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Thermus thermophilus HB27 (tthe0)
Gene : AAS82272.1
DDBJ      :             ribonucleoside-diphosphate reductase alpha chain
Swiss-Prot:             

Homologs  Archaea  50/68 : Bacteria  324/915 : Eukaryota  81/199 : Viruses  5/175   --->[See Alignment]
b.86.1c.7.1d.95.2g.41.3
:1800 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   57->172 2zlgA PDBj 6e-06 27.7 %
:BLT:PDB   207->274,1293->1597 1xjfA PDBj 7e-48 42.2 %
:BLT:PDB   738->886 1xjnB PDBj 1e-07 29.6 %
:BLT:PDB   915->993 2in9A PDBj 4e-07 39.7 %
:RPS:PDB   57->173,1291->1593 2cvtA PDBj 1e-56 18.8 %
:RPS:PDB   173->270 2cvwA PDBj 3e-12 23.3 %
:RPS:PDB   299->736 1dq3A PDBj 2e-26 13.5 %
:RPS:PDB   736->942 2cvtA PDBj 5e-31 21.4 %
:RPS:PDB   1033->1292 2cw8A PDBj 2e-19 17.0 %
:RPS:SCOP  57->265,1232->1605 1l1lA  c.7.1.4 * 3e-73 18.4 %
:RPS:SCOP  298->428,701->736 1am2A  b.86.1.2 * 2e-14 20.6 %
:RPS:SCOP  516->607 1dfaA3  d.95.2.2 * 5e-15 17.4 %
:RPS:SCOP  734->886 1r1rA2  c.7.1.2 * 3e-27 19.5 %
:RPS:SCOP  886->1009 1am2A  b.86.1.2 * 2e-14 22.6 %
:RPS:SCOP  1121->1246 1dfaA3  d.95.2.2 * 8e-11 13.4 %
:RPS:SCOP  1774->1796 1pftA  g.41.3.1 * 1e-04 43.5 %
:HMM:SCOP  5->152 1l1lA_ c.7.1.4 * 1.9e-15 35.0 %
:HMM:SCOP  207->273 1peqA2 c.7.1.2 * 1.9e-06 42.4 %
:HMM:SCOP  298->736 1am2A_ b.86.1.2 * 2.6e-38 36.2 %
:HMM:SCOP  734->886 1peqA2 c.7.1.2 * 2.5e-24 35.5 %
:HMM:SCOP  885->1292 1am2A_ b.86.1.2 * 3.1e-39 39.7 %
:HMM:SCOP  1293->1606 1rlrA2 c.7.1.2 * 1.1e-68 40.0 %
:RPS:PFM   207->289,1293->1594 PF02867 * Ribonuc_red_lgC 4e-50 45.1 %
:RPS:PFM   729->896 PF02867 * Ribonuc_red_lgC 1e-22 38.2 %
:RPS:PFM   898->992 PF07591 * DUF1557 5e-06 43.8 %
:HMM:PFM   81->131 PF02867 * Ribonuc_red_lgC 3.6e-05 38.3 47/533  
:HMM:PFM   207->274 PF02867 * Ribonuc_red_lgC 1.9e-08 41.8 67/533  
:HMM:PFM   734->886 PF02867 * Ribonuc_red_lgC 7.6e-27 36.0 139/533  
:HMM:PFM   1293->1419 PF02867 * Ribonuc_red_lgC 1.5e-36 47.2 127/533  
:HMM:PFM   1430->1594 PF02867 * Ribonuc_red_lgC 4.3e-31 34.7 147/533  
:HMM:PFM   6->78 PF00317 * Ribonuc_red_lgN 7.7e-13 35.6 73/83  
:HMM:PFM   1693->1742 PF10015 * DUF2258 0.00049 26.0 50/75  
:BLT:SWISS 57->131 RIR1_PLAFG 5e-04 31.9 %
:BLT:SWISS 289->737 DNAB_ANASP 7e-16 26.9 %
:BLT:SWISS 738->1410 NRDEB_BPSPC 3e-36 27.3 %
:REPEAT 2|131->736|738->1292
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAS82272.1 GT:GENE AAS82272.1 GT:PRODUCT ribonucleoside-diphosphate reductase alpha chain GT:DATABASE GIB00176CH01 GT:ORG tthe0 GB:ACCESSION GIB00176CH01 GB:LOCATION complement(1834737..1840139) GB:FROM 1834737 GB:TO 1840139 GB:DIRECTION - GB:PRODUCT ribonucleoside-diphosphate reductase alpha chain GB:PROTEIN_ID AAS82272.1 GB:DB_XREF GI:46197860 LENGTH 1800 SQ:AASEQ MRDGYFFDEHAQAIARRQYLQPGDGDILGMFRRVAREIAKAEREEERSKWEEEFFRLMAEKRFSPGGRILAGAGTVHGNLLNCFVQGATENPPESFAGIMEVAKKLALVTKVGGGNGVNLDPYRSKGKRARRAVEGVAYLSAEHPDVEDFIRGLMRPPINPDGAKEEISLKNFARVVYGALSPELKALAERYGVRTVKEPPEGRILVPDDMGGIIDAAREAADLARKGQKPHVDFSLLRPEGAPIRGSGGTSSGPVSFLFEIFDNFLEWVAWGAEEAGPVATLRYVYAPVLRVVRQGGCLHPDTLVHTDRGTLRLRELVDPFRRGWQPHTLSVATDEGWRPSPEGYNNGVAPTLRVVLENGLEVQGTLNHKLKVLREDGTREWVELQDLRPGDWVIWVLDEHTGTPVQLAPLDEPLHPNTTPIRTPEVLTEDLAFLLGFFFGEGFVSGDRIGFSVHEEEPMREEAKRLFRELFGLELREERKPGDRSVTLVVRSRPLVTWLRKNGLLKGKARELEVPRAIRQSPRPVLAAFLRGLFEADGTITAGYPMLTTASKRLAQDVMVLLGGLGIPSKLLRYNPLPGRFSKAEHYGVRVVTAKGLERYLERIGVPKGSRLEALHGIKPDVRRESSWPLPHAEGLLKPLLTVTEKGRKGYASPYTPLRKDLLRYLRGERQLTATGYAMVLEKAQDLGLEAEPFPFNEYYVRVASVEPGGEILTLDLSVEGNHTYLANGLVSHNTRRGAGMATLSIEHPDLLDFLTAKDLDREKAEGDISTFNISVLATDRFLEAVEKDELWPVTPIEVPGKYYPYPVEGPYTGKLPSLPEREDGAKAIPLYGGKVPARWLWHEIAWHAWATGEPGLIFVDRVNALSALKGLGERYQIRSTNPCFVGSTRIPTERGLVPIEELAREGGSFYLVTDNRAPFGGRGAPLPGHGTAVRKAVRAFFTGVKPVVRLRTREGLEVTLTPDHLLLTPEGYREAGKLRPGEKILVQSGEGLFPKEESLPAQALAVVHERVATAGGRGGRGRADVRAQYRNLPTRWSRELGVALGWLLGDGYLREDGVGFYFSRKDFADLAWLPDLLRDWFGPGTLQETRSNTFHLHFNRIPAEFFQALGVKAARATEKRVPESLFRAPREAVVGFLQGLFSADGSVQINENKQDATVRLASSSLALLQDVQLLLLNLGILGKIHKRREAARKALPDGKGGLREYPVAPQYELILGGENRDRFAEVVGFLQEEKQSKLLAFLRHRPRGSYRKPFLATVASVEPAGEAPVYDLTEPVTHSLIANGLVAHNCGEIPLTVGEPCDLGAMNLAAYVKDGEFQMEEFRRDVRTAIRFLDNVLDVNKFALPDNEMAAKSLRRLGLGLMGLADALIKMGLPYDSEEARRKVYEIVSVMREEAIRASEALAEERGPFPLYEEHREYFQSLGIRPRRNVALLTVAPTGTTSMLMGVSSGIEPVFSPFVWRRIGGEYKPLLHPLFVELMEAYPPAPGYAKDGKWDWEKIIEEIQKDGHGSVQNLPFVPEAIRKVFLCAHDVHPLDHVRMQGAVQRAFDAEGYAANSISKTINLPNHAAVEDVEAAYTEAYRTGCKGITVYRDGSREFQVLTVKKEAKEEKAGKTPEEAKPQEARAHEPGRPVYERPGRLMGFTDMVKLFAPDGSKRSFLVTVNTLEGRPIEVILTSGKAGDEANADSEALGRVVSIALQYGVPPEAIVRTLRGINGGLYGTYQGRLVSSKADLIAVALETVPQMAPGAPEDLSSAPVLSGGGIALAGAAPCPSCGEKALVREEGCWKCQACGYAKCG GT:EXON 1|1-1800:0| BL:SWS:NREP 3 BL:SWS:REP 57->131|RIR1_PLAFG|5e-04|31.9|72/804| BL:SWS:REP 289->737|DNAB_ANASP|7e-16|26.9|413/879| BL:SWS:REP 738->1410|NRDEB_BPSPC|3e-36|27.3|611/1084| NREPEAT 1 REPEAT 2|131->736|738->1292| SEG 32->56|rrvareiakaereeerskweeeffr| SEG 433->445|lafllgfffgegf| SEG 467->481|rlfrelfglelreer| SEG 1013->1030|rvataggrggrgradvra| SEG 1163->1185|lassslallqdvqllllnlgilg| SEG 1357->1367|lrrlglglmgl| SEG 1606->1622|kkeakeekagktpeeak| SEG 1763->1772|gggialagaa| BL:PDB:NREP 4 BL:PDB:REP 57->172|2zlgA|6e-06|27.7|107/654| BL:PDB:REP 207->274,1293->1597|1xjfA|7e-48|42.2|354/619| BL:PDB:REP 738->886|1xjnB|1e-07|29.6|107/610| BL:PDB:REP 915->993|2in9A|4e-07|39.7|78/139| RP:PDB:NREP 5 RP:PDB:REP 57->173,1291->1593|2cvtA|1e-56|18.8|385/637| RP:PDB:REP 173->270|2cvwA|3e-12|23.3|97/649| RP:PDB:REP 299->736|1dq3A|2e-26|13.5|415/454| RP:PDB:REP 736->942|2cvtA|5e-31|21.4|183/637| RP:PDB:REP 1033->1292|2cw8A|2e-19|17.0|253/528| RP:PFM:NREP 3 RP:PFM:REP 207->289,1293->1594|PF02867|4e-50|45.1|346/506|Ribonuc_red_lgC| RP:PFM:REP 729->896|PF02867|1e-22|38.2|150/506|Ribonuc_red_lgC| RP:PFM:REP 898->992|PF07591|5e-06|43.8|80/126|DUF1557| HM:PFM:NREP 7 HM:PFM:REP 81->131|PF02867|3.6e-05|38.3|47/533|Ribonuc_red_lgC| HM:PFM:REP 207->274|PF02867|1.9e-08|41.8|67/533|Ribonuc_red_lgC| HM:PFM:REP 734->886|PF02867|7.6e-27|36.0|139/533|Ribonuc_red_lgC| HM:PFM:REP 1293->1419|PF02867|1.5e-36|47.2|127/533|Ribonuc_red_lgC| HM:PFM:REP 1430->1594|PF02867|4.3e-31|34.7|147/533|Ribonuc_red_lgC| HM:PFM:REP 6->78|PF00317|7.7e-13|35.6|73/83|Ribonuc_red_lgN| HM:PFM:REP 1693->1742|PF10015|0.00049|26.0|50/75|DUF2258| GO:PFM:NREP 6 GO:PFM GO:0004748|"GO:ribonucleoside-diphosphate reductase activity"|PF02867|IPR000788| GO:PFM GO:0005971|"GO:ribonucleoside-diphosphate reductase complex"|PF02867|IPR000788| GO:PFM GO:0006260|"GO:DNA replication"|PF02867|IPR000788| GO:PFM GO:0004748|"GO:ribonucleoside-diphosphate reductase activity"|PF02867|IPR000788| GO:PFM GO:0005971|"GO:ribonucleoside-diphosphate reductase complex"|PF02867|IPR000788| GO:PFM GO:0006260|"GO:DNA replication"|PF02867|IPR000788| RP:SCP:NREP 7 RP:SCP:REP 57->265,1232->1605|1l1lA|3e-73|18.4|539/717|c.7.1.4| RP:SCP:REP 298->428,701->736|1am2A|2e-14|20.6|162/181|b.86.1.2| RP:SCP:REP 516->607|1dfaA3|5e-15|17.4|92/117|d.95.2.2| RP:SCP:REP 734->886|1r1rA2|3e-27|19.5|145/516|c.7.1.2| RP:SCP:REP 886->1009|1am2A|2e-14|22.6|113/181|b.86.1.2| RP:SCP:REP 1121->1246|1dfaA3|8e-11|13.4|114/117|d.95.2.2| RP:SCP:REP 1774->1796|1pftA|1e-04|43.5|23/50|g.41.3.1| HM:SCP:REP 5->152|1l1lA_|1.9e-15|35.0|140/721|c.7.1.4|1/4|PFL-like glycyl radical enzymes| HM:SCP:REP 207->273|1peqA2|1.9e-06|42.4|66/525|c.7.1.2|2/4|PFL-like glycyl radical enzymes| HM:SCP:REP 298->736|1am2A_|2.6e-38|36.2|188/199|b.86.1.2|1/2|Hedgehog/intein (Hint) domain| HM:SCP:REP 734->886|1peqA2|2.5e-24|35.5|141/525|c.7.1.2|3/4|PFL-like glycyl radical enzymes| HM:SCP:REP 885->1292|1am2A_|3.1e-39|39.7|189/199|b.86.1.2|2/2|Hedgehog/intein (Hint) domain| HM:SCP:REP 1293->1606|1rlrA2|1.1e-68|40.0|260/525|c.7.1.2|4/4|PFL-like glycyl radical enzymes| OP:NHOMO 577 OP:NHOMOORG 460 OP:PATTERN 11---11111111111-111111112221222--1--------1111-1-111-11111111111-11 21112------------11-1-----11111-1111----2211---2-111------1122121222223-----------1-1321111111111--1---21112211------11-----1--1----1-1-111--323121------1111-------1-1-1--------------1112211-2------------------2---1----1-11--111111-1-----------------1---------------------------------------------------------------------------1-11-111111111--1111111-12---111--1-1111111-1--2311--2-------11121112-11--------------------1-11---------------1-11211111-1--------1----111-----------------------------------1---121121111111222122221313222221132221122224212111111122-------111111211-111111-111111112121122221221---------------------------11--21--------------------------11312--------------------------------------------------------------------------------------------11111111112121----------------1111111---21222211111111121111---------1--1--------------------------1----------------------------------1--------1-111111111-- --11--1--------111------------111----111--1-111111111111-------12111-1--1111--11112122-1-11-1111---11113221-------1-----------11---------------------------------43111-111-1-111-----------12----111112 ----------------1-------------------------------------------------------------------------------------------------1-----------1--------------------------------------------11-- STR:NPRED 1597 STR:RPRED 88.7 SQ:SECSTR TccccccHHHHHHHHHHTccccTTcccccccHHHHHHHHHHHHHTTcHHHHHHHHHHHHTTcEEEcHHHHHHTTcccccccccEEEEccccccccHHHHHHHHHHHHHTTTccccEEEEcTTcccTTccTcccccEEEEEcTTcTTHHHHHHGGTTccEEccccTTccccTTEETTEEEEEEcHHHHHHTTcccccEEEccccEEEccccHHHHHHHHHHHHHHHTTTcEEEEEcTTcccTTcccTTccccccccHHHHHHHHHHHHHHTcccccEEEcEEEEEHEEEEETTEEEEcccEETTcEEEEEccccEEEEEHHHHHHHHGGGcEEEETTTTEEEEEcEEEcTTccEEEEEETTccEEEEcTTcEEEEEcTTccEEEEETTTccTTcEEcccccccccccccHHHHHHHHHHHHEEEEEEEcccTTcccEEEEEEEEEccHHHHHHHHHHHHHHHccccccEEHTTcccEEEccccTccccEEEEEccHHHHHHHHHHHTTcHTTGGGcccHHHHTTcHHHHHHHHHHHHHHHcEEETTTEEEEEccHHHHHHHHHHHHTTTcccEEEEEEcGGGEccccEEEEEEEccHHHHHHHHHHTGcccHHHHHHHHHHHHcccccccEEcccHHHHHHHHHTTTcEEETTEEEEEETTEEEEcTTHHHHccHHHHHHHHHHHHHHccHHHHHHHHHHHHcEEEEEEEEEcccEEEEEEETTTcEEEEEcEEEEccEcccEEEEEETTcTTHHHHTTcccccccccTTcccccEEEEEccTHHHHHHHTccEEEEEHHHHHHHHcHHHHHcccGGGccccTTHHHHHHcccccEEEEEHHHHHHHHHHHHHHHcccEEEcHHHHHHHcccccTccccccccccccccTTcEEEcTTcEEEGGGccTcTTcccccTTccEEEEHHHHcHTcccccccccEEEEEEEEEEcccccccccccTTccccccEEEEETTcEEEEEEEcEEEccccccccccccccEEEEEEEEEcTTccEEEEEEEEccccccccccEEEEEEEGGGGGGccHHHHHHccEEEccccccccTTcHHHHHHHHHHHHHHccTTcccccccTTcHHHHHHHHHHHHHTcccccccccccccGGGGTccHHHHHHHHHHHHHHHccEEcTTccETTEEEEEEccHHHHHHHHHHHHHTTcEEEEEEEEcccccTTcEcccGGGTccccEEEEEEEcTHHHHHHHTTcccTTTccccccccccccGHHHHccEEEcEEEEEHHHcccEEEEHHHHHHTcTTTTccccccccTTccccccTTccEEEEETTTTEcccEEcHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHcccEEEEEcHHHHHHHTTccTTcTTHHHHHHHHHHHHHHHHHHHHHHHHHHHcccTTcTTcTcGGTcTGGGTccHHHHTTccccccccHHHHHHHHHHHccccccccccccHcccccccHHHHHHHHTcHHHccHHHccccTTHHcccHHHHccccccccTTccHHHHHHcccTTTccHHHHHHHHHHHGGHcccccGccccccccccccccccTTHHHHHHHHHHHTTcccccccEEcc########################################################################################################################################################################################################### DISOP:02AL 1607-1639, 1748-1763| PSIPRED cccHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHccEEcccccEEEccccccccEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHHccEEEEEccccccccccccccEEEEEEEccccccHHHHHHHHccccccccccccHHHHHHHHHHHHHHHcHHHHHHHHHccEEEEEccccEEEEccHHHHHHHHHHHHHHHHHHHcccEEEEcHHHHHcccccccccccccccccHHHHHHHHHHHHHHHccccccEEEEEEcccccEEEEEccccccccccEEEEcccEEEEHHHHHHHHcccccEEEEEEccccccccccEEEEcccEEEEEEEcccEEEEEccccEEEEEEcccEEEEEEHHHcccccEEEEEccccccccccccccccccccccccccccccccHHHHHHHHHHHcccEEEccEEEEEEcccHHHHHHHHHHHHHHcccccEEEEEcccEEEEEEEEcHHHHHHHHHccccccccccccccHHHHHccHHHHHHHHHHHHHcccEEEccEEEEEEccHHHHHHHHHHHHHcccEEEEEEEcccccccccccEEEEEEEEcHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHccccccccccccHHHcccccccccHHHccHHHHHHHHHHHHcccccEEcccccHHcccccEEcccccEEEEEEEEHHHHHHHHHHHHcccccccccEEEEEcccHHHHHHHHcccccccccHHHHHHccccccccHHHHHHHHccccEEEccccccccccccccccccccHHHHHHHHHHHHcccccEEEEEcHHHHHHHHHHHHHHHccccEEEEEHHHHHccHHHcccEEEEEEEcccccccccccccccccHHHHHHHccccEEEEEccccccccccEEEEEcccEEEEEEEEEEcccccHHHHHcccccEEEEEccEEEEEEcccccHHHcccccEEEEEEccccccHHHHHHHHHHHHHHHHHccccccccccccHHcccccccccccHHHHHHHHHHHHccccEEcccEEEEEccHHHHHHHHHHHHHHHHccccEEEEEEccEEEEEccHHHHHHHHHHcccccccccccccHHHHcccHHHHHHHHHHHHHcccEEEEccccccEEEEEEEccHHHHHHHHHHHHHccccEEEEEccccccEEEEEccccEEEccccccEEEcccHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHcccccEEEEEcccccccccccccEEcccccEEEcccccccHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHcccEEEEHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHccHHHHHHHHccccccEEEEEEccHHHHHHHHccccccccccccEEEEEEcccEEEEcHHHHHHHHHHccHHHHHHHHccccHHHHHHHHHHHccccccccccccHHHHHHHccHHcccHHHHHHHHHHHHHHHHcccccccccccEEEccccccHHHHHHHHHHHHHccccEEEEEEccccccccEEEccHHHHHcccccccHHccccccEEEEccccccccccccEEEEEEEEEEEcccEEEEEEEEEEccccEEEEEEccccccHHHHHHHHHHHHHHHHHHHccccHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccccccccccccccEEEEEcccccccccccccccc //