222222113--4242222222212223232333231111111111114442132222411221222212-33333433222-3331333232431411133132334322222222224422222111-----1----1----1---11-----22151322111422122222223323222212113121111111211112132221121111121111111111121-21221111131111344333424223222111112111111111111111111111111121112111224222212111221122231--31111--11121222311111111111-111111111111111111333321111322222222222222211111111112212222222221111---------1111111122111111111133323211112111111122111221221111111111-11111111111111222222211111111132223344--------111-----------1------1------2322223232121 12--21--311---121-------------------------------11112211---111----1111-1---11-11----11------111-11-1---111--2122421312-2233132272Dd4-64612113135--11123214-222311-1221-611A11422231S2223376E81641211112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 613 STR:RPRED 99.7 SQ:SECSTR cHHHHHHHHHHHHHHHHHHHTTcHHHHHHHHTTHHHHTccccHHHHHHHHHHHHTTccccTTccEEEEccGGGHHHHHHHTTccccHHHHTTTTccccccccTTcTTcccccccTTHHHHHHHHHHHHHHHHHHHHccEEEEEcHHHHcHHHHHHHHHHHHTTcTTEEEEEEccEETTEEGGcHHHHHHGTccccHHHHHHHTTcEEEEEccTTcHHHHHHHHHHHEccTTTTcTTTTcGGGTccccHHHHHHHHHHHHTcccTTcccHHHHHHHcHHHHHHHHHHHHHHHHHHHHHcHHHcccccccccHHHHHHHHHHHHGGGcTTEEEEHHHHTcccTTccccTTcTccEEEccccHHHHHHHHHHHHHcccEEEEEEEEEEGGGGGGHHHHHHHHHTcccEEEEEcccGGcTTcTTTccccHHHHHTcTTTcEEEccccHHHHHHHHHHHHHccccEEEEccccccccccHHHGGGGGccEEEEccccccEEEEEcTTHHHHHHHHHHTTccEEEEEcccHHHHHTccHHHHHHHccEEEEcccccTTGGGTccEEEccHHcccccEEEEccccccccccTTHHHHHTTccHHHHHHHHHTTTTccccc## DISOP:02AL 612-615| PSIPRED ccccccccHHHHHHccHHHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHccccccccEEEEEcccHHHHHHHHHccHHHHHHHHHcccccccccccccccEEEccccHHHHHHHHHHHHHHHHHHccccEEEEEEEcccccHHHHHHHHHHHHHHcccEEEEEEcccccccccHHHHHHHHHHHHHccHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHccccccccccHHHccccEEcccccccHHHHHHHHHHHHHccccEEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHccEEEEEEccccccccHHHHHHcccccEEEccHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEcccccccccccccccHHHHHHHHHcccEEEEEccHHHHHHHHHHHHHccccEEEEEccccccccccccccccccccEEEEEccccEEEEEEcHHHHHHHHHHHccccEEEEcccEEccccHHHHHHHHcccEEEEccccccccHHHHHHHHHHHccccccEEEEEEcccccccccHHHHHHHHcccHHHHHHHHHHHHHHHHcccc //