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Thermus thermophilus HB27 (tthe0)
Gene : AAS82148.1
DDBJ      :             DNA polymerase III alpha subunit
Swiss-Prot:             

Homologs  Archaea  4/68 : Bacteria  909/915 : Eukaryota  3/199 : Viruses  3/175   --->[See Alignment]
a.4.6b.29.1b.40.4b.42.4b.86.1c.6.3d.58.1d.95.2
:2067 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->771,1660->2051 3e0dA PDBj 0.0 89.7 %
:BLT:PDB   768->859 2in8A PDBj 2e-11 39.1 %
:BLT:PDB   968->1051 1dq3A PDBj 1e-04 29.8 %
:BLT:PDB   1151->1192 1mi8A PDBj 6e-05 40.5 %
:BLT:PDB   1187->1251 3e0dA PDBj 3e-21 69.2 %
:BLT:PDB   1268->1337,1622->1662 1mi8A PDBj 2e-09 39.7 %
:RPS:PDB   5->770,1662->2052 3e0dA PDBj 0.0 91.7 %
:RPS:PDB   763->1190 1dq3A PDBj 2e-25 14.6 %
:RPS:PDB   1175->1239 3e0dA PDBj 1e-15 68.2 %
:RPS:PDB   1267->1661 1dq3A PDBj 2e-18 13.0 %
:RPS:SCOP  44->169 1q16B  d.58.1.5 * 2e-24 17.5 %
:RPS:SCOP  339->484 1r8nA  b.42.4.1 * 3e-31 15.2 %
:RPS:SCOP  461->565 1fc3A  a.4.6.3 * 3e-21 10.5 %
:RPS:SCOP  744->767,1633->1770 1kitA2  b.29.1.8 * 4e-25 9.2 %
:RPS:SCOP  768->865 1at0A  b.86.1.1 * 1e-14 19.6 %
:RPS:SCOP  965->1051 1dfaA3  d.95.2.2 * 2e-17 16.1 %
:RPS:SCOP  1138->1190 1am2A  b.86.1.2 * 1e-07 24.1 %
:RPS:SCOP  1179->1251 1kitA2  b.29.1.8 * 3e-10 8.1 %
:RPS:SCOP  1268->1339 1am2A  b.86.1.2 * 5e-13 27.5 %
:RPS:SCOP  1436->1528 1dfaA3  d.95.2.2 * 9e-08 16.0 %
:RPS:SCOP  1619->1661 1am2A  b.86.1.2 * 3e-11 27.3 %
:RPS:SCOP  1848->1942 1asyA1  b.40.4.1 * 1e-09 15.3 %
:HMM:SCOP  6->278 1m65A_ c.6.3.1 * 1e-30 25.8 %
:HMM:SCOP  767->1190 1am2A_ b.86.1.2 * 1.4e-41 41.3 %
:HMM:SCOP  1238->1661 1am2A_ b.86.1.2 * 5.1e-46 41.3 %
:RPS:PFM   8->143 PF02811 * PHP 2e-14 44.4 %
:RPS:PFM   374->771 PF07733 * DNA_pol3_alpha e-134 61.9 %
:RPS:PFM   785->895 PF07591 * DUF1557 7e-07 27.9 %
:RPS:PFM   1187->1215 PF07733 * DNA_pol3_alpha 5e-06 58.6 %
:HMM:PFM   363->770 PF07733 * DNA_pol3_alpha 6.8e-156 54.8 385/422  
:HMM:PFM   9->193 PF02811 * PHP 1.1e-45 40.4 171/175  
:HMM:PFM   1893->1964 PF01336 * tRNA_anti 1e-08 30.4 69/76  
:HMM:PFM   768->839 PF01079 * Hint 7.4e-05 28.2 71/217  
:BLT:SWISS 1->771,1660->2067 DPO3A_THEAQ 0.0 91.1 %
:BLT:SWISS 767->1190 RECA_MYCTU 2e-32 30.6 %
:BLT:SWISS 1187->1251 DPO3A_THEAQ 8e-21 69.2 %
:BLT:SWISS 1268->1560 DNAB_RHOMR 8e-18 31.9 %
:BLT:SWISS 1619->1662 DNAB_RHOMR 2e-11 61.4 %
:REPEAT 2|725->1191|1203->1662
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS82148.1 GT:GENE AAS82148.1 GT:PRODUCT DNA polymerase III alpha subunit GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION 1712094..1718297 GB:FROM 1712094 GB:TO 1718297 GB:DIRECTION + GB:PRODUCT DNA polymerase III alpha subunit GB:PROTEIN_ID AAS82148.1 GB:DB_XREF GI:46197736 LENGTH 2067 SQ:AASEQ MGRKLRFAHLHQHTQFSLLDGAAKLSDLLKWVKETTPEDPALAMTDHGNLFGAVEFYKKATEMGIKPILGYEAYVAAESRFDRKRGKGLDGGYFHLTLLAKDFTGYQNLVRLASRAYLEGFYEKPRIDREILREHAEGLIALSGCLGAEIPQFILQDRLDLAEARLNEYLSIFKDRFFIEIQNHGLPEQKKVNEVLKEFARKYGLGMVATNDGHYVRKEDARAHEVLLAIQSKSTLDDPGRWRFPCDEFYVKTPEEMRAMFPEEEWGDEPFDNTVEIARMCNVELPIGDKMVYRIPRFPLPEGRTEAQYLMELTFKGLLRRYPDRITEGFYREVFRLLGKLPPHGDGEALAEALAQVEREAWERLMKSLPPLAGVKEWTAEAIFHRALYELSVIERMGFPGYFLIVQDYINWARRNGVSVGPGRGSAAGSLVAYAVGITNIDPLRFGLLFERFLNPERVSMPDIDTDFSDRERDRVIQYVRERYGEDKVAQIGTLGSLASKAALKDVARVYGIPHKKAEELAKLIPVQFGKPKPLQEAIQVVPELRAEMEKDPKVREVLEVAMRLEGLNRHASVHAAGVVIAAEPLTDLVPLMRDQEGRPVTQYDMGAVEALGLLKMDFLGLRTLTFLDEVKRIVKASQGVELDYDALPLDDPKTFALLSRGETKGVFQLESGGMTATLRGLKPRRFEDLIAILSLYRPGPMEHIPTYIRRHHGLEPVSYSEFPHAEKYLKPILDETYGIPVYQEQIMQIASAVAGYSLGEADLLRRCLAEGSLVLDAATGQRVPIEKVRPGMEVFSLGPDYRLYRVPVLEVLESGVREVVRLRTRSGRTLVLTPDHPLLTPEGWKPLCDLPLGTPIAVPAELPVAGHLAPPEERVTLLALLLGDGNTKLSGRRGTRPNAFFYSKDPELLAAYRRCAEALGAKVKAYVHPTTGVVTLATLAPRPGAQDPVKRLVVEAGMVAKAEEKRVPEEVFRYRREALALFLGRLFSTDGSVEKKRISYSSASLGLAQDVAHLLLRLGITSQLRSRGPRAHEVLISGREDILRFAELIGPYLLGAKRERLAALEAEARRRLPGQGWHLRLVLPAVAYRVSEAKRRSGFSWSEAGRRVAVAGSCLSSGLNLKLPRRYLSRHRLSLLGEAFADPGLEALAEGQVLWDPIVAVEPAGKARTFDLRVPPFANFVSEDLVVHNSMGKKKVEEMKSHRERFVQGAKERGVPEEEANRLFDMLEAFANYGFNKCLPARARVVDWCTGRVVRVGEIVRGEAKGVWVVSLDEARLRLVPRPVVAAFPSGKAQVYALRTATGRVLEATANHPVYTPEGWRPLGTLAPGDYVALPRHLSYRPSLHLEGHELDLLGFALAEGHLRHPSGVYLYTSSEEELAAMEEALRAFPNTRIRVVWRRGVAHVYVGRVDRRQEAGAVAFLRRMGLLGLDAKTKRLPEAVFGLPPEEVARFLGRLWTGDGGVDPKGRLIHYATASKELAWGVQHLLLRLGLQSRLVEKRFSGGYKGYAVYLLGGLEAARRFAETVGPYLVGKRRQDLEALLASWEKAGRSTGDVLPLAFLEEVRAAVAEVAQGQVADLLREAGLAEGLLCLGRGRRGLSRATVGRLAALTGSLALLRLAEAEVYWDRVEAVEPLGEEEVFDLTVEGTHTFVAEDVIVHNSHAAAYSLLSYQTAYVKAHYPVEFMAALLSVERHDSDKVAEYIRDARAMGIEVLPPDVNRSGFDFLVQGRQILFGLSAVKNVGEAAAEAILRERERGGPYRSLGDFLKRLDEKVLNKRTLEFLIKAGALDGFGERARLLASLEGLLKWAAENREKARSGMMGLFSEVEEPPLAEAAPLDEITRLRYEKEALGIYVSGHPILRYPGLRETATCTLEELPHLARDLPPRSRVLLAGMVEEVVRKPTKSGGMMARFVLSDETGALEAVAFGRAYDQVSPRLKEDTPVLVLAEVEREEGGVRVLAQAVWTYEELEQVPRALEVEVEASLLDDRGVAHLKSLLDEHAGTLPLYVRVQGAFGEALLALREVRVGEEALGALEAAGFRAYLLPDREVLLQGGQAGEAQEAVPF GT:EXON 1|1-2067:0| BL:SWS:NREP 5 BL:SWS:REP 1->771,1660->2067|DPO3A_THEAQ|0.0|91.1|1178/1220| BL:SWS:REP 767->1190|RECA_MYCTU|2e-32|30.6|412/790| BL:SWS:REP 1187->1251|DPO3A_THEAQ|8e-21|69.2|65/1220| BL:SWS:REP 1268->1560|DNAB_RHOMR|8e-18|31.9|281/941| BL:SWS:REP 1619->1662|DNAB_RHOMR|2e-11|61.4|44/941| NREPEAT 1 REPEAT 2|725->1191|1203->1662| SEG 1054->1073|llgakrerlaaleaearrrl| SEG 1124->1137|lprrylsrhrlsll| SEG 1252->1264|grvvrvgeivrge| SEG 1345->1356|lhlegheldllg| SEG 1377->1389|eeelaameealra| SEG 1483->1498|gvqhlllrlglqsrlv| SEG 1563->1578|eevraavaevaqgqva| SEG 1580->1603|llreaglaegllclgrgrrglsra| SEG 1744->1759|geaaaeailrerergg| SEG 1829->1839|eepplaeaapl| SEG 1945->1962|vlvlaevereeggvrvla| SEG 2029->2040|geealgaleaag| BL:PDB:NREP 6 BL:PDB:REP 5->771,1660->2051|3e0dA|0.0|89.7|1105/1148| BL:PDB:REP 768->859|2in8A|2e-11|39.1|92/139| BL:PDB:REP 968->1051|1dq3A|1e-04|29.8|84/454| BL:PDB:REP 1151->1192|1mi8A|6e-05|40.5|42/141| BL:PDB:REP 1187->1251|3e0dA|3e-21|69.2|65/1148| BL:PDB:REP 1268->1337,1622->1662|1mi8A|2e-09|39.7|109/141| RP:PDB:NREP 4 RP:PDB:REP 5->770,1662->2052|3e0dA|0.0|91.7|1103/1148| RP:PDB:REP 763->1190|1dq3A|2e-25|14.6|417/454| RP:PDB:REP 1175->1239|3e0dA|1e-15|68.2|65/1148| RP:PDB:REP 1267->1661|1dq3A|2e-18|13.0|392/454| RP:PFM:NREP 4 RP:PFM:REP 8->143|PF02811|2e-14|44.4|126/177|PHP| RP:PFM:REP 374->771|PF07733|e-134|61.9|391/428|DNA_pol3_alpha| RP:PFM:REP 785->895|PF07591|7e-07|27.9|111/126|DUF1557| RP:PFM:REP 1187->1215|PF07733|5e-06|58.6|29/428|DNA_pol3_alpha| HM:PFM:NREP 4 HM:PFM:REP 363->770|PF07733|6.8e-156|54.8|385/422|DNA_pol3_alpha| HM:PFM:REP 9->193|PF02811|1.1e-45|40.4|171/175|PHP| HM:PFM:REP 1893->1964|PF01336|1e-08|30.4|69/76|tRNA_anti| HM:PFM:REP 768->839|PF01079|7.4e-05|28.2|71/217|Hint| GO:PFM:NREP 7 GO:PFM GO:0003824|"GO:catalytic activity"|PF02811|IPR004013| GO:PFM GO:0005737|"GO:cytoplasm"|PF07733|IPR011708| GO:PFM GO:0006260|"GO:DNA replication"|PF07733|IPR011708| GO:PFM GO:0008408|"GO:3'-5' exonuclease activity"|PF07733|IPR011708| GO:PFM GO:0005737|"GO:cytoplasm"|PF07733|IPR011708| GO:PFM GO:0006260|"GO:DNA replication"|PF07733|IPR011708| GO:PFM GO:0008408|"GO:3'-5' exonuclease activity"|PF07733|IPR011708| RP:SCP:NREP 12 RP:SCP:REP 44->169|1q16B|2e-24|17.5|126/509|d.58.1.5| RP:SCP:REP 339->484|1r8nA|3e-31|15.2|138/185|b.42.4.1| RP:SCP:REP 461->565|1fc3A|3e-21|10.5|105/119|a.4.6.3| RP:SCP:REP 744->767,1633->1770|1kitA2|4e-25|9.2|155/197|b.29.1.8| RP:SCP:REP 768->865|1at0A|1e-14|19.6|97/145|b.86.1.1| RP:SCP:REP 965->1051|1dfaA3|2e-17|16.1|87/117|d.95.2.2| RP:SCP:REP 1138->1190|1am2A|1e-07|24.1|53/181|b.86.1.2| RP:SCP:REP 1179->1251|1kitA2|3e-10|8.1|73/197|b.29.1.8| RP:SCP:REP 1268->1339|1am2A|5e-13|27.5|72/181|b.86.1.2| RP:SCP:REP 1436->1528|1dfaA3|9e-08|16.0|92/117|d.95.2.2| RP:SCP:REP 1619->1661|1am2A|3e-11|27.3|43/181|b.86.1.2| RP:SCP:REP 1848->1942|1asyA1|1e-09|15.3|85/137|b.40.4.1| HM:SCP:REP 6->278|1m65A_|1e-30|25.8|229/0|c.6.3.1|1/1|PHP domain-like| HM:SCP:REP 767->1190|1am2A_|1.4e-41|41.3|184/199|b.86.1.2|1/2|Hedgehog/intein (Hint) domain| HM:SCP:REP 1238->1661|1am2A_|5.1e-46|41.3|189/199|b.86.1.2|2/2|Hedgehog/intein (Hint) domain| OP:NHOMO 1412 OP:NHOMOORG 919 OP:PATTERN ------------------------------------1-----------------21--2--------- 3222222222222222244-42112344444222223223222142222211242221113222113232111112111111211111111111111112131224141311111111111111111111-11111111111111222222221122111111232223331111111111112211111132222222222222233222222322322222111222212122222222222222222422222111121211122121211112221111111111111111111111111111111111111111111122232232222222222222213122113212122121212322222112212322211111222223222222222122221213122223222322-3442332333232322232221222221111111124221211111111111111111111111111111111222212221242532232222333223222224222221122223422222231222211111111111111222222131111111111121211112122222212111111111111111111111111122111222121112111111111112112111111133111111111111111111111111-11111111111111111111111111111111111111211111111111111112112222111111111111111121211111111111-11111111111111111222222222222222221111111111111111111222222222222222111111111111111111111111112112-12111111111111111112212222222121 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1--------------3---------- --------------1-----------------------------------------------------------------1---------------------------------------------1------------------------------------------------ STR:NPRED 2020 STR:RPRED 97.7 SQ:SECSTR TTccccccccccccTTcTTTccccHHHHHHHHHHHcccccEEEEEEETccTTHHHHHHHHHTTTcEEEEEEEEEEEcccTTccccccHHHHHEEEEEEEEccHHHHHHHHHHHHHHHHTccccccEEcHHHHHHTcTTEEEEcccTTcHHHHHHHTTcHHHHHHHHHHHHHHHGGGEEEEEcccccHHHHHHHHHHHHHHHHTTccEEEccccccccGGGHHHHHHHHHHHTTccccccccccccccccccccHHHHHHHccHHHHccHHHHHHHHHHHTcccccccTTcccccccccccTccccHHHHHHHHHHHHHHHHcTTTccHHHHHHHHTTcHHHHHHHcHHHHHHHHHHccHHHHTTTTT########ccccHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHHHHHHTTTcccccccGGGGGcHHHHHTTcccccTTTTTccHHHHccTTcccccccEEEEETTTHHHHHHHHHHHHcTTTEEEEEEEccccHHHHHHHHHHHTTccHHHHHHHHTTccccccccccTTTTTcccTTTTTHHHHcHHHHHHHHHHHHcTTccccEEEcccEEEEccccGGGTccEEEcTTccEEEEEEHHHHHTTTcEEEEEEEEHHHHHHHHHHHHHHHHHcccccGGGccTTcHHHHHHHHTTccTTcTTcccHHHHHHHHHHccccHHHHHHHHHHccTTGGGHHHHHHHHHTTccccccTTcTTTHHHHHHHHGGGTTccccHHHHHHHHHHHccccHHHHHHHHHHHHGcEEEEccTTTTEEEEEcTTcccEEEEEETTTEEEEEEEEEEEEcTTccEEEEEETTccEEEEcTTcEEEEEcTTccEEEEETTTccTTcEEcccccccccccHHHHHHHHHHHHEEEEEEEcccTTcTTcccEEEEEEEEEccHHHHHHHHHHHHHHHHHccccccEEccccEEEEEccHHHHHHHHHHHTTGGGcccHHHHTTcHHHHHHHHHHHHHHHcEEETTEEEEEEccHHHHHHHHHHHHTTTcccEEEccccEEEEEEEccHHHHHHHHHHTGGGcccHHHHHHHHHHHHccccccEEcccHHHHHHHHHTTTcEEEEETTEEEEEETTEEEEcTTHHHHccEEH####HHHHHHHHHHHHHHccHHHHHHHHHHHHcEEEEEEEEEccEEEEEEEETTTcEEEEEcEEEEcHHHHTcTTTHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHTTccccHHHHHHHHHHHHHH##############ccEEEEEEcTTTccEEEEEEEEEEEEEEEEEEEEEETTccEEEEETTcEEEEEETEEETTTccTTcEEEEEcccccccccccccccHHHHHHHHHHEEEEEEEcccTTcccEEEEEEEEEccHHHHHHHHHHHHHHHccccccEEccccEEEEEccHHHHHHHHHHTTGGGcccHHHHTTcHHHHHHHHHHHHHHHcEEETTTEEEEEEEccHHHHHHHHHHHHTTTcccEEEEEEccccccEEEEEEEccHHHHHHHHHHTGGGcccHHHHHHHHHHHHcccccccEEcccHHHHHHHHHTTTcEEEEETTEEEEEETTEEEEcTTHHHHccEEHHHHHHHHHHHHHHHccHHHHHccEEEEEEEEEEEEEEEEEEEEEETTTcEEEETcEEEEcHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHTTTcHHHHHHHHHHHHTTcccEEcccTTTcccccEEETTEEEcccTTcccccHHHHHHHHHHHHHccccccHHHHHHHccTTTccHHHHHHHHHHTTTGGGccHHHHHHHHHHHHHHHHHHHHHHTTcccccccccccccccccccccHHHHHHHHHHHHcccccccGGGTcHHHHHHccccGGGHHHHHcccccccEEEEEEEEcccEEEEcTTccEcccEEEEETTEEEEEccETHHHHHHHHHccTTcE######EEEEEEEccEEEEEEccHHHHTTccccEEEEEcccccTTTcccHHHHHHHTcEEEEEEEEEEEccccEEEEEEEEEEEccTHHHHHTTTTcEEEEccccTTc############### DISOP:02AL 1-4, 779-786, 1815-1827, 2061-2063| PSIPRED ccccccEEEEEccccHHHHHHcccHHHHHHHHHHcccccEEEEEEcccHHHHHHHHHHHHHHccccEEEEEEEEEEcccccccccccccccccccEEEEEEcHHHHHHHHHHHHHHHHccccccccccHHHHHHHcccEEEEccccccHHHHHHHcccHHHHHHHHHHHHHHccccEEEEEEEcccHHHHHHHHHHHHHHHHHcccEEEccccccccHHHHHHHHHHHHHHccccccccccccccccccccccHHHHHHHHHHcccHHHHHHHHHHHHHHHEEccccccccccccccccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHccccccEEEHHHHHHHHHHccccccccccccHHHHHHHHHHccccccccccccEEEccccccccccEEEcccccccHHHHHHHHHHHcccccEEEEEEEEEHHHHHHHHHHHHHHcccHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHcccccccccccEEEEEcccccEEEcccEEcccccEEEEccHHHHHHcccEEEEEEccccHHHHHHHHHHHHHHccccccHHHcccccHHHHHHHccccEEEEcccccHHHHHHHHHcccccHHHHHHHHHHcccccHHHccHHHHHccccccccccccccccHHHHHHHHHHccccccHHHHHHHHHHHcccccccccHHHHHccccHHHHHHHHccccHHHHHHHHHHHHHHccccccccccEEEEEEEcccEEEEEEEccccEEEEEcccEEEEccccEEEEEEcccccEEccccccccccccccHHHHHHHHHHHHccEEcccccccccEEEEEccccHHHHHHHHHHHHHccccEEEEEEccccEEEEEEEcccHHHHHHHHHHHHHcccccccccccccHHHHcccHHHHHHHHHHHHHcccEEEccEEEEEEccHHHHHHHHHHHHHccEEEEEEEcccEEEEEEEEcHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHccccEEEcccHHHHHHHHHHHHHHHcHHHHHHHcccccccccccEEEcccEEEEHEEEHHHccccHHHHHHHHHccccHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHcccccccccccccccEEEEccccEEEEHHHHHccccccEEEEEEccccEEEEEEEHHHHHccccccEEEEEEccccEEEEEcccEEEEEcccEEEEEEEcccEEEEcccccccccccccHHHHHHHHHHHcccEEEccccEEEEEccHHHHHHHHHHHHHHcccccEEEccccccEEEcEEEEcccccHHHHHHHHcccccccccccHHHHHHHHccHHHHHHHHHHHHHcccEEcccccEEEEEEccHHHHHHHHHHHHHccccEEEEEEEccccEEEEEEEEEccHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccccHHHHHHcccccEEEcccHHHHHHHHccHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHcccccHHHHHHHHHHHHHHHHccccHHHHHHHHHHcccccHHHHHHHHHHHHHcccEEEcccccccccEEEEEccEEEccHHHcccccHHHHHHHHHHHHcccccccHHHHHHHcccccccHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccccHHHHHHHHHHHHcEEEEcccHHHHHHHHHHHcccHHHHHHHHHccccccEEEEEEEEEEEEEEccccccEEEEEEEEccccEEEEEEcHHHHHHHHHHHccccEEEEEEEEEEEccEEEEEEEEcccHHHHHHHHccEEEEEEHHcccHHHHHHHHHHHHHcccccEEEEEEEccccEEEEEcccccccHHHHHHHHHcccccccccccEEEEEccccccHHHcccc //