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Thermus thermophilus HB27 (tthe0)
Gene : AAS82263.1
DDBJ      :             dimethyladenosine transferase
Swiss-Prot:KSGA_THET2   RecName: Full=Dimethyladenosine transferase;         EC=2.1.1.-;AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase;AltName: Full=16S rRNA dimethylase;AltName: Full=High level kasugamycin resistance protein ksgA;AltName: Full=Kasugamycin dimethyltransferase;

Homologs  Archaea  57/68 : Bacteria  902/915 : Eukaryota  183/199 : Viruses  0/175   --->[See Alignment]
c.66.1
:271 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->268 3fuxC PDBj e-148 99.2 %
:RPS:PDB   20->199 3bt7A PDBj 4e-13 11.7 %
:RPS:PDB   208->265 3doaA PDBj 2e-04 16.1 %
:RPS:SCOP  27->268 1qyrA  c.66.1.24 * 1e-44 36.3 %
:HMM:SCOP  14->272 1i4wA_ c.66.1.24 * 4.3e-60 44.1 %
:RPS:PFM   21->263 PF00398 * RrnaAD 3e-39 52.5 %
:HMM:PFM   23->246 PF00398 * RrnaAD 3.2e-42 33.6 223/262  
:BLT:SWISS 1->271 KSGA_THET2 e-153 100.0 %
:PROS 50->77|PS01131|RRNA_A_DIMETH

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS82263.1 GT:GENE AAS82263.1 GT:PRODUCT dimethyladenosine transferase GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION complement(1829165..1829980) GB:FROM 1829165 GB:TO 1829980 GB:DIRECTION - GB:PRODUCT dimethyladenosine transferase GB:PROTEIN_ID AAS82263.1 GB:DB_XREF GI:46197851 LENGTH 271 SQ:AASEQ MSKLASPQSVRALLERHGLFADKRFGQNFLVSEVHLRRIVEAARPFTGPVFEVGPGLGALTRALLEAGAEVTAIEKDLRLRPVLEETLSGLPVRLVFQDALLYPWEEVPQGSLLVANLPYHIATPLVTRLLKTGRFARLVFLVQKEVAERMTARPKTPAYGVLTLRVAHHAVAERLFDLPPGAFFPPPKVWSSLVRLTPTGAPDDPGLFRLVEAAFGKRRKTLLNALAAAGYPKARVEEALRALGLPPRVRAEELDLEAFRRLREGLEGAV GT:EXON 1|1-271:0| SW:ID KSGA_THET2 SW:DE RecName: Full=Dimethyladenosine transferase; EC=2.1.1.-;AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase;AltName: Full=16S rRNA dimethylase;AltName: Full=High level kasugamycin resistance protein ksgA;AltName: Full=Kasugamycin dimethyltransferase; SW:GN Name=ksgA; OrderedLocusNames=TT_C1921; SW:KW Antibiotic resistance; Complete proteome; Methyltransferase;RNA-binding; rRNA processing; S-adenosyl-L-methionine; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->271|KSGA_THET2|e-153|100.0|271/271| GO:SWS:NREP 5 GO:SWS GO:0046677|"GO:response to antibiotic"|Antibiotic resistance| GO:SWS GO:0008168|"GO:methyltransferase activity"|Methyltransferase| GO:SWS GO:0003723|"GO:RNA binding"|RNA-binding| GO:SWS GO:0006364|"GO:rRNA processing"|rRNA processing| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 50->77|PS01131|RRNA_A_DIMETH|PDOC00871| BL:PDB:NREP 1 BL:PDB:REP 4->268|3fuxC|e-148|99.2|265/265| RP:PDB:NREP 2 RP:PDB:REP 20->199|3bt7A|4e-13|11.7|180/369| RP:PDB:REP 208->265|3doaA|2e-04|16.1|56/266| RP:PFM:NREP 1 RP:PFM:REP 21->263|PF00398|3e-39|52.5|238/256|RrnaAD| HM:PFM:NREP 1 HM:PFM:REP 23->246|PF00398|3.2e-42|33.6|223/262|RrnaAD| GO:PFM:NREP 3 GO:PFM GO:0000154|"GO:rRNA modification"|PF00398|IPR001737| GO:PFM GO:0000179|"GO:rRNA (adenine-N6,N6-)-dimethyltransferase activity"|PF00398|IPR001737| GO:PFM GO:0008649|"GO:rRNA methyltransferase activity"|PF00398|IPR001737| RP:SCP:NREP 1 RP:SCP:REP 27->268|1qyrA|1e-44|36.3|237/252|c.66.1.24| HM:SCP:REP 14->272|1i4wA_|4.3e-60|44.1|256/0|c.66.1.24|1/1|S-adenosyl-L-methionine-dependent methyltransferases| OP:NHOMO 1278 OP:NHOMOORG 1142 OP:PATTERN --111111--------1111111111111111111111111111111111111111111111111-11 1111211111121211111-1111121111111111111111-11111111111111111111111211111111111111111111111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111---1111-1111111111111111111111111122111111111111111111111121111111111111111111211111111111111111111111111111111111111422111111111111111111111111211111111111111111113111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111 22-1221-411111111111111111-11-1111111111111---11111-1-11111111111111111111111-1111111111-1211111111111122212-2432223-222112222-21272-2222-12312311221221231222211221221423142222122F2222222331322232223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 271 STR:RPRED 100.0 SQ:SECSTR cccGGGcHHHHHHHHHTTEEETTccccccHHHHHHHHHHHHHHTTTcccEEEEccTTcHHHHHHGGGccEEEEEcccHHHHHHHHHHHHTcccEEEEccccHHHHHHHccccccTTGGGccGGGccEEEEEEcccTTcccHHHHHHHTTccEEEEEEccHHHHHHHHHHHHHHEEEEEEEEEcccTTccccEEEEEEEEEEEEEEccccEEEEEEEEEccccHHHHHHHHTTTcHHHTTTcccEEEEcccccccccccccccTTccEETcc DISOP:02AL 1-5| PSIPRED ccccccHHHHHHHHHHcccccccccccEEEccHHHHHHHHHHHccccccEEEEcccccHHHHHHHHHccEEEEEEccHHHHHHHHHHccccccEEEEccHHHccccccccccEEEEEcccccHHHHHHHHHHcccccEEEEEEHHHHHHHHcccccccHHHHHHHHHHHHHcEEEEEEEccccccccccEEEEEEEEEEcccccHHHHHHHHHHHHccccHHHHHHHHHccccHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHc //